チミジンキナーゼとは？ わかりやすく解説

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チミジンキナーゼ【thymidinekinase】

読み方：ちみじんきなーぜ

デオキシチミジン（DNAの構成成分）を燐酸化する酵素。癌(がん)細胞ではこの酵素の活性が高い。


生物学用語辞典
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チミジンキナーゼ

英訳・(英)同義/類義語：thymidine kinase

チミジンとATPを基質とし、TMPを合成する酵素。
「生物学用語辞典」の他の用語
酵素タンパク質モチーフなど：  タンパク選別シグナル  ターミナルデオキシリボヌクレオチジルトランスフェラーゼ  ターミナーゼ  チミジンキナーゼ  チロキシン結合グロブリン  チロキシン結合プレアルブミン  チロシンキナーゼ

ウィキペディア
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ウィキペディアウィキペディア

チミジンキナーゼ

出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/11/13 10:02 UTC 版)

チミジンキナーゼ（英: thymidine kinase、略称: TK、EC 2.7.1.21）は酵素（ホスホトランスフェラーゼ、キナーゼ）であり、より具体的には2'-デオキシチミジンキナーゼ（2'-deoxythymidine kinase）、ATP-チミジン 5'-ホスホトランスフェラーゼ（ATP-thymidine 5'-phosphotransferase）である[2][3]。大部分の細胞に存在し、哺乳類細胞にはTK1（英語版）、TK2（英語版）という2種類が存在する。特定のウイルスもチミジンキナーゼを発現するための遺伝情報を保有している。チミジンキナーゼは次の反応を触媒する。


出典
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チミジンキナーゼのお隣キーワード

チミケップ湖 (小惑星)

チミジル酸

チミジル酸-5'-ホスファターゼ

チミジル酸シンターゼ(FAD)

チミジル酸合成酵素

チミジン

チミジンキナーゼ

チミジントリホスファターゼ

チミジン一リン酸

チミジン三リン酸

チミジン二リン酸

チミジン二量体

チミジン標識法

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 英語⇒日本語
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