テクネチウム99m
テクネチウム99m
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2024/01/18 22:32 UTC 版)
テクネチウム99m（Technetium-99m、99mTc）は、テクネチウムの同位体たるテクネチウム99の準安定核異性体である。年間数千万件の医療診断に使用されており、世界で最も頻用されている医療用放射性同位元素である。
- ^ “99mTc tables”. Nucleide.org. Laboratoire National Henri Becquerel (2012年1月17日). 2012年5月23日閲覧。
- ^ Segrè, Emilio; Seaborg, Glenn T. (1 November 1938). “Nuclear Isomerism in Element 43”. Physical Review 54 (9): 772. Bibcode: 1938PhRv...54..772S. doi:10.1103/PhysRev.54.772.2.
- ^ Hoffmann, Ghiorso & Seaborg 2000, pp. 15–16
- ^ Schwochau 2000, p. 4
- ^ Segrè, Emilio; Wu, Chien-Shiung (1940). “Some Fission Products of Uranium”. Physical Review 57 (6): 552. Bibcode: 1940PhRv...57..552S. doi:10.1103/PhysRev.57.552.3.
- ^ “Brookhaven Graphite Research Reactor”. bnl.gov. 2012年5月3日閲覧。
- ^ Richards, Powell (1989). Technetium-99m: The Early Days. BNL-43197 CONF-8909193-1. New York: Brookhaven National Laboratory 2012年3月3日閲覧。
- ^ Richards, Powell (1960). “A survey of the production at Brookhaven National Laboratory of radioisotopes for medical research”. VII Rassegna Internazionale Elettronica e Nucleare Roma: 223–244.
- ^ Richards, P.; Tucker, W. D.; Srivastava, S. C. (October 1982). “Technetium-99m: an historical perspective”. The International Journal of Applied Radiation and Isotopes 33 (10): 793–9. doi:10.1016/0020-708X(82)90120-X. PMID 6759417.
- ^ Stang, Louis G.; Richards, Powell (1964). “Tailoring the isotope to the need”. Nucleonics 22 (1). ISSN 0096-6207.
- ^ Herbert, R.; Kulke, W.; Shepherd, R. T. (November 1965). “The use of technetium 99m as a clinical tracer element.”. Postgraduate Medical Journal 41 (481): 656–62. doi:10.1136/pgmj.41.481.656. PMC 2483197. PMID 5840856.
- ^ Sorensen, Leif; Archambault, Maureen (1963). “Visualization of the liver by scanning with Mo99 (molybdate) as tracer”. The Journal of Laboratory and Clinical Medicine 62: 330–340. PMID 14057883.
- ^ a b Wald, Matthew L. (2009年7月23日). “Radioactive Drug for Tests Is in Short Supply”. New York Times.
- ^ Smith, Michael (2010年2月16日). “Looming Isotope Shortage Has Clinicians Worried”. MedPage Today. 2010年2月25日閲覧。
- ^ Ruth, Thomas (29 January 2009). “Accelerating production of medical isotopes”. Nature 457 (7229): 536–537. Bibcode: 2009Natur.457..536R. doi:10.1038/457536a. PMID 19177112.
- ^ de Widt, Eric Jan (2010). “The High Flux Reactor in Petten resumes the vital roles of production of medical radioisotopes and nuclear research”. Tijdschrift voor Nucleaire Geneeskunde 32 (4): 586–591. ISSN 1381-4842 2012年4月27日閲覧。.
- ^ Thomas, G. S.; Maddahi, J. (December 2010). “The Technetium Shortage”. Journal of Nuclear Cardiology 17 (6): 993–8. doi:10.1007/s12350-010-9281-8. PMID 20717761.
- ^ http://www.columbiatribune.com/news/20180810/business-seeks-tax-break-to-build-108m-facility
- ^ National Research Council 2009, p. 34 [1]
- ^ Raloff, Janet (2009). “Desperately Seeking Moly”. Science News 176 (7): 16–20. doi:10.1002/scin.5591760717.
