コレラ毒素
コレラ毒素 [Cholera toxin,Choleragen,Cholera enterotoxin]
コレラ毒素
(choleratoxin から転送)
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2024/04/10 19:42 UTC 版)
コレラ毒素(コレラどくそ)またはコレラトキシン(英: cholera toxin、略称:CTX、Ctx、CT)は、コレラ菌Vibrio choleraeから分泌されるAB5型毒素である[1][2]。コレラ毒素は、コレラに特徴的な激しい水様便の原因となる[3]。易熱性エンテロトキシンファミリーに属する。
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- ^ Amberlyn M Wands; Akiko Fujita (October 2015). “Fucosylation and protein glycosylation create functional receptors for Cholera toxin”. eLife 4: e09545. doi:10.7554/eLife.09545. PMC 4686427. PMID 26512888 .
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- ^ Tsai, Billy; Rapoport, Tom A. (2002). “Unfolded cholera toxin is transferred to the ER membrane and released from protein disulfide isomerase upon oxidation by Ero1”. Journal of Cell Biology 159 (2): 207–216. doi:10.1083/jcb.200207120. PMC 2173060. PMID 12403808 .
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- ^ a b c d Davis, Brigid M; Waldor, Matthew K (2003-02-01). “Filamentous phages linked to virulence of Vibrio cholerae”. Current Opinion in Microbiology 6 (1): 35–42. doi:10.1016/S1369-5274(02)00005-X. ISSN 1369-5274 .
- ^ Pierre-Hervé Luppi. “The Discovery of Cholera-Toxin as a Powerful Neuroanatomical Tool”. 2011年3月23日閲覧。
- ^ “Cholera toxin regulates a signaling pathway critical for the expansion of neural stem cell cultures from the fetal and adult rodent brains”. PLOS ONE 5 (5): e10841. (2010). Bibcode: 2010PLoSO...510841A. doi:10.1371/journal.pone.0010841. PMC 2877108. PMID 20520777 .
- ^ a b Baldauf, Keegan; Royal, Joshua; Hamorsky, Krystal; Matoba, Nobuyuki (2015). “Cholera Toxin B: One Subunit with Many Pharmaceutical Applications”. Toxins 7 (3): 974–996. doi:10.3390/toxins7030974. PMC 4379537. PMID 25802972 .
- ^ a b c Kenworthy, Anne K.; Schmieder, Stefanie S.; Raghunathan, Krishnan; Tiwari, Ajit; Wang, Ting; Kelly, Christopher V.; Lencer, Wayne I. (2021). “Cholera Toxin as a Probe for Membrane Biology”. Toxins 13 (8): 543. doi:10.3390/toxins13080543. PMC 8402489. PMID 34437414 .
- 1 コレラ毒素とは
- 2 コレラ毒素の概要
- 3 応用
- 4 関連項目
- choleratoxinのページへのリンク