メロキシカム
メロキシカム
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2024/02/17 08:47 UTC 版)
メロキシカム(Meloxicam)は、鎮痛剤及び解熱剤の効果を持つ非ステロイド性抗炎症薬である。オキシカムの誘導体で、ピロキシカムと近い関係にあり、エノール型である[2]。ベーリンガーインゲルハイムが開発した。メロキシカムは、投与後、約30分から60分で痛みを緩和し始める[3]。
- ^ a b c d e Noble, S; Balfour, JA (March 1996). “Meloxicam.”. Drugs 51 (3): 424-30; discussion 431-32. doi:10.2165/00003495-199651030-00009. PMID 8882380.
- ^ a b “Meloxicam official FDA information, side effects, and uses”. Drugs.com (2010年3月). 2010年3月17日閲覧。
- ^ Auvinet, B; Ziller, R; Appelboom, T; Velicitat, P (November-December 1995). “Comparison of the onset and intensity of action of intramuscular meloxicam and oral meloxicam in patients with acute sciatica.”. Clinical Therapeutics 17 (6): 1078-98. doi:10.1016/0149-2918(95)80086-7. PMID 8750399.
- ^ Noble, S; Balfour, JA (Mar 1996). “Meloxicam”. Drugs 51 (3): 424-30; discussion 431-32. doi:10.2165/00003495-199651030-00007. PMID 8882380.
- ^ Engelhardt, G; Homma, D; Schlegel, K; Utzmann, R; Schnitzler, C (Oct 1995). “Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance”. Inflammation Research 44 (10): 423-433. doi:10.1007/BF01757699. PMID 8564518.
- ^ a b Hawkey, C; Kahan, A; Steinbru, K; Alegre, C; Baumelou, E; Begaud, B; Dequeker, J; Isomaki, H et al. (Sep 1998). “Gastrointestinal tolerability of meloxicam compared to diclofenac in osteoarthritis patients”. Rheumatology 37 (9): 937-945(9). doi:10.1093/rheumatology/37.9.937.
- ^ Dequeker, J; Hawkey, C; Kahan, A; Steinbruck, K; Alegre, C; Baumelou, E; Begaud, B; Isomaki, H et al. (1998). “Improvement in gastrointestinal tolerability of the selective cyclooxygenase (COX)-2 inhibitor, meloxicam, compared with piroxicam: results of the Safety and Efficacy Large-scale Evaluation of COX- inhibiting Therapies (SELECT) trial in osteoarthritis”. The British Journal of Rheumatology 37 (9): 946-51. doi:10.1093/rheumatology/37.9.946. PMID 9783758.
- ^ Wojtulewski, JA; Schattenkirchner, M; Barcelo, P; Le Loet, X; Bevis, PJR; Bluhmki, E; Distel, M. “A Six-Month Double-Blind Trial to Compare the Efficacy and Safety of Meloxicam 7.5 mg Daily and Naproxen 750 mg Daily in Patients with Rheumatoid Arthritis”. Rheumatology 35, Supplement 1: 22-8.
- ^ Singh, G; Lanes, S; Steinbru, G; Triadafilopoulos (2004). “Gastrointestinal tolerability of meloxicam compared to diclofenac in osteoarthritis patients”. Am J Med 117 (9): 100-6. PMID 15234645.
- ^ Off-label use discussed in: Arnold Plotnick MS, DVM, ACVIM, ABVP, Pain Management using Metacam, and Stein, Robert, Perioperative Pain Managemment Part IV, Looking Beyond Butorphanol, Sep 2006.
- ^ For off-label use example in rabbits, see Krempels, Dana, Hind Limb Paresis and Paralysis in Rabbits, University of Miami Biology Department.
- ^ US FDA Notice of Violation for off-label use promotion, April 2005.
- ^ “NADA 141-213: New Animal Drug Application Approval (for Metacam (meloxicam) 0.5 mg/mL and 1.5 mg/mL Oral Suspension)”. US Food and Drug Administration (2003年4月15日). 2010年7月24日閲覧。
- ^ Metacam Client Information Sheet, product description: "Non-steroidal anti-inflammatory drug for oral use in dogs only", and in the "What Is Metacam" section in bold-face type: "Do not use in cats.", January 2005.
- ^ Metacam 5 mg/mL Solution for Injection
- ^ Metacam 5 mg/mL Solution for Injection, Supplemental Approval October 28, 2004.
- ^ See the manufacturer's FAQ on its website, and its clinical dosing instructions for cats. Archived 2008年9月6日, at the Wayback Machine.
- ^ Discussion of Metacam use at persiancats.org in Metacam Risks In Cats, and at the consumer site metacamkills.com.
- ^ Merola, Valentina, DVM, DABT, and Dunayer Eric, MS, VMD, DABT, The 10 most common toxicoses in cats[リンク切れ], Toxicology Brief, Veterinary Medicine, pp. 340-342, June, 2006.
- 1 メロキシカムとは
- 2 メロキシカムの概要
- 3 家畜への使用
- 4 外部リンク
- メロキシカムのページへのリンク