- ^ “The Licensing for Decommissioning of Research Reactors in Indonesia of Research Reactors in Indonesia”. Iaea.org. 2012年4月26日閲覧。
- ^ “Centro Atómico Ezeiza”. CNEA.gob.ar. 2012年4月26日閲覧。
- ^ “REAKTOR LVR-15” (チェコ語). 2012年5月11日閲覧。
- ^ US 3382152, Ephraim Lieberman, "Production of high purity radioactive isotopes", issued May 7, 1968, assigned to Union Carbide Corporation
- ^ Our Work: Nuclear Fuel Cycle and Materials Section
- ^ Beaver, J. E.; Hupf, H.B. (November 1971). “Production of 99mTc on a Medical Cyclotron: a Feasibility Study”. Journal of Nuclear Medicine 12 (11): 739–41. PMID 5113635.
- ^ Schaffer1, P. (2015). “Direct Production of 99mTc via 100Mo(p,2n) on Small Medical Cyclotrons”. Physics Procedia 66: 383–395. Bibcode: 2015PhPro..66..383S. doi:10.1016/j.phpro.2015.05.048.
- ^ Alary, Bryan (2013年7月2日). “Cyclotron facility revolutionizes medical isotope manufacturing”. University of Alberta. 2013年7月6日閲覧。
- ^ Lougheed, Tim (20 June 2013). “Cyclotron production of medical isotopes scales up”. CMAJ (Ottawa: Canadian Medical Association) 185 (11): 947. doi:10.1503/cmaj.109-4525. ISSN 1488-2329. PMC 3735742. PMID 23798456. オリジナルの6 July 2013時点におけるアーカイブ。 2013年7月6日閲覧。.
- ^ Qaim, S. M.; Sudár, S.; Scholten, B.; Koning, A. J.; Coenen, H. H. (2014-02-01). “Evaluation of excitation functions of 100Mo(p,d+pn)99Mo and 100Mo (p,2n)99mTc reactions: Estimation of long-lived Tc-impurity and its implication on the specific activity of cyclotron-produced 99mTc” (英語). Applied Radiation and Isotopes 85: 101–113. doi:10.1016/j.apradiso.2013.10.004. ISSN 0969-8043. PMID 24389533.
- ^ Wolterbeek, Bert; Kloosterman, Jan Leen; Lathouwers, Danny; Rohde, Martin; Winkelman, August; Frima, Lodewijk; Wols, Frank (2014-11-01). “What is wise in the production of 99Mo? A comparison of eight possible production routes” (英語). Journal of Radioanalytical and Nuclear Chemistry 302 (2): 773–779. doi:10.1007/s10967-014-3188-9. ISSN 1588-2780.
- ^ Scholten, Bernhard; Lambrecht, Richard M.; Cogneau, Michel; Vera Ruiz, Hernan; Qaim, Syed M. (25 May 1999). “Excitation functions for the cyclotron production of 99mTc and 99Mo”. Applied Radiation and Isotopes 51 (1): 69–80. doi:10.1016/S0969-8043(98)00153-5.
- ^ Takács, S.; Szűcs, Z.; Tárkányi, F.; Hermanne, A.; Sonck, M. (1 January 2003). “Evaluation of proton induced reactions on 100Mo: New cross sections for production of 99mTc and 99Mo”. Journal of Radioanalytical and Nuclear Chemistry 257 (1): 195–201. doi:10.1023/A:1024790520036.
- ^ Celler, A.; Hou, X.; Bénard, F.; Ruth, T. (7 September 2011). “Theoretical modeling of yields for proton-induced reactions on natural and enriched molybdenum targets”. Physics in Medicine and Biology 56 (17): 5469–5484. Bibcode: 2011PMB....56.5469C. doi:10.1088/0031-9155/56/17/002. PMID 21813960.
