基底小体
基底小体
(Basal body から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2021/02/10 16:14 UTC 版)
基底小体（きていしょうたい、英: basal body, basal granule）またはキネトソーム（英: kinetosome）は、真核生物の波動毛（繊毛または鞭毛）の基底部に存在するタンパク質構造である。中心小体といくつかの付属的なタンパク質構造から形成され、本質的には中心小体に変化が加えられたものである[1][2]。基底小体は、軸糸の微小管の伸長のための核形成部位として機能する。基底小体の由来となる中心小体は、微小管を中心体に固定するタンパク質の固定点の役割を果たし、微小管形成中心（MTOC）として知られる。これらの微小管は多くの真核細胞内で小胞や細胞小器官に構造的足場を提供したり移動を助けたりしている。
- ^ Schrøder, Jacob M.; Larsen, Jesper; Komarova, Yulia; Akhmanova, Anna; Thorsteinsson, Rikke I.; Grigoriev, Ilya; Manguso, Robert; Christensen, Søren T. et al. (2011-08-01). “EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms”. Journal of Cell Science 124 (Pt 15): 2539–2551. doi:10.1242/jcs.085852. ISSN 1477-9137. PMC: 3138699. PMID 21768326.
- ^ Benjamin Lewin (2007). Cells. Jones & Bartlett Learning. pp. 359. ISBN 978-0-7637-3905-8 2019年7月28日閲覧。
- ^ Kim, Sehyun; Dynlacht, Brian David (2013-08). “Assembling a primary cilium”. Current Opinion in Cell Biology 25 (4): 506–511. doi:10.1016/j.ceb.2013.04.011. ISSN 1879-0410. PMC: 3729615. PMID 23747070.
- ^ Klos Dehring, Deborah A.; Vladar, Eszter K.; Werner, Michael E.; Mitchell, Jennifer W.; Hwang, Peter; Mitchell, Brian J. (2013-10-14). “Deuterosome-mediated centriole biogenesis”. Developmental Cell 27 (1): 103–112. doi:10.1016/j.devcel.2013.08.021. ISSN 1878-1551. PMC: 3816757. PMID 24075808.
- ^ Pearson, Chad G.; Giddings, Thomas H.; Winey, Mark (2009-02). “Basal body components exhibit differential protein dynamics during nascent basal body assembly”. Molecular Biology of the Cell 20 (3): 904–914. doi:10.1091/mbc.e08-08-0835. ISSN 1939-4586. PMC: 2633379. PMID 19056680.
- ^ Ansley, Stephen J.; Badano, Jose L.; Blacque, Oliver E.; Hill, Josephine; Hoskins, Bethan E.; Leitch, Carmen C.; Kim, Jun Chul; Ross, Alison J. et al. (2003-10-09). “Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome”. Nature 425 (6958): 628–633. doi:10.1038/nature02030. ISSN 1476-4687. PMID 14520415.
- ^ Ferrante, Maria Immacolata; Zullo, Alessandro; Barra, Adriano; Bimonte, Sabrina; Messaddeq, Nadia; Studer, Michèle; Dollé, Pascal; Franco, Brunella (2006-01). “Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification”. Nature Genetics 38 (1): 112–117. doi:10.1038/ng1684. ISSN 1061-4036. PMID 16311594.
- ^ Romio, Leila; Fry, Andrew M.; Winyard, Paul J. D.; Malcolm, Sue; Woolf, Adrian S.; Feather, Sally A. (2004-10). “OFD1 is a centrosomal/basal body protein expressed during mesenchymal-epithelial transition in human nephrogenesis”. Journal of the American Society of Nephrology: JASN 15 (10): 2556–2568. doi:10.1097/01.ASN.0000140220.46477.5C. ISSN 1046-6673. PMID 15466260.
- ^ Arts, Heleen H.; Doherty, Dan; van Beersum, Sylvia E. C.; Parisi, Melissa A.; Letteboer, Stef J. F.; Gorden, Nicholas T.; Peters, Theo A.; Märker, Tina et al. (2007-07). “Mutations in the gene encoding the basal body protein RPGRIP1L, a nephrocystin-4 interactor, cause Joubert syndrome”. Nature Genetics 39 (7): 882–888. doi:10.1038/ng2069. ISSN 1061-4036. PMID 17558407.
- ^ Kobayashi, A.; Higashide, T.; Hamasaki, D.; Kubota, S.; Sakuma, H.; An, W.; Fujimaki, T.; McLaren, M. J. et al. (2000-10). “HRG4 (UNC119) mutation found in cone-rod dystrophy causes retinal degeneration in a transgenic model”. Investigative Ophthalmology & Visual Science 41 (11): 3268–3277. ISSN 0146-0404. PMID 11006213.
- ^ Shu, X.; Fry, A. M.; Tulloch, B.; Manson, F. D. C.; Crabb, J. W.; Khanna, H.; Faragher, A. J.; Lennon, A. et al. (2005-05-01). “RPGR ORF15 isoform co-localizes with RPGRIP1 at centrioles and basal bodies and interacts with nucleophosmin”. Human Molecular Genetics 14 (9): 1183–1197. doi:10.1093/hmg/ddi129. ISSN 0964-6906. PMID 15772089.
- ^ Kyttälä, Mira; Tallila, Jonna; Salonen, Riitta; Kopra, Outi; Kohlschmidt, Nicolai; Paavola-Sakki, Paulina; Peltonen, Leena; Kestilä, Marjo (2006-02). “MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome”. Nature Genetics 38 (2): 155–157. doi:10.1038/ng1714. ISSN 1061-4036. PMID 16415886.
- ^ Winkelbauer, Marlene E.; Schafer, Jenny C.; Haycraft, Courtney J.; Swoboda, Peter; Yoder, Bradley K. (2005-12-01). “The C. elegans homologs of nephrocystin-1 and nephrocystin-4 are cilia transition zone proteins involved in chemosensory perception”. Journal of Cell Science 118 (Pt 23): 5575–5587. doi:10.1242/jcs.02665. ISSN 0021-9533. PMID 16291722.
- ^ Shang, Yuhua; Tsao, Che-Chia; Gorovsky, Martin A. (2005-12-19). “Mutational analyses reveal a novel function of the nucleotide-binding domain of gamma-tubulin in the regulation of basal body biogenesis”. The Journal of Cell Biology 171 (6): 1035–1044. doi:10.1083/jcb.200508184. ISSN 0021-9525. PMC: 2171320. PMID 16344310.
- ^ Pack, Phillip E.,. Cliffsnotes AP biology. Cliffs Notes, Inc. (4th edition ed.). Boston. ISBN 978-1-118-12799-5. OCLC 811003769
[続きの解説]
「基底小体」の続きの解説一覧
- 1 基底小体とは
- 2 基底小体の概要
「basal body」の例文・使い方・用例・文例
- Basal bodyのページへのリンク
