シクロオキシゲナーゼ2
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2021/11/06 20:32 UTC 版)
外部リンク
- Nextbio
- NSAIDs and Cardiovascular Risk Explained, According to Studies from the Perelman School of Medicine
- ^ a b c GRCh38: Ensembl release 89: ENSG00000073756 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032487 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
- ^ “Human cyclooxygenase-2 cDNA”. Proc. Natl. Acad. Sci. U.S.A. 89 (16): 7384–8. (August 1992). Bibcode: 1992PNAS...89.7384H. doi:10.1073/pnas.89.16.7384. PMC 49714. PMID 1380156.
- ^ “Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology”. Crit Rev Neurobiol 13 (1): 45–82. (1999). doi:10.1615/critrevneurobiol.v13.i1.30. PMID 10223523.
- ^ “Identification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2”. J. Lipid Res. 51 (3): 575–85. (2010). doi:10.1194/jlr.M001719. PMC 2817587. PMID 19752399.
- ^ “Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution”. Prostaglandins Leukot. Essent. Fatty Acids 73 (3–4): 141–62. (2005). doi:10.1016/j.plefa.2005.05.002. PMID 16005201.
- ^ Wang Q1, He Y, Shen Y, Zhang Q, Chen D, Zuo C, Qin J, Wang H, Wang J, Yu Y. (2014). “Vitamin D inhibits COX-2 expression and inflammatory response by targeting thioesterase superfamily member 4”. J Biol Chem 289 (17): 11681–11694. doi:10.1074/jbc.M113.517581. PMC 4002078. PMID 24619416.
- ^ Kassi E1, Adamopoulos C, Basdra EK, Papavassiliou AG. (2013). “Role of Vitamin D in Atherosclerosis”. Circulation 128 (23): 2517–2531. doi:10.1161/CIRCULATIONAHA.113.002654. PMID 24297817.
- ^ “Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2”. J. Biol. Chem. 271 (52): 33157–60. (December 1996). doi:10.1074/jbc.271.52.33157. PMID 8969167.
- ^ “A mechanistic study of self-inactivation of the peroxidase activity in prostaglandin H synthase-1”. J. Biol. Chem. 274 (14): 9231–7. (April 1999). doi:10.1074/jbc.274.14.9231. PMID 10092596.
- ^ “The kinetic factors that determine the affinity and selectivity for slow binding inhibition of human prostaglandin H synthase 1 and 2 by indomethacin and flurbiprofen”. J. Biol. Chem. 271 (7): 3548–54. (February 1996). doi:10.1074/jbc.271.7.3548. PMID 8631960.
- ^ “Mechanisms for the autoxidation of polyunsaturated lipids”. Accounts of Chemical Research 19 (9): 262–8. (1986). doi:10.1021/ar00129a001.
- ^ “A carbon-centered free radical intermediate in the prostaglandin synthetase oxidation of arachidonic acid. Spin trapping and oxygen uptake studies”. J. Biol. Chem. 255 (11): 5019–22. (June 1980). doi:10.1016/S0021-9258(19)70741-8. PMID 6246094.
- ^ “Identification of novel arachidonic acid metabolites formed by prostaglandin H synthase”. Eur. J. Biochem. 169 (1): 113–23. (November 1987). doi:10.1111/j.1432-1033.1987.tb13587.x. PMID 3119336.
- ^ “Analysis of hydroperoxide-induced tyrosyl radicals and lipoxygenase activity in aspirin-treated human prostaglandin H synthase-2”. Biochemistry 36 (7): 1836–45. (February 1997). doi:10.1021/bi962476u. PMID 9048568.
- ^ “Enzymatic conversions of 10,10-difluoroarachidonic acid with PGH synthase and soybean lipoxygenase”. Journal of the American Chemical Society 109 (12): 3692–3698. (June 1987). doi:10.1021/ja00246a028.
- ^ “Carbocations in the synthesis of prostaglandins by the cyclooxygenase of PGH synthase? A radical departure!”. Protein Sci. 8 (5): 1087–98. (May 1999). doi:10.1110/ps.8.5.1087. PMC 2144324. PMID 10338019.
