エキソソーム複合体 参照

ウィキペディア
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エキソソーム複合体

出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/05/28 09:39 UTC 版)

エキソソーム複合体（エキソソームふくごうたい、英: Exosome Complex、PM/Scl複合体、単にエキソソーム、エクソソームとも）は、真核生物、古細菌の核に存在し、様々なRNAを分解する多タンパク質複合体である。細菌ではデグラドソーム（英語版）と呼ばれる複合体が似た役割を果たす。


出典
  1. ^ a b Mitchell, P; Petfalski, E; Shevchenko, A; Mann, M; Tollervey, D (1997), “The Exosome: A Conserved Eukaryotic RNA Processing Complex Containing Multiple 3′→5′ Exoribonucleases”, Cell 91 (4): 457–466, doi:10.1016/S0092-8674(00)80432-8, PMID 9390555 
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  23. ^ Wang, L; Lewis, MS; Johnson, AW (2005), “Domain interactions within the Ski2/3/8 complex and between the Ski complex and Ski7p”, RNA 11 (8): 1291–302, doi:10.1261/rna.2060405, PMC 1370812, PMID 16043509, http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1370812 
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  25. ^ Liu, Q; Greimann, JC; Lima, CD (2007), “Erratum: Reconstitution, activities, and structure of the eukaryotic RNA exosome”, Cell 131 (1): 188–189, doi:10.1016/j.cell.2007.09.019 
  26. ^ a b Dziembowski, A; Lorentzen, E; Conti, E; Séraphin, B (2007), “A single subunit, Dis3, is in essence responsible for yeast exosome core activity”, Nature Structural & Molecular Biology 14 (1): 15–22, doi:10.1038/nsmb1184, PMID 17173052 
  27. ^ Liu, Q; Greimann, JC; Lima, CD (2006), “Reconstitution, activities, and structure of the eukaryotic RNA exosome”, Cell 127 (6): 1223–37, doi:10.1016/j.cell.2006.10.037, PMID 17174896 
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  29. ^ LeJeune, F; Li, X; Maquat, LE (2003), “Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities”, Molecular Cell 12 (3): 675–87, doi:10.1016/S1097-2765(03)00349-6, PMID 14527413 
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  31. ^ Lin, WJ; Duffy, A; Chen, CY (2007), “Localization of AU-rich element-containing mRNA in cytoplasmic granules containing exosome subunits”, Journal of Biological Chemistry 282 (27): 19958–68, doi:10.1074/jbc.M702281200, PMID 17470429 
  32. ^ a b Allmang, C; Kufel, J; Chanfreau, G; Mitchell, P; Petfalski, E; Tollervey, D (1999), “Functions of the exosome in rRNA, snoRNA and snRNA synthesis”, EMBO Journal 18 (19): 5399–410, doi:10.1093/emboj/18.19.5399, PMC 1171609, PMID 10508172, http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1171609 
  33. ^ Schilders, G; Raijmakers, R; Raats, JM; Pruijn, GJ (2005), “MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturation”, Nucleic Acids Research 33 (21): 6795–804, doi:10.1093/nar/gki982, PMC 1310903, PMID 16396833, http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1310903 
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エキソソーム複合体のお隣キーワード

エキセントリック (曲)

エキセントリック (機械要素)

エキセントリック・プラネット

エキセントリック少年ボウイオールスターズ

エキソサイトーシス

エキソソーム

エキソソーム複合体

エキソデオキシリボヌクレアーゼI

エキソデオキシリボヌクレアーゼIII

エキソドス (アルバム)

エキソニモ

エキソヌクレアーゼ

エキソヌクレアーゼVII

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