PCNAとは？ わかりやすく解説

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米国企業情報
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ダウ・ジョーンズダウ・ジョーンズ

Publishing Co. of NA（NASDAQ:PCNA）

住所： 186 P.C.N.A. ParkwayLake Helen, FL 32744United States
電話： 1- (904) 228-1000
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ウィキペディア
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ウィキペディアウィキペディア

増殖細胞核抗原

(PCNA から転送)

出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/03/31 15:33 UTC 版)

増殖細胞核抗原（ぞうしょくさいぼうかくこうげん、英: proliferating cell nuclear antigen、略称: PCNA）は、真核生物細胞においてDNAポリメラーゼδ（英語版）のプロセシビティ（英語版）因子として作用するDNAクランプであり、DNA複製に必要不可欠である。PCNAはホモ三量体を形成し、DNAを取り囲むことでプロセシビティを高め、DNA複製、DNA修復、クロマチンリモデリング、エピジェネティクスに関与するタンパク質をリクルートするための足場として機能する[5]。


出典
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  4. ^ Mouse PubMed Reference:
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