ロタウイルスとは？ わかりやすく解説

Weblio 辞書 > ビジネス > 新語時事用語辞典 > ロタウイルスの意味・解説 
新語時事用語辞典
索引トップ ランキング
新語時事用語辞典新語時事用語辞典

ロタウィルス

別名：ロタウイルス
英語：rotavirus

主に乳幼児に感染し、下痢・嘔吐・胃腸炎などを引き起こすことで知られるウィルス。冬場に感染することが多い。

ロタウイルスには生後数ヵ月から2～3歳頃の乳幼児が罹患することが多い。成人やある程度成長した児童は感染しても顕著な症状が表れないことが多い。乳幼児が感染すると、2日程度の潜伏期間を経て、激しい発熱・嘔吐、白色の便を排出する下痢といった症状が表れる。

ロタウイルスは感染力が強く10個程度のウィルスでも感染するとされている。予防のために有効なワクチンとしては、日本では2011年7月に「ロタリックス」が承認を受けている。

なお、ロタウィルスと同様に感染性の胃腸炎を引き起こすウィルスとして、ノロウィルスなどもよく知られている。
（2011年11月23日更新）

デジタル大辞泉
索引トップ ランキング 凡例
デジタル大辞泉デジタル大辞泉

ロタウイルス【rotavirus】

読み方：ろたういるす

胃腸炎の原因となるウイルス。小児の多くの下痢症（仮性小児コレラ）の原因ウイルス。川崎病患者にも多い。


微生物の用語解説
索引トップ ランキング
微生物管理機構微生物管理機構

ロタウイルス [Rota virus]

　ロタとは車輪の意味でウイルス粒子が車輪に似ているため命名された。ウイルスの伝播は経口感染で、生後6カ月から2歳半ぐらいの乳幼児に好発する。主な流行時期は、11～3月までの冬期である。臨床的には下痢、悪感腹痛、嘔吐発熱などで2日～1週間以内に回復する。ウイルス性食中毒の原因ウイルスです。ワクチンなどの予防法は確立されていない。

ウィキペディア
索引トップ 用語の索引 ランキング カテゴリー
ウィキペディアウィキペディア

ロタウイルス

出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/12/02 07:58 UTC 版)

ロタウイルス（Rotavirus）は、乳幼児における下痢症の主要な病原体である[1]。レオウイルス科に属する二本鎖RNAウイルスの属である。離島国などを除き世界中でほとんどの乳幼児が5 - 6歳までに一度はロタウイルスの感染を経験する[2]。感染のたびに免疫が誘導されるため、回を追うごとに軽症化し、大人は発症しないか、極めて軽微となる。


