シクロオキシゲナーゼ-2
シクロオキシゲナーゼ2
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2021/11/06 20:32 UTC 版)
シクロオキシゲナーゼ2（英: cyclooxygenase-2、略称: COX-2）またはプロスタグランジンエンドペルオキシドシンターゼ2（英: prostaglandin-endoperoxide synthase 2、略称: PTGS2）は、ヒトではPTGS2遺伝子にコードされる酵素である[5]。COX-2はヒトに2種類存在するシクロオキシゲナーゼのうちの1つである。COX-2はアラキドン酸からプロスタグランジンH2への変換に関与しており、炎症時に発現する。プロスタグランジンH2はプロスタサイクリンの重要な前駆体である。
- ^ a b c GRCh38: Ensembl release 89: ENSG00000073756 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032487 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
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