キチナーゼ
キチナーゼ
(Chitinase から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2020/03/18 05:17 UTC 版)
キチナーゼ(Chitinase、EC 3.2.1.14)は、キチンのグリコシド結合を分解する加水分解酵素である[1]。キチンは菌の細胞壁及びいくつかの種の動物（蠕虫、節足動物）の外骨格を形成する成分であるため、キチナーゼは自身のキチンを再構成する必要のある生物か[2]、菌または動物のキチンを消化する必要のある生物が持つ。
- ^ Jolles P, Muzzarelli RAA (1999). Chitin and Chitinases. Basel: Birkhauser. ISBN 3-7643-5815-7.
- ^ Sami L, Pusztahelyi T, Emri T, Varecza Z, Fekete A, Grallert A, Karanyi Z, Kiss L, Pocsi I (August 2001). “Autolysis and aging of Penicillium chrysogenum cultures under carbon starvation: Chitinase production and antifungal effect of allosamidin”. The Journal of General and Applied Microbiology 47 (4): 201?211. doi:10.2323/jgam.47.201. PMID 12483620.
- ^ Hunt DE, Gevers D, Vahora NM, Polz MF (January 2008). “Conservation of the Chitin Utilization Pathway in the Vibrionaceae”. Applied and Environmental Microbiology 74 (1): 44?51. doi:10.1128/AEM.01412-07. PMC: 2223224. PMID 17933912.
- ^ Xiao X, Yin X, Lin J, Sun L, You Z, Wang P, Wang F (December 2005). “Chitinase Genes in Lake Sediments of Ardley Island, Antarctica”. Applied and Environmental Microbiology 71 (12): 7904?9. doi:10.1128/AEM.71.12.7904-7909.2005. PMC: 1317360. PMID 16332766.
- ^ Salzer P, Bonanomi A, Beyer K, Vogeli-Lange R, Aeschbacher RA, Lange J, Wiemken A, Kim D, Cook DR, Boller T (July 2000). “Differential expression of eight chitinase genes in Medicago truncatula roots during mycorrhiza formation, nodulation, and pathogen infection”. Molecular Plant-Microbe Interactions : MPMI 13 (7): 763?77. doi:10.1094/MPMI.2000.13.7.763. PMID 10875337.
- ^ Eurich, K; et al. (2009 Nov). “Potential role of chitinase 3-like-1 in inflammation-associated carcinogenic changes of epithelial cells.”. World J Gastroenterol 15 (42): 5249?5259. PMC: 2776850. PMID 19908331.
- ^ Akaki C, Duke GE (2005). “Apparent chitin digestibilities in the Eastern screech owl (Otus asio) and the American kestrel (Falco sparverius)”. Journal of Experimental Zoology 283 (4?5): 387?393. doi:10.1002/(SICI)1097-010X(19990301/01)283:4/5<387::AID-JEZ8>3.0.CO;2-W.
- ^ Gutowska MA, Drazen JC, Robison BH (November 2004). “Digestive chitinolytic activity in marine fishes of Monterey Bay, California”. Comparative biochemistry and physiology. Part A, Molecular & Integrative Physiology 139 (3): 351?8. doi:10.1016/j.cbpb.2004.09.020. PMID 15556391.
- ^ Paoletti MG, Norberto L, Damini R, Musumeci S (2007). “Human gastric juice contains chitinase that can degrade chitin”. Annals of Nutrition & Metabolism 51 (3): 244?51. doi:10.1159/000104144. PMID 17587796.
- ^ Renkema GH, Boot RG, Muijsers AO, Donker-Koopman WE, Aerts JM (February 1995). “Purification and Characterization of Human Chitotriosidase, a Novel Member of the Chitinase Family of Proteins”. The Journal of Biological Chemistry 270 (5): 2198?202. doi:10.1074/jbc.270.5.2198. PMID 7836450.
- ^ a b Escott GM, Adams DJ (December 1995). “Chitinase activity in human serum and leukocytes”. Infection and Immunity 63 (12): 4770?3. PMC: 173683. PMID 7591134.