脚注
  1. ^ Dennehy PH (2015). “Rotavirus Infection: A Disease of the Past?”. Infectious Disease Clinics of North America 29 (4): 617-35. doi:10.1016/j.idc.2015.07.002. PMID 26337738. 
  2. ^ a b Bernstein DI (March 2009). “Rotavirus overview”. The Pediatric Infectious Disease Journal 28 (3 Suppl): S50-3. doi:10.1097/INF.0b013e3181967bee. PMID 19252423. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0891-3668&volume=28&issue=3&spage=S50. 
  3. ^ a b Bishop R (October 2009). “Discovery of rotavirus: Implications for child health”. Journal of Gastroenterology and Hepatology 24 (Suppl 3): S81-5. doi:10.1111/j.1440-1746.2009.06076.x. PMID 19799704. 
  4. ^ a b c Simpson E, Wittet S, Bonilla J, Gamazina K, Cooley L, Winkler JL (2007). “Use of formative research in developing a knowledge translation approach to rotavirus vaccine introduction in developing countries”. BMC Public Health 7: 281. doi:10.1186/1471-2458-7-281. PMC 2173895. PMID 17919334. http://www.biomedcentral.com/1471-2458/7/281. 
  5. ^ a b Edward J Dubovi; Nigel James MacLachlan (2010). Fenner's Veterinary Virology, Fourth Edition. Boston: Academic Press. p. 288. ISBN 0-12-375158-6 
  6. ^ a b Tate, Jacqueline E.; Burton, Anthony H.; Boschi-Pinto, Cynthia; Parashar, Umesh D. (2016). “Global, Regional, and National Estimates of Rotavirus Mortality in Children <5 Years of Age, 2000-2013”. Clinical Infectious Diseases 62 (Suppl 2): S96-S105. http://cid.oxfordjournals.org/content/62/suppl_2/S96.full. 
  7. ^ World Health Organization (2008). “Global networks for surveillance of rotavirus gastroenteritis, 2001-2008”. Weekly Epidemiological Record 83 (47): 421-428. http://www.who.int/wer/2008/wer8347.pdf 2012年5月3日閲覧。. 
  8. ^ Fischer TK, Viboud C, Parashar U, etal (2007). “Hospitalizations and deaths from diarrhea and rotavirus among children <5 years of age in the United States, 1993-2003”. J. Infect. Dis. 195 (8): 1117-25. doi:10.1086/512863. PMID 17357047. 
  9. ^ a b Leshem, Eyal; Moritz, Rebecca E.; Curns, Aaron T.; et al. (2014). “Rotavirus Vaccines and Health Care Utilization for Diarrhea in the United States (2007-2011)”. Pediatrics 134 (1): 15-23. http://pediatrics.aappublications.org/content/134/1/15. 
  10. ^ Tate JE, Cortese MM, Payne DC, Curns AT, Yen C, Esposito DH, Cortes JE, Lopman BA, Patel MM, Gentsch JR, Parashar UD (January 2011). “Uptake, impact, and effectiveness of rotavirus vaccination in the United States: review of the first 3 years of postlicensure data”. The Pediatric Infectious Disease Journal 30 (1 Suppl): S56-60. doi:10.1097/INF.0b013e3181fefdc0. PMID 21183842. 
  11. ^ a b Diggle L (2007). “Rotavirus diarrhea and future prospects for prevention”. Br. J. Nurs. 16 (16): 970-4. PMID 18026034. 
  12. ^ a b Giaquinto C, Dominiak-Felden G, Van Damme P, Myint TT, Maldonado YA, Spoulou V, Mast TC, Staat MA (July 2011). “Summary of effectiveness and impact of rotavirus vaccination with the oral pentavalent rotavirus vaccine: a systematic review of the experience in industrialized countries”. Human Vaccines 7 (7): 734-48. doi:10.4161/hv.7.7.15511. PMID 21734466. http://www.landesbioscience.com/journals/hv/abstract.php?id=15511. 
  13. ^ a b c d Jiang V, Jiang B, Tate J, Parashar UD, Patel MM (July 2010). “Performance of rotavirus vaccines in developed and developing countries”. Human Vaccines 6 (7): 532-42. doi:10.4161/hv.6.7.11278. PMC 3322519. PMID 20622508. http://www.landesbioscience.com/journals/hv/abstract.php?id=11278. 
  14. ^ a b c Parashar, Umesh D.; Tate, Jacqueline E., eds (2016). “Health Benefits of Rotavirus Vaccination in Developing Countries”. Clinical Infectious Diseases 62 (Suppl 2): S91-S228. http://cid.oxfordjournals.org/content/62/suppl_2.toc. 
  15. ^ Virus Taxonomy: 2014 Release, International Committee on Taxonomy of Viruses (ICTV), http://ictvonline.org/virustaxonomy.asp 
  16. ^ a b c “ロタウイルス感染性胃腸炎とは”. 国立感染症研究所. 2017年2月2日閲覧。
  17. ^ Wakuda M, Ide T, Sasaki J, Komoto S, Ishii J, Sanekata T, Taniguchi K (2011). “Porcine rotavirus closely related to novel group of human rotaviruses”. Emerging Infectious Diseases 17 (8): 1491-3. doi:10.3201/eid1708.101466. PMC 3381553. PMID 21801631. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381553/. 
