せいめい‐じょうほうかがく〔‐ジヤウホウクワガク〕【生命情報科学】
読み方：せいめいじょうほうかがく
バイオインフォマティクス、生命情報科学
バイオインフォマティクス
(生命情報科学 から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2024/04/09 21:02 UTC 版)
バイオインフォマティクス（英語：bioinformatics）とは、生命科学と情報科学の融合分野のひとつであり、DNAやRNA、タンパク質をはじめとする、生命が持つ様々な「情報」を対象に、情報科学や統計学などのアルゴリズムを用いた方法論やソフトウェアを開発し、またそれらを用いた分析から生命現象を解き明かしていく(in silico 解析)ことを目的とした学問分野である。そのためバイオインフォマティクスは広義には、生物学、コンピュータサイエンス、情報工学、数学、統計学といった様々な学問分野が組み合わさった学際分野自体を指す。日本語では生命情報科学や生物情報学、情報生命科学などと表記される。
- ^ Lesk (2013年7月26日). “Bioinformatics”. Encyclopaedia Britannica. 2017年4月17日閲覧。
- ^ a b Sim, A. Y. L.; Minary, P.; Levitt, M. (2012). “Modeling nucleic acids”. Current Opinion in Structural Biology 22 (3): 273-78. doi:10.1016/j.sbi.2012.03.012. PMC 4028509. PMID 22538125.
- ^ Dawson, W. K.; Maciejczyk, M.; Jankowska, E. J.; Bujnicki, J. M. (2016). “Coarse-grained modeling of RNA 3D structure”. Methods 103: 138-56. doi:10.1016/j.ymeth.2016.04.026. PMID 27125734.
- ^ Kmiecik, S.; Gront, D.; Kolinski, M.; Wieteska, L.; Dawid, A. E.; Kolinski, A. (2016). “Coarse-Grained Protein Models and Their Applications”. Chemical Reviews 116 (14): 7898-936. doi:10.1021/acs.chemrev.6b00163. PMID 27333362.
- ^ Wong, K. C. (2016). Computational Biology and Bioinformatics: Gene Regulation. CRC Press/Taylor & Francis Group. ISBN 9781498724975
- ^ Joyce, A. P.; Zhang, C.; Bradley, P.; Havranek, J. J. (2015). “Structure-based modeling of protein: DNA specificity”. Briefings in Functional Genomics 14 (1): 39-49. doi:10.1093/bfgp/elu044. PMC 4366589. PMID 25414269.
- ^ Spiga, E.; Degiacomi, M. T.; Dal Peraro, M. (2014). “New Strategies for Integrative Dynamic Modeling of Macromolecular Assembly”. In Karabencheva-Christova, T.. Biomolecular Modelling and Simulations. Advances in Protein Chemistry and Structural Biology. 96. Academic Press. pp. 77-111. doi:10.1016/bs.apcsb.2014.06.008. ISBN 9780128000137. PMID 25443955
- ^ Ciemny, Maciej; Kurcinski, Mateusz; Kamel, Karol; Kolinski, Andrzej; Alam, Nawsad; Schueler-Furman, Ora; Kmiecik, Sebastian (2018-05-04). “Protein-peptide docking: opportunities and challenges” (英語). Drug Discovery Today 23 (8): 1530-37. doi:10.1016/j.drudis.2018.05.006. ISSN 1359-6446. PMID 29733895.
- ^ a b Hogeweg P (2011). “The Roots of Bioinformatics in Theoretical Biology”. PLOS Computational Biology 7 (3): e1002021. Bibcode: 2011PLSCB...7E2021H. doi:10.1371/journal.pcbi.1002021. PMC 3068925. PMID 21483479.
- ^ Bioinformatica: een werkconcept. 1. Kameleon. (1970). pp. 28-29.
- ^ Hogeweg P (1978). “Simulating the growth of cellular forms”. Simulation 31 (3): 90-96. doi:10.1177/003754977803100305.
- ^ Moody, Glyn (2004). Digital Code of Life: How Bioinformatics is Revolutionizing Science, Medicine, and Business. ISBN 978-0-471-32788-2
- ^ Dayhoff, M.O. (1966) Atlas of protein sequence and structure. National Biomedical Research Foundation, 215 pp.
- ^ “Evolution of the structure of ferredoxin based on living relics of primitive amino Acid sequences”. Science 152 (3720): 363-366. (1966). Bibcode: 1966Sci...152..363E. doi:10.1126/science.152.3720.363. PMID 17775169.
- ^ “Kabat Database and its applications: 30 years after the first variability plot”. Nucleic Acids Res 28 (1): 214-218. (January 2000). doi:10.1093/nar/28.1.214. PMC 102431. PMID 10592229.
