レチナール
| 分子式： | C20H28O |
| その他の名称： | ビタミンA3、ビタミンAアルデヒド、Retinal、Vitamin A3、Vitamin A aldehyde、ビタミンA1アルデヒド、trans-ビタミンAアルデヒド、all-trans-レチナール、trans-Vitamin A aldehyde、all-trans-Retinal、Vitamin A1 aldehyde、レチネン、Retinene、レチンアルデヒド、trans-Retinal、Retinene 1、Axerophthal、Retinaldehyde、E-レチナール、アキセロフタール、trans-レチナール、レチネン1、E-Retinal、all-trans-レチンアルデヒド、all-trans-Retinaldehyde、all-transレチナール、all-trans Retinal、全トランスレチナール、All-trans retinal、(2E,4E,6E,8E)-9-(2,6,6-Trimethyl-1-cyclohexenyl)-3,7-dimethyl-2,4,6,8-nonatetraenal |
| 体系名： | (2E,4E,6E,8E)-3,7-ジメチル-9-(2,6,6-トリメチル-1-シクロヘキセニル)-2,4,6,8-ノナテトラエナール、(2E,4E,6E,8E)-3,7-ジメチル-9-(2,6,6-トリメチル-1-シクロヘキセン-1-イル)-2,4,6,8-ノナテトラエナール、レチナール、(2E,4E,6E,8E)-9-(2,6,6-トリメチル-1-シクロヘキセニル)-3,7-ジメチル-2,4,6,8-ノナテトラエナール |
レチナール
レチナール
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/02/15 05:38 UTC 版)
レチナール（Retinal、レチンアルデヒドとも）は、ポリエンの発色団であり、オプシンと呼ばれるタンパク質に結合しており、動物の視覚の化学的基礎となる。
- ^ a b Merck Index, 13th Edition, 8249
- ^ WALD, GEORGE (14 July 1934). “Carotenoids and the Vitamin A Cycle in Vision”. Nature 134 (3376): 65. Bibcode: 1934Natur.134...65W. doi:10.1038/134065a0.
- ^ Wald, G (11 October 1968). “Molecular basis of visual excitation.”. Science 162 (3850): 230–9. Bibcode: 1968Sci...162..230W. doi:10.1126/science.162.3850.230. PMID 4877437.
- ^ MORTON, R. A.; GOODWIN, T. W. (1 April 1944). “Preparation of Retinene in Vitro”. Nature 153 (3883): 405–406. Bibcode: 1944Natur.153..405M. doi:10.1038/153405a0.
- ^ BALL, S; GOODWIN, TW; MORTON, RA (1946). “Retinene1-vitamin A aldehyde.”. The Biochemical Journal 40 (5–6): lix. PMID 20341217.
- ^ a b von Lintig, Johannes; Vogt, Klaus (2000). “Filling the Gap in Vitamin A Research: Molecular Identification of An Enzyme Cleaving Beta-carotene to Retinal”. Journal of Biological Chemistry 275 (16): 11915–11920. doi:10.1074/jbc.275.16.11915. PMID 10766819.
- ^ Woggon, Wolf-D. (2002). “Oxidative cleavage of carotenoids catalyzed by enzyme models and beta-carotene 15,15´-monooxygenase”. Pure and Applied Chemistry 74 (8): 1397–1408. doi:10.1351/pac200274081397.
- ^ Kim, Yeong-Su; Kim, Nam-Hee; Yeom, Soo-Jin; Kim, Seon-Won; Oh, Deok-Kun (2009). “In Vitro Characterization of a Recombinant Blh Protein from an Uncultured Marine Bacterium as a β-Carotene 15,15′-Dioxygenase”. Journal of Biological Chemistry 284 (23): 15781–93. doi:10.1074/jbc.M109.002618. PMC 2708875. PMID 19366683.
- ^ Lidén, Martin; Eriksson, Ulf (2006). “Understanding Retinol Metabolism: Structure and Function of Retinol Dehydrogenases”. Journal of Biological Chemistry 281 (19): 13001–13004. doi:10.1074/jbc.R500027200. PMID 16428379.
