長期増強
シナプス長期増強
英訳・(英)同義/類義語:synaps LTP, synaps long term potenciate
シナプスでの刺激伝達が活発に行われると伝達効率が高まり、刺激が消滅した後もその状態がしばらく保たれる現象。
現象や動作行為に関連する概念: | コンジェニック系統 シグナル伝達 シナプス型シグナル伝達 シナプス長期増強 スカベンジャー ストレス応答 セントラルドグマ |
長期増強
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2023/11/29 09:50 UTC 版)
神経科学の分野において、長期増強(ちょうきぞうきょう、英: Long-term potentiation、略称: LTP)は、神経細胞を同時刺激することにより2つの神経細胞間の信号伝達が持続的に向上する現象である[2]。神経細胞はシナプス結合を介して信号伝達しており、記憶はこのシナプスに貯えられていると信じられているので[3]、長期増強は学習と記憶の根底にある主要な細胞学的機構の1つであると広く考えられている[2]。
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- 1 長期増強とは
- 2 長期増強の概要
- 3 長期増強の特性
- 4 臨床面での重要性
- 5 脚注
長期増強
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2021/04/04 08:22 UTC 版)
SGKは海馬の神経細胞での長期増強と神経可塑性を促進することが示されている。海馬でのSGKのmRNAの発現はAMPA受容体によって増加する。AMPA受容体を介したシナプス伝達は長期増強の後期段階と密接に関係している。
※この「長期増強」の解説は、「SGK1」の解説の一部です。
「長期増強」を含む「SGK1」の記事については、「SGK1」の概要を参照ください。
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