- ^ Xiong, Jin (2006). Essential Bioinformatics. Cambridge, United Kingdom: Cambridge University Press. pp. 4. ISBN 978-0-511-16815-4
- ^ “GenBank”. Nucleic Acids Res. 36 (Database issue): D25-30. (January 2008). doi:10.1093/nar/gkm929. PMC 2238942. PMID 18073190.
- ^ a b c “Whole-genome random sequencing and assembly of Haemophilus influenzae Rd”. Science 269 (5223): 496-512. (July 1995). Bibcode: 1995Sci...269..496F. doi:10.1126/science.7542800. PMID 7542800.
- ^ Carvajal-Rodriguez A (2012). “Simulation of Genes and Genomes Forward in Time”. Current Genomics 11 (1): 58-61. doi:10.2174/138920210790218007. PMC 2851118. PMID 20808525.
- ^ Brown, TA (2002). “Mutation, Repair and Recombination”. Genomes (2nd ed.). Manchester (UK): Oxford
- ^ Carter, N. P.; Fiegler, H.; Piper, J. (2002). “Comparative analysis of comparative genomic hybridization microarray technologies: Report of a workshop sponsored by the Wellcome trust”. Cytometry Part A 49 (2): 43-48. doi:10.1002/cyto.10153. PMID 12357458.
- ^ Hiraoka, Satoshi; Yang, Ching-chia; Iwasaki, Wataru (2016). “Metagenomics and Bioinformatics in Microbial Ecology: Current Status and Beyond” (英語). Microbes and environments 31 (3): 204-212. doi:10.1264/jsme2.ME16024. ISSN 1342-6311. PMC 5017796. PMID 27383682.
- ^ Chaudhari Narendrakumar M., Kumar Gupta Vinod, Dutta Chitra (2016). “BPGA-an ultra-fast pan-genome analysis pipeline”. Scientific Reports 6: 24373. Bibcode: 2016NatSR...624373C. doi:10.1038/srep24373. PMC 4829868. PMID 27071527.
- ^ Aston KI (2014). “Genetic susceptibility to male infertility: News from genome-wide association studies”. Andrology 2 (3): 315-21. doi:10.1111/j.2047-2927.2014.00188.x. PMID 24574159.
- ^ “Genome-wide association studies and the clinic: A focus on breast cancer”. Biomarkers in Medicine 8 (2): 287-96. (2014). doi:10.2217/bmm.13.121. PMID 24521025.
- ^ “Genome-wide association studies in Alzheimer's disease: A review”. Current Neurology and Neuroscience Reports 13 (10): 381. (2013). doi:10.1007/s11910-013-0381-0. PMC 3809844. PMID 23954969.
- ^ Use of Linkage Analysis, Genome-Wide Association Studies, and Next-Generation Sequencing in the Identification of Disease-Causing Mutations. Methods in Molecular Biology. 1015. (2013). 127-46. doi:10.1007/978-1-62703-435-7_8. ISBN 978-1-62703-434-0. PMID 23824853
- ^ Hindorff, L.A. (2009). “Potential etiologic and functional implications of genome-wide association loci for human diseases and traits”. Proc. Natl. Acad. Sci. USA 106 (23): 9362-9367. Bibcode: 2009PNAS..106.9362H. doi:10.1073/pnas.0903103106. PMC 2687147. PMID 19474294.
- ^ Hall, L.O. (2010). Finding the right genes for disease and prognosis prediction. 1-2. doi:10.1109/ICSSE.2010.5551766. ISBN 978-1-4244-6472-2
- ^ Vazquez, Miguel; Torre, Victor de la; Valencia, Alfonso (2012-12-27). “Chapter 14: Cancer Genome Analysis” (英語). PLOS Computational Biology 8 (12): e1002824. Bibcode: 2012PLSCB...8E2824V. doi:10.1371/journal.pcbi.1002824. ISSN 1553-7358. PMC 3531315. PMID 23300415.
- ^ Hye-Jung, E.C.; Jaswinder, K.; Martin, K.; Samuel, A.A; Marco, A.M (2014). “Second-Generation Sequencing for Cancer Genome Analysis”. In Dellaire, Graham; Berman, Jason N.; Arceci, Robert J.. Cancer Genomics. Boston (US): Academic Press. pp. 13-30. doi:10.1016/B978-0-12-396967-5.00002-5. ISBN 9780123969675
- ^ Grau, J.; Ben-Gal, I.; Posch, S.; Grosse, I. (1 July 2006). “VOMBAT: prediction of transcription factor binding sites using variable order Bayesian trees”. Nucleic Acids Research 34 (Web Server): W529-W533. doi:10.1093/nar/gkl212. PMC 1538886. PMID 16845064.
