代替酸化酵素
(オルタナティブオキシダーゼ から転送)
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2017/07/29 22:57 UTC 版)
代替酸化酵素(だいたいさんかこうそ、alternative oxidase (AOX)、オルタナティブオキシダーゼ)は、様々な真核生物においてミトコンドリア電子伝達系を構成する酵素の1つである[1][2]。そのホモログは原核生物のゲノム中にも見出されている[3][4]。
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- ^ McDonald A, Vanlerberghe G (2004). “Branched mitochondrial electron transport in the Animalia: presence of alternative oxidase in several animal phyla”. IUBMB Life 56 (6): 333–41. doi:10.1080/1521-6540400000876. PMID 15370881.
- ^ Sluse FE, Jarmuszkiewicz W (1998). “Alternative oxidase in the branched mitochondrial respiratory network: an overview on structure, function, regulation, and role”. Braz. J. Med. Biol. Res. 31 (6): 733–47. doi:10.1590/S0100-879X1998000600003. PMID 9698817.
- ^ McDonald AE, Amirsadeghi S, Vanlerberghe GC (2003). “Prokaryotic orthologues of mitochondrial alternative oxidase and plastid terminal oxidase”. Plant Mol. Biol. 53 (6): 865–76. doi:10.1023/B:PLAN.0000023669.79465.d2. PMID 15082931.
- ^ Atteia A, van Lis R, van Hellemond JJ, Tielens AG, Martin W, Henze K (2004). “Identification of prokaryotic homologues indicates an endosymbiotic origin for the alternative oxidases of mitochondria (AOX) and chloroplasts (PTOX)”. Gene 330: 143–8. doi:10.1016/j.gene.2004.01.015. PMID 15087133.
- ^ Moore AL, Siedow JN (1991). “The regulation and nature of the cyanide-resistant alternative oxidase of plant mitochondria”. Biochim. Biophys. Acta 1059 (2): 121–40. doi:10.1016/S0005-2728(05)80197-5. PMID 1883834.
- ^ Vanlerberghe GC, McIntosh L (1997). “Alternative oxidase: From Gene to Function”. Annual Review of Plant Physiology and Plant Molecular Biology 48: 703–734. doi:10.1146/annurev.arplant.48.1.703. PMID 15012279.
- ^ Ito Y, Saisho D, Nakazono M, Tsutsumi N, Hirai A (1997). “Transcript levels of tandem-arranged alternative oxidase genes in rice are increased by low temperature”. Gene 203 (2): 121–9. doi:10.1016/S0378-1119(97)00502-7. PMID 9426242.
- ^ Maxwell DP, Wang Y, McIntosh L (1999). “The alternative oxidase lowers mitochondrial reactive oxygen production in plant cells”. Proc. Natl. Acad. Sci. U.S.A. 96 (14): 8271–6. doi:10.1073/pnas.96.14.8271. PMC 22224. PMID 10393984 .
- ^ Chaudhuri M, Ott RD, Hill GC (2006). “Trypanosome alternative oxidase: from molecule to function”. Trends Parasitol. 22 (10): 484–91. doi:10.1016/j.pt.2006.08.007. PMID 16920028.
- ^ Clarkson AB, Bienen EJ, Pollakis G, Grady RW (1989). “Respiration of bloodstream forms of the parasite Trypanosoma brucei brucei is dependent on a plant-like alternative oxidase”. J. Biol. Chem. 264 (30): 17770–6. PMID 2808350 .
- ^ Nihei C, Fukai Y, Kita K (2002). “Trypanosome alternative oxidase as a target of chemotherapy”. Biochim. Biophys. Acta 1587 (2-3): 234–9. doi:10.1016/s0925-4439(02)00086-8. PMID 12084465.
- ^ Grady RW, Bienen EJ, Dieck HA, Saric M, Clarkson AB (1993). “N-n-alkyl-3,4-dihydroxybenzamides as inhibitors of the trypanosome alternative oxidase: activity in vitro and in vivo”. Antimicrob. Agents Chemother. 37 (5): 1082–5. doi:10.1128/aac.37.5.1082. PMC 187903. PMID 8517695 .
- ^ Minagawa N, Yabu Y, Kita K, Nagai K, Ohta N, Meguro K, Sakajo S, Yoshimoto A (1997). “An antibiotic, ascofuranone, specifically inhibits respiration and in vitro growth of long slender bloodstream forms of Trypanosoma brucei brucei”. Mol. Biochem. Parasitol. 84 (2): 271–80. doi:10.1016/S0166-6851(96)02797-1. PMID 9084049.
- ^ Yabu Y, Yoshida A, Suzuki T, Nihei C, Kawai K, Minagawa N, Hosokawa T, Nagai K, Kita K, Ohta N (2003). “The efficacy of ascofuranone in a consecutive treatment on Trypanosoma brucei brucei in mice”. Parasitol. Int. 52 (2): 155–64. doi:10.1016/S1383-5769(03)00012-6. PMID 12798927.
- ^ Miguez M, Reeve C, Wood PM, Hollomon DW (2004). “Alternative oxidase reduces the sensitivity of Mycosphaerella graminicola to QOI fungicides”. Pest Manag. Sci. 60 (1): 3–7. doi:10.1002/ps.837. PMID 14727735.
- ^ Avila-Adame C, Köller W (2003). “Impact of alternative respiration and target-site mutations on responses of germinating conidia of Magnaporthe grisea to Qo-inhibiting fungicides”. Pest Manag. Sci. 59 (3): 303–9. doi:10.1002/ps.638. PMID 12639047.
- ^ Berthold DA, Stenmark P (2003). “Membrane-bound diiron carboxylate proteins”. Annual review of plant biology 54: 497–517. doi:10.1146/annurev.arplant.54.031902.134915. PMID 14503001.
- ^ Berthold DA, Andersson ME, Nordlund P (2000). “New insight into the structure and function of the alternative oxidase”. Biochim. Biophys. Acta 1460 (2-3): 241–54. doi:10.1016/S0005-2728(00)00149-3. PMID 11106766.
- ^ Berthold DA, Voevodskaya N, Stenmark P, Gräslund A, Nordlund P (2002). “EPR studies of the mitochondrial alternative oxidase. Evidence for a diiron carboxylate center”. J. Biol. Chem. 277 (46): 43608–14. doi:10.1074/jbc.M206724200. PMID 12215444 .
- ^ Affourtit C, Albury MS, Crichton PG, Moore AL (2002). “Exploring the molecular nature of alternative oxidase regulation and catalysis”. FEBS Lett. 510 (3): 121–6. doi:10.1016/S0014-5793(01)03261-6. PMID 11801238.
- 1 代替酸化酵素とは
- 2 代替酸化酵素の概要
- 3 関連項目
- 代替酸化酵素のページへのリンク