CXCL10
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2024/05/10 16:06 UTC 版)
CXCL10（C-X-C motif chemokine ligand 10）またはIP-10（interferon gamma-induced protein 10）は、ヒトではCXCL10遺伝子にコードされる約8.7 kDaのタンパク質である[5][6]。CXCL10はCXCケモカインファミリーに属するサイトカインである。
- ^ a b c GRCh38: Ensembl release 89: ENSG00000169245 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034855 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
- ^ a b “Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins”. Nature 315 (6021): 672–6. (1985). Bibcode: 1985Natur.315..672L. doi:10.1038/315672a0. PMID 3925348.
- ^ “Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells”. Proceedings of the National Academy of Sciences of the United States of America 84 (9): 2868–71. (May 1987). Bibcode: 1987PNAS...84.2868L. doi:10.1073/pnas.84.9.2868. PMC 304761. PMID 2437586.
- ^ “CXCL10 C-X-C motif chemokine ligand 10 [Homo sapiens (Human)] - Gene - NCBI”. 2024年5月10日閲覧。
- ^ “Physical mapping of the CXC chemokine locus on human chromosome 4”. Cytogenetics and Cell Genetics 84 (1–2): 39–42. (1999). doi:10.1159/000015209. PMID 10343098.
- ^ “IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking”. Journal of Immunology 168 (7): 3195–204. (April 2002). doi:10.4049/jimmunol.168.7.3195. PMID 11907072.
- ^ “Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo”. The Journal of Experimental Medicine 182 (1): 155–62. (July 1995). doi:10.1084/jem.182.1.155. PMC 2192108. PMID 7540647.
- ^ “The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions”. Biochemistry 41 (33): 10418–25. (August 2002). doi:10.1021/bi026020q. PMID 12173928.
- ^ “Crystal structures of oligomeric forms of the IP-10/CXCL10 chemokine”. Structure 11 (5): 521–32. (May 2003). doi:10.1016/S0969-2126(03)00070-4. PMID 12737818.
- ^ “Left Ventricular Dysfunction and CXCR3 Ligands in Hypertension: From Animal Experiments to a Population-Based Pilot Study”. PLOS ONE 10 (10): e0141394. (2015). Bibcode: 2015PLoSO..1041394A. doi:10.1371/journal.pone.0141394. PMC 4624781. PMID 26506526.
- ^ “CXCL10 Is a Circulating Inflammatory Marker in Patients with Advanced Heart Failure: a Pilot Study”. Journal of Cardiovascular Translational Research 9 (4): 302–14. (August 2016). doi:10.1007/s12265-016-9703-3. PMID 27271043.
- ^ “Interferon (IFN)-gamma-inducible protein-10: association with histological results, viral kinetics, and outcome during treatment with pegylated IFN-alpha 2a and ribavirin for chronic hepatitis C virus infection”. The Journal of Infectious Diseases 194 (7): 895–903. (October 2006). doi:10.1086/507307. PMID 16960776.
- ^ “IP-10 predicts viral response and therapeutic outcome in difficult-to-treat patients with HCV genotype 1 infection”. Hepatology 44 (6): 1617–25. (December 2006). doi:10.1002/hep.21407. PMID 17133471.
- ^ “Systemic and intrahepatic interferon-gamma-inducible protein 10 kDa predicts the first-phase decline in hepatitis C virus RNA and overall viral response to therapy in chronic hepatitis C”. Hepatology 51 (5): 1523–30. (May 2010). doi:10.1002/hep.23509. PMID 20186843.
- ^ “IP-10 predicts the first phase decline of HCV RNA and overall viral response to therapy in patients co-infected with chronic hepatitis C virus infection and HIV”. Scandinavian Journal of Infectious Diseases 42 (11–12): 896–901. (December 2010). doi:10.3109/00365548.2010.498019. PMID 20608766.
- ^ “Pathogen Evasion of Chemokine Response Through Suppression of CXCL10”. Frontiers in Cellular and Infection Microbiology 9: 280. (2019). doi:10.3389/fcimb.2019.00280. PMC 6693555. PMID 31440475.
[続きの解説]
「CXCL10」の続きの解説一覧
- 1 CXCL10とは
- 2 CXCL10の概要
- 3 遺伝子
- 4 関連文献
- 5 外部リンク
- CXCL10のページへのリンク
