後期促進複合体
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2021/02/27 08:30 UTC 版)
後期促進複合体(こうきそくしんふくごうたい、英: anaphase-promoting complex)は、細胞周期タンパク質に26Sプロテアソームによる分解の目印を付けるE3ユビキチンリガーゼである。サイクロソーム(cyclosome)とも呼ばれ、APC/Cと略されることが多い。APC/Cは11から13のサブユニットからなるタンパク質で、Cullinサブユニット(Apc2)とRINGサブユニット(Apc11)といった、SCF複合体と類似した触媒サブユニットが含まれている。APC/Cの他の部分の機能は不明点が多いが、高度に保存されている[1]。
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