GRIA2
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/04/22 05:56 UTC 版)
GRIA2またはGluA2、GluR2（glutamate ionotropic receptor AMPA type subunit 2、ionotropic glutamate receptor 2）は、ヒトではGRIA2遺伝子によってコードされるタンパク質である[5][6][7]。
- ^ a b c GRCh38: Ensembl release 89: ENSG00000120251 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033981 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
- ^ HGNC. “Symbol Report: GRIA2”. 2017年12月29日閲覧。
- ^ “Molecular cloning, chromosomal mapping, and functional expression of human brain glutamate receptors”. Proc Natl Acad Sci U S A 89 (4): 1443–7. (Mar 1992). doi:10.1073/pnas.89.4.1443. PMC 48467. PMID 1311100.
- ^ a b “Entrez Gene: GRIA2 glutamate receptor, ionotropic, AMPA 2”. 2020年11月2日閲覧。
- ^ “Interaction of the C-terminal domain of delta glutamate receptor with spectrin in the dendritic spines of cultured Purkinje cells”. Neurosci. Res. 34 (4): 281–7. (September 1999). doi:10.1016/S0168-0102(99)00061-9. PMID 10576550.
- ^ a b “The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs”. J. Biol. Chem. 277 (18): 15221–4. (May 2002). doi:10.1074/jbc.C200112200. PMID 11891216.
- ^ a b c d “Genetic manipulation of key determinants of ion flow in glutamate receptor channels in the mouse”. Brain Res. 907 (1–2): 233–43. (July 2001). doi:10.1016/S0006-8993(01)02445-3. PMID 11430906.
- ^ “Control of human potassium channel inactivation by editing of a small mRNA hairpin”. Nat. Struct. Mol. Biol. 11 (10): 950–6. (October 2004). doi:10.1038/nsmb825. PMID 15361858.
- ^ “Intron sequence directs RNA editing of the glutamate receptor subunit GluR2 coding sequence”. Proc. Natl. Acad. Sci. U.S.A. 91 (22): 10270–4. (October 1994). doi:10.1073/pnas.91.22.10270. PMC 45001. PMID 7937939.
- ^ a b “High abundance of GluR1 mRNA and reduced Q/R editing of GluR2 mRNA in individual NADPH-diaphorase neurons”. Mol. Cell. Neurosci. 17 (6): 1025–33. (June 2001). doi:10.1006/mcne.2001.0988. PMID 11414791.
- ^ Wahlstedt, Helene; Daniel, Chammiran; Ensterö, Mats; Ohman, Marie (2009-06). “Large-scale mRNA sequencing determines global regulation of RNA editing during brain development”. Genome Research 19 (6): 978–986. doi:10.1101/gr.089409.108. ISSN 1088-9051. PMC 2694479. PMID 19420382.
- ^ “RNA editing in brain controls a determinant of ion flow in glutamate-gated channels”. Cell 67 (1): 11–9. (October 1991). doi:10.1016/0092-8674(91)90568-J. PMID 1717158.
- ^ “Ca2+ permeability of unedited and edited versions of the kainate selective glutamate receptor GluR6”. Proc. Natl. Acad. Sci. U.S.A. 90 (2): 755–9. (January 1993). doi:10.1073/pnas.90.2.755. PMC 45744. PMID 7678465.
- ^ “RNA editing at arg607 controls AMPA receptor exit from the endoplasmic reticulum”. Neuron 34 (5): 759–72. (May 2002). doi:10.1016/S0896-6273(02)00693-1. PMID 12062022.
- ^ “From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS”. Nat. Rev. Neurosci. 2 (11): 806–19. (November 2001). doi:10.1038/35097565. PMID 11715057.
- ^ “Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients”. J. Neurol. Sci. 193 (2): 73–8. (January 2002). doi:10.1016/S0022-510X(01)00661-X. PMID 11790386.
- ^ “Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis”. J. Mol. Med. 83 (2): 110–20. (February 2005). doi:10.1007/s00109-004-0599-z. PMID 15624111.
- ^ “Glutamate receptors: RNA editing and death of motor neurons”. Nature 427 (6977): 801. (February 2004). doi:10.1038/427801a. PMID 14985749.
- ^ “Human spinal motoneurons express low relative abundance of GluR2 mRNA: an implication for excitotoxicity in ALS”. J. Neurochem. 85 (3): 680–9. (May 2003). doi:10.1046/j.1471-4159.2003.01703.x. PMID 12694394.
- ^ a b “Excitotoxicity and ALS: what is unique about the AMPA receptors expressed on spinal motor neurons?”. Amyotroph. Lateral Scler. Other Motor Neuron Disord. 6 (3): 131–44. (September 2005). doi:10.1080/14660820510037872. PMID 16183555.
- ^ “Underediting of glutamate receptor GluR-B mRNA in malignant gliomas”. Proc. Natl. Acad. Sci. U.S.A. 98 (25): 14687–92. (December 2001). doi:10.1073/pnas.251531398. PMC 64742. PMID 11717408.
- ^ Vivero, M; Doyle, L. A.; Fletcher, C. D.; Mertens, F; Hornick, J. L. (2014). “GRIA2 is a Novel Diagnostic Marker for Solitary Fibrous Tumour Identified through Gene Expression Profiling”. Histopathology 65 (1): 71–80. doi:10.1111/his.12377. PMID 24456377.
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