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タウタンパク質

(タウ・タンパク から転送)

出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/09/16 16:14 UTC 版)

タウタンパク質（タウタンパクしつ、英: Tau protein）は、微小管を安定化するタンパク質である。ギリシャ文字の τ（タウ）を用いて、τタンパク質と表記されることもある。タウタンパク質は中枢神経系の神経細胞に豊富に存在するが、他の部位では一般的ではない。中枢神経系のアストロサイトやオリゴデンドロサイトでも極めて低レベルで発現している[5]。アルツハイマー病やパーキンソン病[6]のような神経系の病理や認知症は、適切な微小管安定化能を失ったタウタンパク質と関係している。


出典
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000186868、ENSG00000276155、ENSG00000277956 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018411 - Ensembl, May 2017
  3. ^ Human PubMed Reference:
  4. ^ Mouse PubMed Reference:
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