カテニン
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/06/12 01:15 UTC 版)
カテニン（英: catenin）は、動物細胞でカドヘリン細胞接着分子と複合体を形成するタンパク質のファミリーである。最初に同定された2種類のカテニン[2]は、α-カテニン、β-カテニンとして知られている。α-カテニンはβ-カテニンと結合し、またアクチンフィラメント（F-アクチン）とも結合することができる[3]。β-カテニンは古典的（クラシカル）カドヘリンの細胞質テールに直接結合する。γ-カテニンやδ-カテニンなど、その他のカテニンも同定されている。「カテニン」（catenin）という名称はラテン語で「鎖」を意味する'catena'に由来し、カドヘリンと細胞骨格を連結すると考えられていたためこの名称がつけられた[4]。
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- ^ Song S, Christova T, Perusini S, Alizadeh S, Bao RY, Miller BW, Hurren R, Jitkova Y, Gronda M, Isaac M, Joseph B, Subramaniam R, Aman A, Chau A, Hogge DE, Weir SJ, Kasper J, Schimmer AD, Al-awar R, Wrana JL, Attisano L (December 2011). “Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers”. Cancer Res. 71 (24): 7628–39. doi:10.1158/0008-5472.CAN-11-2745. PMID 22009536.
- ^ Nam JS, Ino Y, Sakamoto M, Hirohashi S (September 2002). “Ras farnesylation inhibitor FTI-277 restores the E-cadherin/catenin cell adhesion system in human cancer cells and reduces cancer metastasis”. Jpn. J. Cancer Res. 93 (9): 1020–8. doi:10.1111/j.1349-7006.2002.tb02479.x. PMC 5927130. PMID 12359056.
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[続きの解説]
「カテニン」の例文・使い方・用例・文例
- カテニンのページへのリンク
