DNMT3A
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2020/12/05 09:12 UTC 版)
DNMT3A（DNA (cytosine-5)-methyltransferase 3A）は、DNA中の特定のCpG配列のシトシンに対するメチル基の転移を触媒する酵素であり、ヒトではDNMT3A遺伝子にコードされる[5][6]。この過程はDNAメチル化と呼ばれる。
- ^ a b c GRCh38: Ensembl release 89: ENSG00000119772 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020661 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
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- ^ a b “Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription”. The EMBO Journal 20 (10): 2536–44. (May 2001). doi:10.1093/emboj/20.10.2536. PMC: 125250. PMID 11350943.
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- ^ a b “Dnmt3a - DNA methyltransferase 3A | International Mouse Phenotyping Consortium”. www.mousephenotype.org. 2020年3月16日閲覧。
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- ^ a b “3i Consortium - Wellcome Trust Sanger Institute”. www.immunophenotype.org. 2020年3月16日閲覧。
[続きの解説]
「DNMT3A」の続きの解説一覧
- 1 DNMT3Aとは
- 2 DNMT3Aの概要
- 3 遺伝子
- 4 臨床的意義
- 5 関連文献
- DNMT3Aのページへのリンク