- ^ Martin, T. Michael; Harahsheh, Talal; Munoz, Benjamin; Hamoui, Zaher; Clanton, Ryan; Douglas, Jordan; Brown, Peter; Akabani, Gamal (2017-11-01). “Production of 99Mo/99mTc via photoneutron reaction using natural molybdenum and enriched 100Mo: part 1, theoretical analysis” (英語). Journal of Radioanalytical and Nuclear Chemistry 314 (2): 1051–1062. doi:10.1007/s10967-017-5455-z. ISSN 1588-2780.
- ^ Nagai, Yasuki; Hatsukawa, Yuichi (2009-03-10). “Production of 99Mo for Nuclear Medicine by 100Mo(n,2n)99Mo”. Journal of the Physical Society of Japan 78 (3): 033201. Bibcode: 2009JPSJ...78c3201N. doi:10.1143/JPSJ.78.033201. ISSN 0031-9015.
- ^ Capogni, M.; Pietropaolo, A.; Quintieri, L.; Fazio, A.; Pillon, M.; De Felice, P.; Pizzuto, A. (2018). “14 MeV neutrons for medical application: a scientific case for 99Mo/99Tcm production”. Journal of Physics: Conference Series 1021: 012038. doi:10.1088/1742-6596/1021/1/012038 2020年11月16日閲覧。.
- ^ Ohta, Masayuki; Kwon, Saerom; Sato, Satoshi; Ochiai, Kentaro; Suzuki, Hiromitsu (2018-05-01). “Investigation of 99Mo radioisotope production by d-Li neutron source” (英語). Nuclear Materials and Energy 15: 261–266. doi:10.1016/j.nme.2018.05.017. ISSN 2352-1791.
- ^ Takahashi, Naruto; Nakai, Kozi; Shinohara, Atsushi; Htazawa, Jun; Nakamura, Masanobu; Fukuda, Mitsuhiro; Hatanaka, Kichiji; Morikawa, Yasumasa et al. (2012-05-01). “Production of 99Mo-99mTc by using spallation neutron” (英語). Journal of Nuclear Medicine 53 (supplement 1): 1475. ISSN 0161-5505.
- ^ Gagnon, K.; Wilson, J. S.; Holt, C. M. B.; Abrams, D. N.; McEwan, A. J. B.; Mitlin, D.; McQuarrie, S. A. (2012-08-01). “Cyclotron production of 99mTc: Recycling of enriched 100Mo metal targets” (英語). Applied Radiation and Isotopes 70 (8): 1685–1690. doi:10.1016/j.apradiso.2012.04.016. ISSN 0969-8043. PMID 22750197.
- ^ Tkac, Peter; Vandegrift, George F. (2016-04-01). “Recycle of enriched Mo targets for economic production of 99Mo/99mTc medical isotope without use of enriched uranium” (英語). Journal of Radioanalytical and Nuclear Chemistry 308 (1): 205–212. doi:10.1007/s10967-015-4357-1. ISSN 1588-2780. OSTI 1399098.
- ^ Moore, P. W. (April 1984). “Technetium-99 in generator systems.”. Journal of Nuclear Medicine 25 (4): 499–502. PMID 6100549 2012年5月11日閲覧。.
- ^ Dilworth, Jonathan R.; Parrott, Suzanne J. (1998). “The biomedical chemistry of technetium and rhenium”. Chemical Society Reviews 27: 43–55. doi:10.1039/a827043z.
- ^ Shaw, Ken B. (Spring 1985). “Worker Exposures: How Much in the UK?”. IAEA Bulletin. オリジナルの2011年9月5日時点におけるアーカイブ。 2012年5月19日閲覧。
- ^ a b Eckelman, William C. (2009). “Unparalleled Contribution of Technetium-99m to Medicine Over 5 Decades”. JACC: Cardiovascular Imaging 2 (3): 364–368. doi:10.1016/j.jcmg.2008.12.013. PMID 19356582 2012年4月18日閲覧。. Historical perspective, full text
- ^ Eckelman, William C.; Richards, Powell (December 1970). “Instant 99mTc-DTPA.”. Journal of Nuclear Medicine 11 (12): 761. PMID 5490410 2012年7月21日閲覧。.
