Kleisin
出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2020/03/18 00:36 UTC 版)
kleisin(くれいしん)は、SMCタンパク質と結合する一群のタンパク質の総称[1]。SMCタンパク質ともに巨大なタンパク質複合体のサブユニットとして働き、染色体の高次構造と機能の制御に関わる。
- ^ Schleiffer A, Kaitna S, Maurer-Stroh S, Glotzer M, Nasmyth K, Eisenhaber F. (2003). “Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners.”. Mol. Cell 11 (3): 571-575. PMID 12667442.
- ^ Haering CH, Schoffnegger D, Nishino T, Helmhart W, Nasmyth K, Löwe J. (2004). “Structure and stability of cohesin's Smc1-kleisin interaction.”. Mol. Cell 15 (6): 951-964. PMID 15383284.
- ^ Woo JS, Lim JH, Shin HC, Suh MK, Ku B, Lee KH, Joo K, Robinson H, Lee J, Park SY, Ha NC, Oh BH. (2008). “Structural studies of a bacterial condensin complex reveal ATP-dependent disruption of intersubunit interactions.”. Cell 136 (1): 85-96. PMID 19135891.
- ^ a b Hassler M, Shaltiel IA, Kschonsak M, Simon B, Merkel F, Thärichen L, Bailey HJ, Macošek J, Bravo S, Metz J, Hennig J, Haering CH (2019). “Structural basis of an asymmetric condensin ATPase cycle”. Mol Cell 74 (6): 1175-1188.e24. PMID 31226277.
- ^ Bürmann F, Shin HC, Basquin J, Soh YM, Giménez-Oya V, Kim YG, Oh BH, Gruber S. (2013). “An asymmetric SMC-kleisin bridge in prokaryotic condensin”. Nat. Struct. Mol. Biol. 20 (3): 371-379. PMID 23353789.
- ^ Gligoris TG, Scheinost JC, Bürmann F, Petela N, Chan KL, Uluocak P, Beckouët F, Gruber S, Nasmyth K, Löwe J. (2014). “Closing the cohesin ring: structure and function of its Smc3-kleisin interface”. Science 346 (6212): 963-967. PMID 25414305.
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