Protein Complexとは? わかりやすく解説

Weblio 辞書 > 辞書・百科事典 > 百科事典 > Protein Complexの意味・解説 

タンパク質複合体

(Protein Complex から転送)

出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2024/04/08 09:17 UTC 版)

タンパク質複合体(英語: protein complex)または多タンパク質複合体(英語: multiprotein complex)は、2つ以上の関連するポリペプチド鎖のグループである。異なるポリペプチド鎖は、異なる機能を持っている場合がある。これは、単一のポリペプチド鎖に複数の触媒ドメインが見られる多酵素複合体英語版とは異なる[1]


  1. ^ Price NC, Stevens L (1999). Fundamentals of enzymology: The cell and molecular biology of catalytic protein. Oxford ; New York: Oxford University Press. ISBN 0-19-850229-X 
  2. ^ Hartwell LH, Hopfield JJ, Leibler S, Murray AW (December 1999). “From molecular to modular cell biology”. Nature 402 (6761 Suppl): C47–52. doi:10.1038/35011540. PMID 10591225. 
  3. ^ Pereira-Leal JB, Levy ED, Teichmann SA (March 2006). “The origins and evolution of functional modules: lessons from protein complexes”. Philos. Trans. R. Soc. Lond. B Biol. Sci. 361 (1467): 507–17. doi:10.1098/rstb.2005.1807. PMC 1609335. PMID 16524839. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609335/. 
  4. ^ a b c Amoutzias G, Van de Peer Y (2010). “Single-Gene and Whole-Genome Duplications and the Evolution of Protein–Protein Interaction Networks. Evolutionary genomics and systems biology”. In Caetano-Anolles, Gustavo. Evolutionary Genomics. pp. 413–429. doi:10.1002/9780470570418.ch19 
  5. ^ Nooren IM, Thornton JM (July 2003). “Diversity of protein interactions”. EMBO J. 22 (14): 3486–92. doi:10.1093/emboj/cdg359. PMC 165629. PMID 12853464. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165629/. 
  6. ^ Brown KR, Jurisica I (2007). “Unequal evolutionary conservation of human protein interactions in interologous networks”. Genome Biol. 8 (5): R95. doi:10.1186/gb-2007-8-5-r95. PMC 1929159. PMID 17535438. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929159/. 
  7. ^ Tompa P, Fuxreiter M (January 2008). “Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions”. Trends Biochem. Sci. 33 (1): 2–8. doi:10.1016/j.tibs.2007.10.003. PMID 18054235. 
  8. ^ Fuxreiter M (January 2012). “Fuzziness: linking regulation to protein dynamics”. Mol Biosyst 8 (1): 168–77. doi:10.1039/c1mb05234a. PMID 21927770. 
  9. ^ Fuxreiter M, Simon I, Bondos S (August 2011). “Dynamic protein-DNA recognition: beyond what can be seen”. Trends Biochem. Sci. 36 (8): 415–23. doi:10.1016/j.tibs.2011.04.006. PMID 21620710. 
  10. ^ a b c Ryan, C. J.; Krogan, N. J.; Cunningham, P; Cagney, G (2013). “All or nothing: Protein complexes flip essentiality between distantly related eukaryotes”. Genome Biology and Evolution 5 (6): 1049–59. doi:10.1093/gbe/evt074. PMC 3698920. PMID 23661563. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698920/. 
  11. ^ Jeong, H; Mason, S. P.; Barabási, A. L.; Oltvai, Z. N. (2001). “Lethality and centrality in protein networks”. Nature 411 (6833): 41–2. arXiv:cond-mat/0105306. Bibcode2001Natur.411...41J. doi:10.1038/35075138. PMID 11333967. 
  12. ^ Yu, H; Braun, P; Yildirim, M. A.; Lemmens, I; Venkatesan, K; Sahalie, J; Hirozane-Kishikawa, T; Gebreab, F et al. (2008). “High-quality binary protein interaction map of the yeast interactome network”. Science 322 (5898): 104–10. Bibcode2008Sci...322..104Y. doi:10.1126/science.1158684. PMC 2746753. PMID 18719252. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746753/. 
  13. ^ Zotenko, E; Mestre, J; O'Leary, D. P.; Przytycka, T. M. (2008). “Why do hubs in the yeast protein interaction network tend to be essential: Reexamining the connection between the network topology and essentiality”. PLOS Computational Biology 4 (8): e1000140. Bibcode2008PLSCB...4E0140Z. doi:10.1371/journal.pcbi.1000140. PMC 2467474. PMID 18670624. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2467474/. 
  14. ^ a b Hart, G. T.; Lee, I; Marcotte, E. R. (2007). “A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality”. BMC Bioinformatics 8: 236. doi:10.1186/1471-2105-8-236. PMC 1940025. PMID 17605818. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940025/. 
  15. ^ Wang, H; Kakaradov, B; Collins, S. R.; Karotki, L; Fiedler, D; Shales, M; Shokat, K. M.; Walther, T. C. et al. (2009). “A complex-based reconstruction of the Saccharomyces cerevisiae interactome”. Molecular & Cellular Proteomics 8 (6): 1361–81. doi:10.1074/mcp.M800490-MCP200. PMC 2690481. PMID 19176519. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690481/. 