- ^ Molinski, Victor J. (1 October 1982). “A review of 99mTc generator technology”. The International Journal of Applied Radiation and Isotopes 33 (10): 811–819. doi:10.1016/0020-708X(82)90122-3.
- ^ International Atomic Energy Agency (2008). Technetium-99m Radiopharmaceuticals: Manufacture of Kits. Vienna. ISBN 9789201004086 2012年7月21日閲覧。
- ^ Schwochau 2000, p. 414
- ^ Alberto, Roger; Nadeem, Qaisar (2021). “Chapter 7. 99m Technetium-Based Imaging Agents and Developments in 99Tc Chemistry”. Metal Ions in Bio-Imaging Techniques. Springer. pp. 195-238. doi:10.1515/9783110685701-013
- ^ Squibb, B.-M.. “Cardialite kit for the preparation of Technetium 99m Sestamibi for injection, Prescribing information, April 2008”. Food and Drug Administration. 2009年9月3日閲覧。
- ^ “Neurolite (bicisate dihydrochloride)”. National Institutes of Health. 2009年11月11日閲覧。
- ^ Bedetti, G.; Pizzi, C.; Gavaruzzi, G.; Lugaresi, F.; Cicognani, A.; Picano, E. (2008). “Suboptimal awareness of radiologic dose among patients undergoing cardiac stress scintigraphy”. J Am Coll Radiol 5 (2): 126–31. doi:10.1016/j.jacr.2007.07.020. PMID 18242529.
- ^ Committee to Assess the Health Risks from Exposure to Low Levels of Ionizing Radiation, BEIR VII, National Research Council. Health Risks From Exposure to Low Levels of Ionizing Radiation. Washington, DC: National Academies Press; 2006
- ^ Fahey, Frederic H.; Treves, S. Ted; Adelstein, S. James (1 August 2011). “Minimizing and Communicating Radiation Risk in Pediatric Nuclear Medicine”. Journal of Nuclear Medicine Technology 52 (8): 1240–1251. doi:10.2967/jnumed.109.069609.
- ^ a b http://www.xrayrisk.com/calculator/calculator-normal-studies.php
- ^ a b Merck manuals > Radionuclide Imaging Last full review/revision May 2009 by Michael J. Shea, MD. Content last modified May 2009
- ^ Gershenwald, J. E.; Ross, M. I. (2011-05-05). “Sentinel-Lymph-Node Biopsy for Cutaneous Melanoma”. New England Journal of Medicine 364 (18): 1738–1745. doi:10.1056/NEJMct1002967. ISSN 0028-4793. PMID 21542744.
- ^ “テクネピロリン酸キット 添付文書”. www.info.pmda.go.jp. PMDA. 2021年5月3日閲覧。
- ^ Rimshaw 1968, pp. 689–693
- ^ Nuclear Imaging of Meckel's Diverticulum: A Pictorial Essay of Pitfalls Archived 2012-01-17 at the Wayback Machine. S. Huynh, M.D., R. Amin, M.D., B. Barron, M.D., R. Dhekne, M.D., P. Nikolaidis, M.D., L. Lamki, M.D.. University of Texas Houston Medical School and Memorial Hermann - Texas Medical Center (TMC), St. Luke's Episcopal Hospital and Texas Children Hospital, Houston, Texas. Last Modified September 5, 2007
- ^ Diamond, Robert; Rothstein, Robin; Alavi, Abass (1991). “The Role of Cimetidine-Enhanced Technetium 99m-Pertechnetate Imaging for Visualizing Meckel's Diverticulum”. The Journal of Nuclear Medicine 32 (7): 1422–1424.
[続きの解説]
「テクネチウム99m」の続きの解説一覧
- 1 テクネチウム99mとは
- 2 テクネチウム99mの概要
- 3 製造
- 4 医学的用途
- 5 関連項目
- 6 外部リンク
- テクネチウム-99mのページへのリンク
