DNA結合タンパク質
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/01/06 09:02 UTC 版)
DNA結合タンパク質とはDNA結合ドメインを有するタンパク質である。従って、一本鎖または二本鎖DNAに対して特異的または非特異的な親和性を有する[3] [4] [5]。配列特異的DNA結合タンパク質は一般に、塩基対を識別する官能基が比較的多いB-DNAの主溝と相互作用する。一方で、ネトロプシン [6] 、ジスタマイシン、ヘキスト33258 、 ペンタミジン 、 DAPIなどのDNA副溝結合リガンドもいくつか知られている[7]。
- ^ Created from PDB 1LMB
- ^ Created from PDB 1RVA
- ^ Travers, A. A. (1993). DNA-protein interactions. London: Springer. ISBN 978-0-412-25990-6
- ^ “Protein-DNA recognition”. Annu. Rev. Biochem. 53 (1): 293–321. (1984). doi:10.1146/annurev.bi.53.070184.001453. PMID 6236744.
- ^ Dickerson R.E. (1983). “The DNA helix and how it is read”. Sci Am 249 (6): 94–111. Bibcode: 1983SciAm.249f..94D. doi:10.1038/scientificamerican1283-94.
- ^ “Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material”. Prog. Biophys. Mol. Biol. 47 (1): 31–112. (1986). doi:10.1016/0079-6107(86)90005-2. PMID 2422697.
- ^ Dervan PB (April 1986). “Design of sequence-specific DNA-binding molecules”. Science 232 (4749): 464–71. Bibcode: 1986Sci...232..464D. doi:10.1126/science.2421408. PMID 2421408.
- ^ “Minor groove-binding architectural proteins: structure, function, and DNA recognition”. Annu Rev Biophys Biomol Struct 27: 105–31. (1998). doi:10.1146/annurev.biophys.27.1.105. PMC 4781445. PMID 9646864.
- ^ Ganji, Mahipal; Docter, Margreet; Le Grice, Stuart F. J.; Abbondanzieri, Elio A. (2016-09-30). “DNA binding proteins explore multiple local configurations during docking via rapid rebinding”. Nucleic Acids Research 44 (17): 8376–8384. doi:10.1093/nar/gkw666. ISSN 0305-1048. PMC 5041478. PMID 27471033.
- ^ “A TALE of two nucleases: gene targeting for the masses?”. Zebrafish 8 (3): 147–9. (September 2011). doi:10.1089/zeb.2011.9993. PMC 3174730. PMID 21929364.
- ^ “Advances in the study of protein–DNA interaction”. Amino Acids 43 (3): 1141–6. (July 2012). doi:10.1007/s00726-012-1377-9. PMID 22842750.
- ^ Ganji, Mahipal; Docter, Margreet; Grice, Stuart F.J. Le; Abbondanzieri, Elio A. (2016-09-30). “DNA binding proteins explore multiple local configurations during docking via rapid rebinding” (英語). Nucleic Acids Research 44 (17): 8376–8384. doi:10.1093/nar/gkw666. ISSN 0305-1048. PMC 5041478. PMID 27471033.
- ^ Hianik, T. and Wang, J. (2009), Electrochemical Aptasensors – Recent Achievements and Perspectives. Electroanalysis, 21: 1223–1235. doi:10.1002/elan.200904566
- ^ Gosai, A. et al. (2016) Electrical Stimulus Controlled Binding/Unbinding of Human Thrombin-Aptamer Complex. Sci. Rep. 6, 37449; doi:10.1038/srep37449 PMC 5118750
- ^ “Diversity of prokaryotic chromosomal proteins and the origin of the nucleosome”. Cell Mol Life Sci 54 (12): 1350–64. (1998). doi:10.1007/s000180050259. PMID 9893710.
- ^ Dame RT (2005). “The role of nucleoid-associated proteins in the organization and compaction of bacterial chromatin”. Mol. Microbiol. 56 (4): 858–70. doi:10.1111/j.1365-2958.2005.04598.x. PMID 15853876.
- ^ “Crystal structure of the nucleosome core particle at 2.8 A resolution”. Nature 389 (6648): 251–60. (1997). Bibcode: 1997Natur.389..251L. doi:10.1038/38444. PMID 9305837.
- ^ “Translating the histone code”. Science 293 (5532): 1074–80. (2001). doi:10.1126/science.1063127. PMID 11498575.
- ^ Ito T (2003). Nucleosome assembly and remodelling. Current Topics in Microbiology and Immunology. 274. 1–22. doi:10.1007/978-3-642-55747-7_1. ISBN 978-3-642-62909-9. PMID 12596902
- ^ Thomas J (2001). “HMG1 and 2: architectural DNA-binding proteins”. Biochem Soc Trans 29 (Pt 4): 395–401. doi:10.1042/BST0290395. PMID 11497996.
- ^ Murugesapillai, Divakaran; McCauley, Micah J.; Huo, Ran; Nelson Holte, Molly H.; Stepanyants, Armen; Maher, L. James; Israeloff, Nathan E.; Williams, Mark C. (2014). “DNA bridging and looping by HMO1 provides a mechanism for stabilizing nucleosome-free chromatin”. Nucleic Acids Research 42 (14): 8996–9004. doi:10.1093/nar/gku635. PMC 4132745. PMID 25063301.
- ^ Murugesapillai, Divakaran; McCauley, Micah J.; Maher, L. James; Williams, Mark C. (2017). “Single-molecule studies of high-mobility group B architectural DNA bending proteins”. Biophysical Reviews 9: 17–40. doi:10.1007/s12551-016-0236-4. PMC 5331113. PMID 28303166.
- ^ “HMG domain proteins: architectural elements in the assembly of nucleoprotein structures”. Trends Genet 10 (3): 94–100. (1994). doi:10.1016/0168-9525(94)90232-1. PMID 8178371.
- ^ “Replication protein A (RPA): the eukaryotic SSB”. Crit Rev Biochem Mol Biol 34 (3): 141–80. (1999). doi:10.1080/10409239991209255. PMID 10473346.
- ^ “Mediator of transcriptional regulation”. Annu Rev Biochem 69 (1): 729–49. (2000). doi:10.1146/annurev.biochem.69.1.729. PMID 10966474.
- ^ “Biological control throughs regulated transcriptional coactivators”. Cell 119 (2): 157–67. (2004). doi:10.1016/j.cell.2004.09.037. PMID 15479634.
- ^ “A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells”. Proc Natl Acad Sci USA 100 (14): 8164–9. (2003). Bibcode: 2003PNAS..100.8164L. doi:10.1073/pnas.1332764100. PMC 166200. PMID 12808131.
- ^ “Protein-DNA recognition”. Annu Rev Biochem 53 (1): 293–321. (1984). doi:10.1146/annurev.bi.53.070184.001453. PMID 6236744.
- ^ Teif V.B.; Rippe K. (2010). “Statistical-mechanical lattice models for protein-DNA binding in chromatin.”. Journal of Physics: Condensed Matter 22 (41): 414105. arXiv:1004.5514. Bibcode: 2010JPCM...22O4105T. doi:10.1088/0953-8984/22/41/414105. PMID 21386588.
- ^ Wong KC, Chan TM, Peng C., Li Y., and Zhang Z. "DNA Motif Elucidation using belief propagation" Nucleic Acids Research Advanced Online June 2013; doi:10.1093/nar/gkt574 PMID 23814189
[続きの解説]
「DNA結合タンパク質」の続きの解説一覧
- 1 DNA結合タンパク質とは
- 2 DNA結合タンパク質の概要
- 3 関連項目
- DNA結合タンパク質のページへのリンク
