Hippoシグナル伝達経路
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2021/04/25 04:29 UTC 版)
Hippoシグナル伝達経路（Hippoシグナルでんたつけいろ、英: Hippo signaling pathway）またはSalvador-Warts-Hippo（SWH） 経路（Salvador-Warts-Hippoけいろ）は、動物において、細胞増殖とアポトーシスの調節を通じて器官のサイズを制御するシグナル伝達経路である。この経路の名称は、ショウジョウバエDrosphilaで重要なシグナル伝達因子の1つであるプロテインキナーゼHippo（Hpo）に由来する。Hippoをコードする遺伝子の変異は組織の過成長をもたらし、カバのような（hippopotamus-like）表現型をもたらす。
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[続きの解説]
「Hippoシグナル伝達経路」の続きの解説一覧
- 1 Hippoシグナル伝達経路とは
- 2 Hippoシグナル伝達経路の概要
- 3 ヒトの器官のサイズの調節
- 4 関連文献
- Hippoシグナル伝達経路のページへのリンク
