interleukin‐10とは？ わかりやすく解説

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インターロイキン10

英訳・(英)同義/類義語：interleukin 10, IL-10

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インターロイキン-10

(interleukin‐10 から転送)

出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2024/05/24 13:51 UTC 版)

インターロイキン-10（英: interleukin-10、略称: IL-10）またはCSIF（cytokine synthesis inhibitory factor）は、ヒトではIL10遺伝子にコードされるサイトカインである[5]。IL-10シグナルは、2分子のαサブユニット（英語版）と2分子のβサブユニット（英語版）からなるIL-10受容体（英語版）を介して伝達される[6]。IL-10の結合によってαサブユニットとβサブユニットの細胞質テールが、それぞれJAK1（英語版）、TYK2（英語版）によってリン酸化され、STAT3シグナルが誘導される[6]。


出典
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  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000016529 - Ensembl, May 2017
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  4. ^ Mouse PubMed Reference:
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