成長ホルモン受容体
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成長ホルモン受容体
(Growth Hormone Receptor から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/01/01 07:26 UTC 版)
成長ホルモン受容体（せいちょうホルモンじゅようたい、英: growth hormone receptor、略称: GHR）は、ヒトではGHR遺伝子によってコードされるタンパク質である[5]。GHRのオルソログはほとんどの哺乳類で同定されている[6]。
- ^ a b c GRCh38: Ensembl release 89: ENSG00000112964 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000055737 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
- ^ a b “Entrez Gene: GHR growth hormone receptor”. 2021年9月4日閲覧。
- ^ “ENSG00000112964_GHR”. orthomam.mbb.cnrs.fr. 2021年9月4日閲覧。
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- ^ “The growth hormone receptor: mechanism of activation and clinical implications”. Nature Reviews. Endocrinology 6 (9): 515–25. (September 2010). doi:10.1038/nrendo.2010.123. PMID 20664532.
- ^ “Differential regulation of membrane associated-growth hormone binding protein (MA-GHBP) and growth hormone receptor (GHR) expression by growth hormone (GH) in mouse liver”. Growth Hormone & IGF Research 17 (2): 104–12. (April 2007). doi:10.1016/j.ghir.2006.12.002. PMID 17321774.
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- ^ List, Edward O.; Sackmann-Sala, Lucila; Berryman, Darlene E.; Funk, Kevin; Kelder, Bruce; Gosney, Elahu S.; Okada, Shigeru; Ding, Juan et al. (2011-06). “Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse”. Endocrine Reviews 32 (3): 356–386. doi:10.1210/er.2010-0009. ISSN 1945-7189. PMC 3365798. PMID 21123740.
- ^ a b “Mitogenomic Phylogeny, Diversification, and Biogeography of South American Spiny Rats”. Molecular Biology and Evolution 34 (3): 613–633. (March 2017). doi:10.1093/molbev/msw261. PMID 28025278.
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- ^ “Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B”. Molecular Endocrinology 14 (9): 1338–50. (September 2000). doi:10.1210/me.14.9.1338. PMID 10976913.
- ^ “Grb10 identified as a potential regulator of growth hormone (GH) signaling by cloning of GH receptor target proteins”. The Journal of Biological Chemistry 273 (26): 15906–12. (June 1998). doi:10.1074/jbc.273.26.15906. PMID 9632636.
- ^ “Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor”. The Journal of Biological Chemistry 270 (24): 14776–85. (June 1995). doi:10.1074/jbc.270.24.14776. PMID 7540178.
- ^ “Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase”. The Journal of Biological Chemistry 269 (34): 21709–17. (August 1994). doi:10.1016/S0021-9258(17)31863-X. PMID 8063815.
- ^ “The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver”. Growth Hormone & IGF Research 9 (3): 212–8. (June 1999). doi:10.1054/ghir.1999.0111. PMID 10502458.
- ^ a b “SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms”. The Journal of Biological Chemistry 274 (50): 35553–61. (December 1999). doi:10.1074/jbc.274.50.35553. PMID 10585430.
- ^ “OrthoMaM phylogenetic marker: GHR coding sequence”. 2015年9月24日時点のオリジナルよりアーカイブ。2009年11月18日閲覧。
- ^ “Molecular phylogeny and divergence time estimates for major rodent groups: evidence from multiple genes”. Molecular Biology and Evolution 18 (5): 777–91. (May 2001). doi:10.1093/oxfordjournals.molbev.a003860. PMID 11319262.
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- ^ “Molecular phylogeny of the Arctoidea (Carnivora): effect of missing data on supertree and supermatrix analyses of multiple gene data sets”. Molecular Phylogenetics and Evolution 41 (1): 165–81. (October 2006). doi:10.1016/j.ympev.2006.05.025. PMID 16814570.
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- ^ “Scientific Discussion of Somavert”. European Medicines Agency (2004年). 2021年9月4日閲覧。
[続きの解説]
「成長ホルモン受容体」の続きの解説一覧
- 1 成長ホルモン受容体とは
- 2 成長ホルモン受容体の概要
- 3 構造
- 4 進化
- Growth Hormone Receptorのページへのリンク
