天然変性タンパク質
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2021/03/20 10:26 UTC 版)
天然変性タンパク質(てんねんへんせいタンパクしつ、英: intrinsically disordered proteins、略称: IDP)とは、固定された、もしくは整った(「オーダーした」)三次元構造を持たないタンパク質である[2][3][4]。IDPは、完全に構造をとらない状態から部分的に構造をとる状態までをカバーし、ランダムコイルやモルテングロビュール、柔軟なリンカーで連結された複数ドメインタンパク質などが含まれる。IDPはタンパク質の主要なタイプの1つを構成する(ほかは球状タンパク質、線維状タンパク質、膜タンパク質)[5]。
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