ヒスタミンH2受容体
「生物学用語辞典」の他の用語
| 酵素タンパク質モチーフなど： | ヌクレアーゼ バソプレッシン受容体 パーレカン ヒスタミンH2受容体 ヒスタミン受容体 ヒト絨毛性性腺刺激ホルモン ビタミンA核内受容体 |
ヒスタミン受容体
(ヒスタミンH2-受容体 から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/06/06 21:17 UTC 版)
ヒスタミン受容体（ヒスタミンじゅようたい、Histamine Receptor）とは生理活性物質であるヒスタミンの受け皿として働くタンパク質である。ヒスタミンは肥満細胞などで産生される物質であり、組織が抗原にさらされた時や炎症が生じた場合に細胞外に放出されて機能する[1][2]。
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- ^ ROWLEY DA and BENDITT EP.(1956)"5-Hydroxytryptamine and histamine as mediators of the vascular injury produced by agents which damage mast cells in rats."J Exp Med 103,399-412. PMID 13306850
- ^ Lee JY, Buckner SA, Brune ME, Warner RB, Winn M, De B, Zydowsky TM, Opgenorth TJ, Kerkman DJ and Debernardis JF.(1966)"Characterization of antihypertensive activity of ABBOTT-81988, a nonpeptide angiotensin II antagonist in the renal hypertensive rat."J Pharmacol Exp Ther. 27,427-39. PMID 8301584
- ^ Lim HD, van Rijn RM, Ling P, Bakker RA, Thurmond RL and Leurs R.(2005)"Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist."J Pharmacol Exp Ther 314,1310-21. PMID 15947036
- ^ “医療用医薬品 : ニザチジン”. 2022年6月7日閲覧。
- ^ “KEGG DRUG:ピトリサント塩酸塩”. 2022年6月7日閲覧。
- ^ “アキュリスファーマがヒスタミンH3受容体拮抗薬/逆作動薬pitolisantの国内第1相臨床試験開始(2022年2月5日)”. 2022年6月7日閲覧。
- ^ Tatsuro Shimamura, Mitsunori Shiroishi, Simone Weyand, Hirokazu Tsujimoto, Graeme Winter, Vsevolod Katritch, Ruben Abagyan, Vadim Cherezov, Wei Liu, Gye Won Han, Takuya Kobayashi, Raymond C. Stevens & So Iwata (July 2011). “Structure of the human histamine H1 receptor complex with doxepin”. Nature 475 (7354): 65–70. doi:10.1038/nature10236. PMID 21697825.
- ^ Del Valle J and Gantz I.(1997)"Novel insights into histamine H2 receptor biology."Am J Physiol 273,g987-96. PMID 9374694
- ^ Tari A, Yamamoto G, Sumii K, Sumii M, Takehara Y, Haruma K, Kajiyama G, Wu V, Sachs G and Walsh JH.(1993)"Role of histamine2 receptor in increased expression of rat gastric H(+)-K(+)-ATPase alpha-subunit induced by omeprazole."Am J Physiol 265,g752-8. PMID 8238359
- ^ Sansoni P, Silverman ED, Khan MM, Melmon KL and Engleman EG.(1985)"Immunoregulatory T cells in man. Histamine-induced suppressor T cells are derived from a Leu 2+ (T8+) subpopulation distinct from that which gives rise to cytotoxic T cells."J Clin Invest 75,650-6 PMID 3156150
- ^ Jutel M, Watanabe T, Klunker S, Akdis M, Thomet OA, Malolepszy J, Zak-Nejmark T, Koga R, Kobayashi T, Blaser K and Akdis CA.(2001)"Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors."Nature 413,420-5. PMID 11574888
- ^ Lichtenstein LM and Gillespie E.(1975)"The effects of the H1 and H2 antihistamines on "allergic" histamine release and its inhibition by histamine."J Pharmacol Exp Ther 192,441-50. PMID 46921
- ^ Arrang JM, Garbarg M and Schwartz JC.(1983)"Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor."Nature 302,832-7. PMID 6188956
- ^ Bertaccini G, Coruzzi G, Adami M, Pozzoli C and Gambarelli E.(1991)"Histamine H3 receptors: an overview."Ital J Gastroenterol 23,378-85. PMID 1660330
- ^ Lovenberg TW, Pyati J, Chang H, Wilson SJ and Erlander MG.(2000)"Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles."J Pharmacol Exp Ther 293,771-8. PMID 10869375
- ^ Sander K, Kottke T and Stark H.(2008)"Histamine H3 receptor antagonists go to clinics."Biol Pharm Bull 31,2163-81. PMID 19043195
- ^ Hofstra CL, Desai PJ, Thurmond RL and Fung-Leung WP.(2003)"Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells."J Pharmacol Exp Ther 305,1212-21 PMID 12626656
- ^ Ling P, Ngo K, Nguyen S, Thurmond RL, Edwards JP, Karlsson L and Fung-Leung WP.(2004)"Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation."Br J Pharmacol 142,161-71. PMID 15131002
- ^ Takeshita K, Bacon KB and Gantner F.(2004)"Critical role of L-selectin and histamine H4 receptor in zymosan-induced neutrophil recruitment from the bone marrow: comparison with carrageenan."J Pharmacol Exp Ther 310,272-80. PMID 14996947
- ^ Gutzmer R, Diestel C, Mommert S, Köther B, Stark H, Wittmann M and Werfel T.(2005)"Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells."J Immunol 174,5224-32. PMID 15843518
- ^ Nakayama T, Kato Y, Hieshima K, Nagakubo D, Kunori Y, Fujisawa T and Yoshie O.(2004)"Liver-expressed chemokine/CC chemokine ligand 16 attracts eosinophils by interacting with histamine H4 receptor."J Immunol 173,2078-83. PMID 15265943
[続きの解説]
「ヒスタミン受容体」の続きの解説一覧
- 1 ヒスタミン受容体とは
- 2 ヒスタミン受容体の概要
- 3 関連項目
ヒスタミンH2-受容体と同じ種類の言葉
- ヒスタミンH2-受容体のページへのリンク