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- ^ Lin, Min; Zhang, Min; Abraham, Michael; Smith, Susan M.; Napoli, Joseph L. (2003). “Mouse Retinal Dehydrogenase 4 (RALDH4), Molecular Cloning, Cellular Expression, and Activity in 9-cis-Retinoic Acid Biosynthesis in Intact Cells”. Journal of Biological Chemistry 278 (11): 9856–9861. doi:10.1074/jbc.M211417200. PMID 12519776.
- ^ “KEGG ENZYME: 1.2.3.11 retinal oxidase”. 2009年3月10日閲覧。
- ^ Lamb, T D (1996). “Gain and kinetics of activation in the G-protein cascade of phototransduction”. Proceedings of the National Academy of Sciences 93 (2): 566–570. Bibcode: 1996PNAS...93..566L. doi:10.1073/pnas.93.2.566. PMC 40092. PMID 8570596.
- ^ Palczewski, Krzysztof; Kumasaka, Takashi; Hori, T; Behnke, CA; Motoshima, H; Fox, BA; Le Trong, I; Teller, DC et al. (2000). “Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor”. Science 289 (5480): 739–745. Bibcode: 2000Sci...289..739P. doi:10.1126/science.289.5480.739. PMID 10926528.
- ^ Seki, Takaharu; Isono, Kunio; Ito, Masayoshi; Katsuta, Yuko (1994). “Flies in the Group Cyclorrhapha Use (3S)-3-Hydroxyretinal as a Unique Visual Pigment Chromophore”. European Journal of Biochemistry 226 (2): 691–696. doi:10.1111/j.1432-1033.1994.tb20097.x. PMID 8001586.
- ^ Seki, Takaharu; Isono, Kunio; Ozaki, Kaoru; Tsukahara, Yasuo; Shibata-Katsuta, Yuko; Ito, Masayoshi; Irie, Toshiaki; Katagiri, Masanao (1998). “The metabolic pathway of visual pigment chromophore formation in Drosophila melanogaster: All-trans (3S)-3-hydroxyretinal is formed from all-trans retinal via (3R)-3-hydroxyretinal in the dark”. European Journal of Biochemistry 257 (2): 522–527. doi:10.1046/j.1432-1327.1998.2570522.x. PMID 9826202.
- ^ Moiseyev, Gennadiy; Chen, Ying; Takahashi, Yusuke; Wu, Bill X.; Ma, Jian-xing (2005). “RPE65 is the isomerohydrolase in the retinoid visual cycle”. Proceedings of the National Academy of Sciences 102 (35): 12413–12418. Bibcode: 2005PNAS..10212413M. doi:10.1073/pnas.0503460102. PMC 1194921. PMID 16116091.
- ^ Jin, Minghao; Yuan, Quan; Li, Songhua; Travis, Gabriel H. (2007). “Role of LRAT on the Retinoid Isomerase Activity and Membrane Association of Rpe65”. Journal of Biological Chemistry 282 (29): 20915–20924. doi:10.1074/jbc.M701432200. PMC 2747659. PMID 17504753.
- ^ Oberhauser, Vitus; Voolstra, Olaf; Bangert, Annette; von Lintig, Johannes; Vogt, Klaus (2008). “NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide”. Proceedings of the National Academy of Sciences 105 (48): 19000–5. Bibcode: 2008PNAS..10519000O. doi:10.1073/pnas.0807805105. PMC 2596218. PMID 19020100.
- ^ Chen, De-Liang; Wang, Guang-yu; Xu, Bing; Hu, Kun-Sheng (2002). “All-trans to 13-cis retinal isomerization in light-adapted bacteriorhodopsin at acidic pH”. Journal of Photochemistry and Photobiology B: Biology 66 (3): 188–194. doi:10.1016/S1011-1344(02)00245-2. PMID 11960728.
- ^ 1967 Nobel Prize in Medicine
[続きの解説]
「レチナール」の続きの解説一覧
- 1 レチナールとは
- 2 レチナールの概要
- 3 ビタミンA代謝
- 4 視覚
- 5 細菌ロドプシン
「レチナール」の例文・使い方・用例・文例
- レチナールのページへのリンク