- ^ Hakala BE, White C, Recklies AD (1993). “Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family”. The Journal of Biological Chemistry 268 (34): 25803?25810. PMID 8245017.
- ^ Recklies AD, White C, Ling H (July 2002). “The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways”. The Biochemical Journal 365 (Pt 1): 119?26. doi:10.1042/BJ20020075. PMC: 1222662. PMID 12071845.
- ^ van Eijk M, van Roomen CPAA, Renkema GH, Bussink AP, Andrews L, Blommaart EFC, Sugar A, Verhoeven AJ, Boot RG, Aerts JMFG (2005). “Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity”. International Immunology 17 (11): 1505?1512. doi:10.1093/intimm/dxh328. PMID 16214810.
- ^ Bierbaum S, Nickel R, Koch A, Lau S, Deichmann KA, Wahn U, Superti-Furga A, Heinzmann A (December 2005). “Polymorphisms and Haplotypes of Acid Mammalian Chitinase Are Associated with Bronchial Asthma”. American Journal of Respiratory and Critical Care Medicine 172 (12): 1505?9. doi:10.1164/rccm.200506-890OC. PMC: 2718453. PMID 16179638.
- ^ Zhao J, Zhu H, Wong CH, Leung KY, Wong WS (July 2005). “Increased lungkine and chitinase levels in allergic airway inflammation: a proteomics approach”. Proteomics 5 (11): 2799?807. doi:10.1002/pmic.200401169. PMID 15996009.
- ^ Elias JA, Homer RJ, Hamid Q, Lee CG (September 2005). “Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma”. The Journal of Allergy and Clinical Immunology 116 (3): 497?500. doi:10.1016/j.jaci.2005.06.028. PMID 16159614.
- ^ Zhu Z, Zheng T, Homer RJ, Kim YK, Chen NY, Cohn L, Hamid Q, Elias JA (June 2004). “Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation”. Science 304 (5677): 1678?82. doi:10.1126/science.1095336. PMID 15192232.
- ^ Chupp GL, Lee CG, Jarjour N, Shim YM, Holm CT, He S, Dziura JD, Reed J, Coyle AJ, Kiener P, Cullen M, Grandsaigne M, Dombret MC, Aubier M, Pretolani M, Elias JA (2005). “A Chitinase-like Protein in the Lung and Circulation of Patients with Severe Asthma”. The New England Journal of Medicine 357 (20): 2016?2027. doi:10.1056/NEJMoa073600. PMID 18003958.
- ^ Maizels RM (December 2005). “Infections and allergy ? helminths, hygiene and host immune regulation”. Current Opinion in Immunology 17 (6): 656?61. doi:10.1016/j.coi.2005.09.001. PMID 16202576.
- ^ Hunter MM, McKay DM (January 2004). “Review article: helminths as therapeutic agents for inflammatory bowel disease”. Alimentary Pharmacology & Therapeutics 19 (2): 167?77. doi:10.1111/j.0269-2813.2004.01803.x. PMID 14723608.
- ^ Palmas C, Gabriele F, Conchedda M, Bortoletti G, Ecca AR (June 2003). “Causality or coincidence: may the slow disappearance of helminths be responsible for the imbalances in immune control mechanisms?”. Journal of Helminthology 77 (2): 147?53. doi:10.1079/JOH2003176. PMID 12756068.
- ^ Feingold BF (March 1975). “Food additives in clinical medicine”. International Journal of Dermatology 14 (2): 112?4. doi:10.1111/j.1365-4362.1975.tb01426.x. PMID 1123257.
- ^ 古賀大三「植物キチナーゼと生体防御」『化学と生物』第32巻第11号、日本農芸化学会、1994年、 712-722頁、 doi:10.1271/kagakutoseibutsu1962.32.712、2016年2月6日閲覧。
[続きの解説]
「キチナーゼ」の続きの解説一覧
- 1 キチナーゼとは
- 2 キチナーゼの概要
- 3 食物中の存在
- Chitinaseのページへのリンク
