ジョージ・チャーチ (遺伝学者)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/11/18 03:21 UTC 版)
ジョージ・マクドナルド・チャーチ（George McDonald Church、1954年8月28日 - ）は、アメリカ合衆国の遺伝学者、分子工学者、化学者。 ハーバード大学医学部ロバート・ウィンスロップ遺伝学教授、マサチューセッツ工科大学教授、原子科学者会報理事。ヴィース研究所（Wyss Institute for Biologically Inspired Engineering）共同創立者[2]。
- ^ a b “Church, George”. Biography Reference Bank. The H. W. Wilson Company (2010年). 2011年12月10日閲覧。[リンク切れ]
- ^ Nair, P. (2012). “Profile of George M. Church”. Proceedings of the National Academy of Sciences 109 (30): 11893–11895. Bibcode: 2012PNAS..10911893N. doi:10.1073/pnas.1204148109. PMC 3409755. PMID 22474375.
- ^ Church, G.; Gilbert, W. (1984). “Genomic sequencing”. Proceedings of the National Academy of Sciences of the United States of America 81 (7): 1991–1995. Bibcode: 1984PNAS...81.1991C. doi:10.1073/pnas.81.7.1991. PMC 345422. PMID 6326095.
- ^ Segrè, D.; Vitkup, D.; Church, G. M. (2002). “Analysis of optimality in natural and perturbed metabolic networks”. Proceedings of the National Academy of Sciences of the United States of America 99 (23): 15112–15117. Bibcode: 2002PNAS...9915112S. doi:10.1073/pnas.232349399. PMC 137552. PMID 12415116.
- ^ Chae, H. Z.; Robison, K; Poole, L. B.; Church, G; Storz, G; Rhee, S. G. (1994). “Cloning and sequencing of thiol-specific antioxidant from mammalian brain: Alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes”. Proceedings of the National Academy of Sciences of the United States of America 91 (15): 7017–21. Bibcode: 1994PNAS...91.7017C. doi:10.1073/pnas.91.15.7017. PMC 44329. PMID 8041738.
- ^ Kim, J.; Krichevsky, A.; Grad, Y.; Hayes, G.; Kosik, K.; Church, G.; Ruvkun, G. (2004). “Identification of many microRNAs that copurify with polyribosomes in mammalian neurons”. Proceedings of the National Academy of Sciences of the United States of America 101 (1): 360–365. Bibcode: 2003PNAS..101..360K. doi:10.1073/pnas.2333854100. PMC 314190. PMID 14691248.
- ^ Tavazoie, S; Hughes, J. D.; Campbell, M. J.; Cho, R. J.; Church, G. M. (1999). “Systematic determination of genetic network architecture”. Nature Genetics 22 (3): 281–5. doi:10.1038/10343. PMID 10391217.
- ^ Pilpel, Y; Sudarsanam, P; Church, G. M. (2001). “Identifying regulatory networks by combinatorial analysis of promoter elements”. Nature Genetics 29 (2): 153–9. doi:10.1038/ng724. PMID 11547334.
- ^ Ge, H; Liu, Z; Church, G. M.; Vidal, M (2001). “Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae”. Nature Genetics 29 (4): 482–6. doi:10.1038/ng776. PMID 11694880.
- ^ Shendure, J; Mitra, R. D.; Varma, C; Church, G. M. (2004). “Advanced sequencing technologies: Methods and goals”. Nature Reviews Genetics 5 (5): 335–44. doi:10.1038/nrg1325. PMID 15143316.
- ^ Cheng, Y; Church, G. M. (2000). “Biclustering of expression data”. Proceedings. International Conference on Intelligent Systems for Molecular Biology 8: 93–103. PMID 10977070.
- ^ Tompa, M; Li, N; Bailey, T. L.; Church, G. M.; De Moor, B; Eskin, E; Favorov, A. V.; Frith, M. C. et al. (2005). “Assessing computational tools for the discovery of transcription factor binding sites”. Nature Biotechnology 23 (1): 137–44. doi:10.1038/nbt1053. PMID 15637633.
- ^ Roth, F. P.; Hughes, J. D.; Estep, P. W.; Church, G. M. (1998). “Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation”. Nature Biotechnology 16 (10): 939–45. doi:10.1038/nbt1098-939. PMID 9788350.
- ^ Ball, M. P.; Li, J. B.; Gao, Y; Lee, J. H.; Leproust, E. M.; Park, I. H.; Xie, B; Daley, G. Q. et al. (2009). “Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells”. Nature Biotechnology 27 (4): 361–8. doi:10.1038/nbt.1533. PMC 3566772. PMID 19329998.
- ^ Selinger, D. W.; Cheung, K. J.; Mei, R; Johansson, E. M.; Richmond, C. S.; Blattner, F. R.; Lockhart, D. J.; Church, G. M. (2000). “RNA expression analysis using a 30 base pair resolution Escherichia coli genome array”. Nature Biotechnology 18 (12): 1262–8. doi:10.1038/82367. PMID 11101804.
- ^ Mali, P.; Yang, L.; Esvelt, K. M.; Aach, J.; Guell, M.; Dicarlo, J. E.; Norville, J. E.; Church, G. M. (2013). “RNA-Guided Human Genome Engineering via Cas9”. Science 339 (6121): 823–826. Bibcode: 2013Sci...339..823M. doi:10.1126/science.1232033. PMC 3712628. PMID 23287722.
