ETS1
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/09/25 07:15 UTC 版)
ETS1（C-ets-1）は、ヒトではETS1遺伝子にコードされるタンパク質である[5]。このタンパク質は転写因子のETSファミリーに属する[6]。
- ^ a b c GRCh38: Ensembl release 89: ENSG00000134954 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032035 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
- ^ “Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours”. Nature 359 (6391): 162–5. (Sep 1992). Bibcode: 1992Natur.359..162D. doi:10.1038/359162a0. PMID 1522903.
- ^ “Transcriptional regulation of telomerase activity: roles of the Ets transcription factor family”. Annals of the New York Academy of Sciences 1114 (1): 36–47. (Oct 2007). Bibcode: 2007NYASA1114...36D. doi:10.1196/annals.1396.022. PMID 17986575.
- ^ a b c “Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation”. Nucleic Acids Research 44 (8): 3567–85. (2016-05-05). doi:10.1093/nar/gkv1475. ISSN 0305-1048. PMC 4856961. PMID 26673693.
- ^ “Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway”. Trends Biochem. Sci. 23 (6): 213–6. (1998). doi:10.1016/S0968-0004(98)01211-0. PMID 9644975.
- ^ “EAPII interacts with ETS1 and modulates its transcriptional function”. Oncogene 22 (18): 2699–709. (May 2003). doi:10.1038/sj.onc.1206374. PMID 12743594.
- ^ “Modulation of ETS-1 transcriptional activity by huUBC9, a ubiquitin-conjugating enzyme”. Oncogene 15 (12): 1489–95. (Sep 1997). doi:10.1038/sj.onc.1201301. PMID 9333025.
- ^ “EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes”. Oncogene 19 (6): 745–53. (Feb 2000). doi:10.1038/sj.onc.1203385. PMID 10698492.
- ^ “Regulation of the human poly(ADP-ribose) polymerase promoter by the ETS transcription factor”. Oncogene 18 (27): 3954–62. (1999). doi:10.1038/sj.onc.1202778. PMID 10435618.
- ^ a b “Hypomethylation of ETS transcription factor binding sites and upregulation of PARP1 expression in endometrial cancer”. Biomed Res Int 2013: 946268. (2013). doi:10.1155/2013/946268. PMC 3666359. PMID 23762867.
- ^ “Oxidative DNA damage repair and parp 1 and parp 2 expression in Epstein-Barr virus-immortalized B lymphocyte cells from young subjects, old subjects, and centenarians”. Rejuvenation Res 10 (2): 191–204. (2007). doi:10.1089/rej.2006.0514. PMID 17518695.
- ^ “Role of the transcription factor Ets-1 in cisplatin resistance”. Mol. Cancer Ther. 3 (7): 823–32. (2004). PMID 15252143.
- ^ “Regulation of Ets function by protein - protein interactions”. Oncogene 19 (55): 6514–23. (2000). doi:10.1038/sj.onc.1204035. PMID 11175367.
- ^ a b c d “DNA-dependent protein kinase is a novel interaction partner for Ets-1 isoforms”. Biochem. Biophys. Res. Commun. 390 (3): 839–44. (2009). doi:10.1016/j.bbrc.2009.10.059. PMID 19836356.
- ^ “A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions”. J. Mol. Biol. 427 (8): 1655–69. (2015). doi:10.1016/j.jmb.2014.07.020. PMID 25083921.
- ^ “The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage”. PLOS ONE 8 (2): e55883. (2013). Bibcode: 2013PLoSO...855883L. doi:10.1371/journal.pone.0055883. PMC 3566071. PMID 23405229.
[続きの解説]
「ETS1」の続きの解説一覧
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