腫瘍溶解性ウイルスとは?

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腫瘍溶解性ウイルス

出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2018/07/09 03:49 UTC 版)

腫瘍溶解性ウイルス(しゅようようかいせいウイルス、: oncolytic virus)とは、癌細胞に感染してこれを細胞死させるウイルスの総称である[1][2]。感染した癌細胞は融解し、感染性を持つ新たなウイルス粒子を放出して他の癌細胞に感染する[3]。腫瘍溶解性ウイルスは腫瘍細胞を直接死に至らしめるのみならず、宿主の抗腫瘍免疫活性を上昇させる[4][5]


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