- ^ “The Human Protein Atlas”. www.proteinatlas.org. 2017年10月2日閲覧。
- ^ “The human cell”. www.proteinatlas.org. 2017年10月2日閲覧。
- ^ Thul, Peter J.; Åkesson, Lovisa; Wiking, Mikaela; Mahdessian, Diana; Geladaki, Aikaterini; Blal, Hammou Ait; Alm, Tove; Asplund, Anna et al. (2017-05-26). “A subcellular map of the human proteome”. Science 356 (6340): eaal3321. doi:10.1126/science.aal3321. PMID 28495876.
- ^ Ay, Ferhat; Noble, William S. (2 September 2015). “Analysis methods for studying the 3D architecture of the genome”. Genome Biology 16 (1): 183. doi:10.1186/s13059-015-0745-7. PMC 4556012. PMID 26328929.
- ^ Hoy, JA; Robinson, H; Trent JT, 3rd; Kakar, S; Smagghe, BJ; Hargrove, MS (3 August 2007). “Plant hemoglobins: a molecular fossil record for the evolution of oxygen transport”. Journal of Molecular Biology 371 (1): 168-79. doi:10.1016/j.jmb.2007.05.029. PMID 17560601.
- ^ a b “Open Bioinformatics Foundation: About us”. Official website. Open Bioinformatics Foundation. 2011年5月10日閲覧。
- ^ “Open Bioinformatics Foundation: BOSC”. Official website. Open Bioinformatics Foundation. 2011年5月10日閲覧。
- ^ Brohée, Sylvain; Barriot, Roland; Moreau, Yves (2010). “Biological knowledge bases using Wikis: combining the flexibility of Wikis with the structure of databases”. Bioinformatics 26 (17): 2210-2211. doi:10.1093/bioinformatics/btq348. PMID 20591906 2015年5月5日閲覧。.
- ^ Nisbet, Robert (2009). “Bioinformatics”. Handbook of Statistical Analysis and Data Mining Applications. John Elder IV, Gary Miner. Academic Press. p. 328. ISBN 978-0080912035 2014年5月9日閲覧。
- ^ Commissioner. “Advancing Regulatory Science - Sept. 24-25, 2014 Public Workshop: Next Generation Sequencing Standards” (英語). www.fda.gov. 2017年11月30日閲覧。
- ^ Simonyan, Vahan; Goecks, Jeremy; Mazumder, Raja (2017). “Biocompute Objects ? A Step towards Evaluation and Validation of Biomedical Scientific Computations”. PDA Journal of Pharmaceutical Science and Technology 71 (2): 136-46. doi:10.5731/pdajpst.2016.006734. ISSN 1079-7440. PMC 5510742. PMID 27974626.
- ^ Alterovitz, Gil; Dean, Dennis; Goble, Carole; Crusoe, Michael R.; Soiland-Reyes, Stian; Bell, Amanda; Hayes, Anais; Suresh, Anita et al. (2017-09-21) (英語). Enabling Precision Medicine via standard communication of HTS provenance, analysis, and results. doi:10.1101/191783.
- ^ BioCompute Object (BCO) project is a collaborative and community-driven framework to standardize HTS computational data. 1. BCO Specification Document: user manual for understanding and creating B., biocompute-objects, (2017-09-03) 2017年11月30日閲覧。
- ^ Barker, D; Ferrier, D.E.K.; Holland, P.W; Mitchell, J.B.O; Plaisier, H; Ritchie, M.G; Smart, S.D. (2013). “4273π : bioinformatics education on low cost ARM hardware”. BMC Bioinformatics 14: 243. doi:10.1186/1471-2105-14-243. PMC 3751261. PMID 23937194.
- ^ Barker, D; Alderson, R.G; McDonagh, J.L; Plaisier, H; Comrie, M.M; Duncan, L; Muirhead, G.T.P; Sweeny, S.D. (2015). “University-level practical activities in bioinformatics benefit voluntary groups of pupils in the last 2 years of school”. International Journal of STEM Education 2 (17). doi:10.1186/s40594-015-0030-z.
- ^ McDonagh, J.L; Barker, D; Alderson, R.G. (2016). “Bringing computational science to the public”. SpringerPlus 5 (259): 259. doi:10.1186/s40064-016-1856-7. PMC 4775721. PMID 27006868.
- ^ Robson, J.F.; Barker, D (2015). “Comparison of the protein-coding gene content of Chlamydia trachomatis and Protochlamydia amoebophila using a Raspberry Pi computer”. BMC Research Notes 8 (561): 561. doi:10.1186/s13104-015-1476-2. PMC 4604092. PMID 26462790.
- ^ Wregglesworth, K.M; Barker, D (2015). “A comparison of the protein-coding genomes of two green sulphur bacteria, Chlorobium tepidum TLS and Pelodictyon phaeoclathratiforme BU-1”. BMC Research Notes 8 (565): 565. doi:10.1186/s13104-015-1535-8. PMC 4606965. PMID 26467441.
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