胆汁酸-7α-デヒドロキシラーゼ
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2025/02/12 16:30 UTC 版)
| 胆汁酸-7α-デヒドロキシラーゼ | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 識別子 | |||||||||
| EC番号 | 1.17.99.5 | ||||||||
| CAS登録番号 | 85130-33-2 | ||||||||
| データベース | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB構造 | RCSB PDB PDBj PDBe PDBsum | ||||||||
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胆汁酸-7α-デヒドロキシラーゼ(bile-acid 7α-dehydroxylase)は、二次胆汁酸生合成酵素の一つで、次の化学反応を触媒する酸化還元酵素である。
脚注
参考文献
- White, B.A., Cacciapuoti, A.F., Fricke, R.J., Whitehead, T.R., Mosbach, E.H. and Hylemon, P.B. (1981). “Cofactor requirements for 7α-dehydroxylation of cholic and chenodeoxycholic acid in cell extracts of the intestinal anaerobic bacterium, Eubacterium species V.P.I. 12708.”. J. Lipid Res. 22: 891-898. PMID 7276750.
- White, B.A., Paone, D.A., Cacciapuoti, A.F., Fricke, R.J., Mosbach, E.H. and Hylemon, P.B. (1983). “Regulation of bile acid 7-dehydroxylase activity by NAD+ and NADH in cell extracts of Eubacterium species V.P.I.12708.”. J. Lipid Res. 24: 20-27. PMID 6833878.
- Coleman, J.P., White, W.B. and Hylemon, P.B. (1987). “Molecular cloning of bile acid 7-dehydroxylase from Eubacterium sp. strain VPI 12708.”. J. Bacteriol. 169: 1516-1521. PMID 3549693.
- Russell, D.W. (2003). “The enzymes, regulation, and genetics of bile acid synthesis.”. Annu. Rev. Biochem. 72: 137-174. PMID 12543708.
- Coleman, J.P., White, W.B., Egestad, B., Sjövall, J. and Hylemon, P.B. (1987). “Biosynthesis of a novel bile acid nucleotide and mechanism of 7α-dehydroxylation by an intestinal Eubacterium species.”. J. Biol. Chem. 262: 4701-4707. PMID 3558364.
- Hylemon, P.B., Melone, P.D., Franklund, C.V., Lund, E. and Björkhem, I. (1991). “Mechanism of intestinal 7α-dehydroxylation of cholic acid: evidence that allo-deoxycholic acid is an inducible side-product.”. J. Lipid Res. 32: 89-96. PMID 2010697.
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