- ^ “On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha”. J. Biol. Chem. 242 (22): 5336–43. (November 1967). doi:10.1016/S0021-9258(18)99433-0. PMID 6070851.
- ^ a b “Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer”. J. Biol. Chem. 286 (21): 19035–46. (May 2011). doi:10.1074/jbc.M111.231969. PMC 3099718. PMID 21467029.
- ^ “The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1”. Nature 367 (6460): 243–9. (January 1994). Bibcode: 1994Natur.367..243P. doi:10.1038/367243a0. PMID 8121489.
- ^ a b “Cyclooxygenase enzymes: catalysis and inhibition”. Curr. Opin. Struct. Biol. 11 (6): 752–60. (December 2001). doi:10.1016/S0959-440X(01)00277-9. PMID 11751058.
- ^ a b “Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function”. Proc. Natl. Acad. Sci. U.S.A. 106 (18): 7548–52. (May 2009). Bibcode: 2009PNAS..106.7548W. doi:10.1073/pnas.0805806106. PMC 2670242. PMID 19376970.
- ^ Ruan, C. H.; So, S. P.; Ruan, K. H. (2011). “Inducible COX-2 dominates over COX-1 in prostacyclin biosynthesis: Mechanisms of COX-2 inhibitor risk to heart disease”. Life Sciences 88 (1–2): 24–30. doi:10.1016/j.lfs.2010.10.017. PMC 3046773. PMID 21035466.
- ^ “Cyclooxygenase-2, p53 and glucose transporter-1 as predictors of malignancy in the development of gallbladder carcinomas”. Bosn J Basic Med Sci 10 (3): 192–6. (August 2010). doi:10.17305/bjbms.2010.2684. PMC 5504494. PMID 20846124.
- ^ “Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward”. Clin. Cancer Res. 16 (5): 1384–90. (March 2010). doi:10.1158/1078-0432.CCR-09-0788. PMC 4307592. PMID 20179228.
- ^ KASE, SATORU; SAITO, WATARU; OHNO, SHIGEAKI; ISHIDA, SUSUMU (2010). “Cyclo-Oxygenase-2 Expression in Human Idiopathic Epiretinal Membrane”. Retina 30 (5): 719–723. doi:10.1097/iae.0b013e3181c59698. PMID 19996819.
- ^ Tikhonovich, Marina V.; Erdiakov, Aleksei K.; Gavrilova, Svetlana A. (2017-06-21). “Nonsteroid anti-inflammatory therapy suppresses the development of proliferative vitreoretinopathy more effectively than a steroid one” (英語). International Ophthalmology 38 (4): 1365–1378. doi:10.1007/s10792-017-0594-3. ISSN 0165-5701. PMID 28639085.
- ^ Phillips, Robert J.; Fortier, Michel A.; López Bernal, Andrés (2014-07-22). “Prostaglandin pathway gene expression in human placenta, amnion and choriodecidua is differentially affected by preterm and term labour and by uterine inflammation”. BMC pregnancy and childbirth 14: 241. doi:10.1186/1471-2393-14-241. ISSN 1471-2393. PMC 4223419. PMID 25048443.
- ^ “A new cyclo-oxygenase-2 gene variant in the Han Chinese population is associated with an increased risk of gastric carcinoma”. Mol Diagn Ther 14 (6): 351–5. (December 2010). doi:10.1007/bf03256392. PMID 21275453.
- ^ “Colocalization and interaction of cyclooxygenase-2 with caveolin-1 in human fibroblasts”. J. Biol. Chem. 276 (37): 34975–82. (September 2001). doi:10.1074/jbc.M105946200. PMID 11432874.
- ^ “Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing”. Proc. Natl. Acad. Sci. U.S.A. 88 (7): 2692–6. (April 1991). Bibcode: 1991PNAS...88.2692X. doi:10.1073/pnas.88.7.2692. PMC 51304. PMID 1849272.
[前の解説]
「シクロオキシゲナーゼ2」の続きの解説一覧
シクロオキシゲナーゼ2と同じ種類の言葉
| シクロに関連する言葉 | シクロ シクロオキシゲナーゼ-2 シクロヘキシミド |
- シクロオキシゲナーゼ2のページへのリンク