- ^ Shendure, J.; Porreca, J.; Reppas, B.; Lin, X.; McCutcheon, P.; Rosenbaum, M.; Wang, D.; Zhang, K. et al. (September 2005). “Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome”. Science 309 (5741): 1728–1732. Bibcode: 2005Sci...309.1728S. doi:10.1126/science.1117389. ISSN 0036-8075. PMID 16081699.
- ^ Ephrussi, A; Church, G. M.; Tonegawa, S; Gilbert, W (1985). “B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo”. Science 227 (4683): 134–40. Bibcode: 1985Sci...227..134E. doi:10.1126/science.3917574. PMID 3917574.
- ^ Drmanac, R; Sparks, A. B.; Callow, M. J.; Halpern, A. L.; Burns, N. L.; Kermani, B. G.; Carnevali, P; Nazarenko, I et al. (2010). “Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays”. Science 327 (5961): 78–81. Bibcode: 2010Sci...327...78D. doi:10.1126/science.1181498. PMID 19892942.
- ^ Sommer, M. O. A.; Dantas, G.; Church, G. M. (2009). “Functional Characterization of the Antibiotic Resistance Reservoir in the Human Microflora”. Science 325 (5944): 1128–1131. Bibcode: 2009Sci...325.1128S. doi:10.1126/science.1176950. PMC 4720503. PMID 19713526.
- ^ Friedland, A. E.; Lu, T. K.; Wang, X; Shi, D; Church, G; Collins, J. J. (2009). “Synthetic gene networks that count”. Science 324 (5931): 1199–202. Bibcode: 2009Sci...324.1199F. doi:10.1126/science.1172005. PMC 2690711. PMID 19478183.
- ^ Hughes, J. D.; Estep, P. W.; Tavazoie, S; Church, G. M. (2000). “Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae”. Journal of Molecular Biology 296 (5): 1205–14. doi:10.1006/jmbi.2000.3519. PMID 10698627.
- ^ Sussman, J. L.; Holbrook, S. R.; Warrant, R. W.; Church, G. M.; Kim, S. H. (1978). “Crystal structure of yeast phenylalanine transfer RNA. I. Crystallographic refinement”. Journal of Molecular Biology 123 (4): 607–30. doi:10.1016/0022-2836(78)90209-7. PMID 357742.
- ^ Robison, K; McGuire, A. M.; Church, G. M. (1998). “A comprehensive library of DNA-binding site matrices for 55 proteins applied to the complete Escherichia coli K-12 genome”. Journal of Molecular Biology 284 (2): 241–54. doi:10.1006/jmbi.1998.2160. PMID 9813115.
- ^ Chen, T; He, H. L.; Church, G. M. (1999). “Modeling gene expression with differential equations”. Pacific Symposium on Biocomputing: 29–40. PMID 10380183.
- ^ Link, A. J.; Phillips, D.; Church, G. M. (1997). “Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: Application to open reading frame characterization”. Journal of Bacteriology 179 (20): 6228–6237. doi:10.1128/jb.179.20.6228-6237.1997. PMC 179534. PMID 9335267.
- ^ Wang, H. H.; Isaacs, F. J.; Carr, P. A.; Sun, Z. Z.; Xu, G; Forest, C. R.; Church, G. M. (2009). “Programming cells by multiplex genome engineering and accelerated evolution”. Nature 460 (7257): 894–8. Bibcode: 2009Natur.460..894W. doi:10.1038/nature08187. PMC 4590770. PMID 19633652.
- ^ Porreca, G. J.; Zhang, K.; Li, J. B.; Xie, B.; Austin, D.; Vassallo, S. L.; Leproust, E. M.; Peck, B. J. et al. (2007). “Multiplex amplification of large sets of human exons”. Nature Methods 4 (11): 931–6. doi:10.1038/nmeth1110. PMID 17934468.
- ^ Choe, S. E.; Boutros, M; Michelson, A. M.; Church, G. M.; Halfon, M. S. (2005). “Preferred analysis methods for Affymetrix Gene Chips revealed by a wholly defined control dataset”. Genome Biology 6 (2): R16. doi:10.1186/gb-2005-6-2-r16. PMC 551536. PMID 15693945.
- ^ Aach, J; Church, G. M. (2001). “Aligning gene expression time series with time warping algorithms”. Bioinformatics 17 (6): 495–508. doi:10.1093/bioinformatics/17.6.495. PMID 11395426.
- ^ Teichmann, S. A.; Chothia, C; Church, G. M.; Park, J (2000). “Fast assignment of protein structures to sequences using the intermediate sequence library PDB-ISL”. Bioinformatics 16 (2): 117–24. doi:10.1093/bioinformatics/16.2.117. PMID 10842732.
- ^ Kettler, G. C.; Martiny, A. C.; Huang, K; Zucker, J; Coleman, M. L.; Rodrigue, S; Chen, F; Lapidus, A et al. (2007). “Patterns and implications of gene gain and loss in the evolution of Prochlorococcus”. PLOS Genetics 3 (12): e231. doi:10.1371/journal.pgen.0030231. PMC 2151091. PMID 18159947.
- ^ Bulyk, M. L.; Johnson, P. L.; Church, G. M. (2002). “Nucleotides of transcription factor binding sites exert interdependent effects on the binding affinities of transcription factors”. Nucleic Acids Research 30 (5): 1255–61. doi:10.1093/nar/30.5.1255. PMC 101241. PMID 11861919.
[続きの解説]
「ジョージ・チャーチ (遺伝学者)」の続きの解説一覧
- 1 ジョージ・チャーチ (遺伝学者)とは
- 2 ジョージ・チャーチ (遺伝学者)の概要
- 3 外部リンク
- ジョージ・チャーチ (遺伝学者)のページへのリンク
