RAF1とは? わかりやすく解説

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RAF1

出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2023/03/28 02:46 UTC 版)

RAF1はヒトではRAF1遺伝子にコードされる酵素である[4][5][6]c-Raf(proto-oncogene c-RAF)という名称が用いられることもあり、他にもRAF proto-oncogene serine/threonine-protein kinase、Raf-1などとも呼ばれる。c-RafはMAPK/ERK経路英語版(ERK1/2経路)を構成し、Rasサブファミリーの下流のMAPキナーゼキナーゼキナーゼ(MAP3K)として機能する[7]。c-Rafはセリン/スレオニンキナーゼRafキナーゼファミリーのメンバーであり、TKL(Tyrosine-kinase-like)グループに属する。


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