  16. ^ Fraser, H. B.; Plotkin, J. B. (2007). “Using protein complexes to predict phenotypic effects of gene mutation”. Genome Biology 8 (11): R252. doi:10.1186/gb-2007-8-11-r252. PMC 2258176. PMID 18042286. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258176/. 
  17. ^ Lage, K; Karlberg, E. O.; Størling, Z. M.; Olason, P. I.; Pedersen, A. G.; Rigina, O; Hinsby, A. M.; Tümer, Z et al. (2007). “A human phenome-interactome network of protein complexes implicated in genetic disorders”. Nature Biotechnology 25 (3): 309–16. doi:10.1038/nbt1295. PMID 17344885. 
  18. ^ Oti, M; Brunner, H. G. (2007). “The modular nature of genetic diseases”. Clinical Genetics 71 (1): 1–11. doi:10.1111/j.1399-0004.2006.00708.x. PMID 17204041. 
  19. ^ Hashimoto K, Nishi H, Bryant S, Panchenko AR (June 2011). “Caught in self-interaction: evolutionary and functional mechanisms of protein homooligomerization”. Phys Biol 8 (3): 035007. Bibcode2011PhBio...8c5007H. doi:10.1088/1478-3975/8/3/035007. PMC 3148176. PMID 21572178. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148176/. 
  20. ^ Bernstein H, Edgar RS, Denhardt GH. Intragenic complementation among temperature sensitive mutants of bacteriophage T4D. Genetics. 1965;51(6):987-1002.
  21. ^ Smallwood S, Cevik B, Moyer SA. Intragenic complementation and oligomerization of the L subunit of the sendai virus RNA polymerase. Virology. 2002;304(2):235-245. doi:10.1006/viro.2002.1720
  22. ^ Rodríguez-Pombo P, Pérez-Cerdá C, Pérez B, Desviat LR, Sánchez-Pulido L, Ugarte M. Towards a model to explain the intragenic complementation in the heteromultimeric protein propionyl-CoA carboxylase. Biochim Biophys Acta. 2005;1740(3):489-498. doi:10.1016/j.bbadis.2004.10.009
  23. ^ Crick FH, Orgel LE. The theory of inter-allelic complementation. J Mol Biol. 1964 Jan;8:161-5. doi: 10.1016/s0022-2836(64)80156-x. PMID 14149958
  24. ^ Jehle H. Intermolecular forces and biological specificity. Proc Natl Acad Sci U S A. 1963;50(3):516-524. doi:10.1073/pnas.50.3.516
  25. ^ Raicu V, Stoneman MR, Fung R, Melnichuk M, Jansma DB, Pisterzi LF, Rath S, Fox, M, Wells, JW, Saldin DK (2008). “Determination of supramolecular structure and spatial distribution of protein complexes in living cells.”. Nature Photonics 3 (2): 107–113. doi:10.1038/nphoton.2008.291. 
  26. ^ Dobson, Christopher M (December 2003). “Protein folding and misfolding”. Nature 426 (6968): 884–90. Bibcode2003Natur.426..884D. doi:10.1038/nature02261. PMID 14685248. 
  27. ^ a b Marsh JA, Hernández H, Hall Z, Ahnert SE, Perica T, Robinson CV, Teichmann SA (Apr 2013). “Protein complexes are under evolutionary selection to assemble via ordered pathways”. Cell 153 (2): 461–470. doi:10.1016/j.cell.2013.02.044. PMC 4009401. PMID 23582331. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009401/. 
  28. ^ Sudha, Govindarajan; Nussinov, Ruth; Srinivasan, Narayanaswamy (2014). “An overview of recent advances in structural bioinformatics of protein-protein interactions and a guide to their principles”. Progress in Biophysics and Molecular Biology 116 (2–3): 141–50. doi:10.1016/j.pbiomolbio.2014.07.004. PMID 25077409. 
  29. ^ Marsh, Joseph; Teichmann, Sarah A (May 2014). “Protein flexibility facilitates quaternary structure assembly and evolution”. PLOS Biology 12 (5): e1001870. doi:10.1371/journal.pbio.1001870. PMC 4035275. PMID 24866000. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035275/. 
  30. ^ Levy, Emmanuel D; Boeri Erba, Elisabetta; Robinson, Carol V; Teichmann, Sarah A (July 2008). “Assembly reflects evolution of protein complexes”. Nature 453 (7199): 1262–5. Bibcode2008Natur.453.1262L. doi:10.1038/nature06942. PMC 2658002. PMID 18563089. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658002/. 
  31. ^ Marsh JA, Hernández H, Hall Z, Ahnert SE, Perica T, Robinson CV, Teichmann SA (Apr 2013). “Protein complexes are under evolutionary selection to assemble via ordered pathways”. Cell 153 (2): 461–470. doi:10.1016/j.cell.2013.02.044. PMC 4009401. PMID 23582331. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4009401/. 


「タンパク質複合体」の続きの解説一覧



英和和英テキスト翻訳>> Weblio翻訳
英語⇒日本語日本語⇒英語
  
  •  Protein Complexのページへのリンク

辞書ショートカット

すべての辞書の索引

「Protein Complex」の関連用語

Protein Complexのお隣キーワード
検索ランキング

   

英語⇒日本語
日本語⇒英語
   



Protein Complexのページの著作権
Weblio 辞書 情報提供元は 参加元一覧 にて確認できます。

   
ウィキペディアウィキペディア
All text is available under the terms of the GNU Free Documentation License.
この記事は、ウィキペディアのタンパク質複合体 (改訂履歴)の記事を複製、再配布したものにあたり、GNU Free Documentation Licenseというライセンスの下で提供されています。 Weblio辞書に掲載されているウィキペディアの記事も、全てGNU Free Documentation Licenseの元に提供されております。

©2024 GRAS Group, Inc.RSS