胼胝, べんち
線維症
(fibrosis から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2024/04/08 08:49 UTC 版)
線維症（せんいしょう、英: fibrosis、線維化とも）は、正常な実質組織が結合組織に置き換わる病理学的な創傷治癒過程である[1][2]。治癒過程が抑制されずに継続された場合、組織の大規模なリモデリングと永久的な瘢痕組織の形成が引き起こされる[1]。線維性瘢痕化（せんいせいはんこんか、英: fibrotic scarring）としても知られる。
- ^ a b c d Wynn, Thomas A. (2004). “Fibrotic disease and the TH1/TH2 paradigm”. Nature Reviews. Immunology (Springer Science and Business Media LLC) 4 (8): 583–594. doi:10.1038/nri1412. ISSN 1474-1733. PMC 2702150. PMID 15286725.
- ^ Birbrair, Alexander; Zhang, Tan; Files, Daniel C.; Mannava, Sandeep; Smith, Thomas; Wang, Zhong-Min; Messi, Maria L.; Mintz, Akiva et al. (2014-11-06). “Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner” (英語). Stem Cell Research & Therapy 5 (6): 122. doi:10.1186/scrt512. ISSN 1757-6512. PMC 4445991. PMID 25376879.
- ^ Glossary of dermatopathological terms. DermNet NZ
- ^ a b “Epigenetics and the overhealing wound: the role of DNA methylation in fibrosis”. Fibrogenesis & Tissue Repair 8: 18. (2015). doi:10.1186/s13069-015-0035-8. PMC 4591063. PMID 26435749.
- ^ “Dual mTOR Inhibition Is Required to Prevent TGF-β-Mediated Fibrosis: Implications for Scleroderma.”. J Invest Dermatol 135 (11): 2873–6. (2015). doi:10.1038/jid.2015.252. PMC 4640976. PMID 26134944.
- ^ “TGF-beta signaling and the fibrotic response”. FASEB Journal 18 (7): 816–827. (2004). doi:10.1096/fj.03-1273rev. PMID 15117886.
- ^ dwivedi, durgesh Kumar; Jena, Gopa Bandhu (Nov 2018). “Glibenclamide protects against thioacetamide-induced hepatic damage in Wistar rat: investigation on NLRP3, MMP-2, and stellate cell activation”. Naunyn-Schmiedeberg's Archives of Pharmacology 391 (11): 1257–1274. doi:10.1007/s00210-018-1540-2. PMID 30066023.
- ^ Chute, Michael; Aujla, Preetinder; Jana, Sayantan; Kassiri, Zamaneh (2019). “The Non-Fibrillar Side of Fibrosis: Contribution of the Basement Membrane, Proteoglycans, and Glycoproteins to Myocardial Fibrosis”. Journal of Cardiovascular Development and Disease 6 (4): 35. doi:10.3390/jcdd6040035. ISSN 2308-3425. PMC 6956278. PMID 31547598.
- ^ Duffield JS (June 2014). “Cellular and molecular mechanisms in kidney fibrosis”. J Clin Invest 124 (6): 2299–306. doi:10.1172/JCI72267. PMC 4038570. PMID 24892703.
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