  18. ^ Marthaler D, Rossow K, Culhane M, Goyal S, Collins J, Matthijnssens J, Nelson M, Ciarlet M (2014). “Widespread rotavirus H in commercially raised pigs, United States”. Emerging Infectious Diseases 20 (7): 1195-8. doi:10.3201/eid2007.140034. PMC 4073875. PMID 24960190. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073875/. 
  19. ^ O'Ryan M (March 2009). “The ever-changing landscape of rotavirus serotypes”. The Pediatric Infectious Disease Journal 28 (3 Suppl): S60-2. doi:10.1097/INF.0b013e3181967c29. PMID 19252426. 
  20. ^ Patton JT (January 2012). “Rotavirus diversity and evolution in the post-vaccine world”. Discovery Medicine 13 (68): 85-97. PMC 3738915. PMID 22284787. http://www.discoverymedicine.com/John-T-Patton/2012/01/26/rotavirus-diversity-and-evolution-in-the-post-vaccine-world/. 
  21. ^ Desselberger U, Wolleswinkel-van den Bosch J, Mrukowicz J, Rodrigo C, Giaquinto C, Vesikari T (2006). “Rotavirus types in Europe and their significance for vaccination”. Pediatr. Infect. Dis. J. 25 (1 Suppl.): S30-41. doi:10.1097/01.inf.0000197707.70835.f3. PMID 16397427. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?an=00006454-200601001-00005. 
  22. ^ Phan MVT, Anh PH, Cuong NV, Munnink BBO, van der Hoek L, My PT, Tri TN, Bryant JE, Baker S, Thwaites G, Woolhouse M, Kellam P, Rabaa MA, Cotten M (2016). “Unbiased whole-genome deep sequencing of human and porcine stool samples reveals circulation of multiple groups of rotaviruses and a putative zoonotic infection”. Virus Evolution 2 (2). doi:10.1093/ve/vew027. PMC 5522372. PMID 28748110. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522372/. 
  23. ^ 小林宣道「全遺伝子配列に基づくヒトロタウイルスの遺伝子型別とその世界的な動向」『IASR』第35巻、2014年、66-7頁。 
  24. ^ Beards GM, Desselberger U, Flewett TH (1989). “Temporal and geographical distributions of human rotavirus serotypes, 1983 to 1988”. Journal of Clinical Microbiology 27 (12): 2827-33. PMC 267135. PMID 2556435. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC267135/. 
  25. ^ Desselberger, U.; Gray, James (2000). Desselberger, U.; Gray, James. eds. Rotaviruses: methods and protocols. Totowa, NJ: Humana Press. p. 2. ISBN 0-89603-736-3 
  26. ^ a b c d e f g 平松啓一・中込治 編『標準微生物学』（第10版）医学書院、2009年、426-434頁。ISBN 978-4-260-00638-5。 
  27. ^ a b Pesavento JB, Crawford SE, Estes MK, Prasad BV (2006). “Rotavirus proteins: structure and assembly”. Curr. Top. Microbiol. Immunol.. Current Topics in Microbiology and Immunology 309: 189-219. doi:10.1007/3-540-30773-7_7. ISBN 978-3-540-30772-3. PMID 16913048. 
  28. ^ Prasad BV, Chiu W (1994). “Structure of rotavirus”. Curr. Top. Microbiol. Immunol. 185: 9-29. PMID 8050286. 
  29. ^ Kirkwood CD (September 2010). “Genetic and antigenic diversity of human rotaviruses: potential impact on vaccination programs”. The Journal of Infectious Diseases 202 (Suppl): S43-8. doi:10.1086/653548. PMID 20684716. 
  30. ^ Patton JT (1995). “Structure and function of the rotavirus RNA-binding proteins” (PDF). J. Gen. Virol. 76 (11): 2633-44. doi:10.1099/0022-1317-76-11-2633. PMID 7595370. オリジナルの2012年12月9日時点におけるアーカイブ。. https://archive.is/20121209041049/http://vir.sgmjournals.org/cgi/reprint/76/11/2633. 
  31. ^ Patton JT (2001). “Rotavirus RNA replication and gene expression”. Novartis Found. Symp.. Novartis Foundation Symposia 238: 64-77; discussion 77-81. doi:10.1002/0470846534.ch5. ISBN 9780470846537. PMID 11444036. 
  32. ^ Vásquez-del Carpió R, Morales JL, Barro M, Ricardo A, Spencer E (2006). “Bioinformatic prediction of polymerase elements in the rotavirus VP1 protein”. Biol. Res. 39 (4): 649-59. doi:10.4067/S0716-97602006000500008. PMID 17657346. http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000500008&tlng=en&lng=en&nrm=iso. 
  33. ^ Arnoldi F, Campagna M, Eichwald C, Desselberger U, Burrone OR (2007). “Interaction of rotavirus polymerase VP1 with nonstructural protein NSP5 is stronger than that with NSP2”. J. Virol. 81 (5): 2128-37. doi:10.1128/JVI.01494-06. PMC 1865955. PMID 17182692. http://jvi.asm.org/cgi/content/full/81/5/2128. 
  34. ^ a b Angel J, Franco MA, Greenberg HB (2009). Desk Encyclopedia of Human and Medical Virology. Boston: Academic Press. p. 277. ISBN 0-12-375147-0 
  35. ^ Cowling VH (January 2010). “Regulation of mRNA cap methylation”. Biochem. J. 425 (2): 295-302. doi:10.1042/BJ20091352. PMC 2825737. PMID 20025612. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825737/. 
  36. ^ Gardet A, Breton M, Fontanges P, Trugnan G, Chwetzoff S (2006). “Rotavirus spike protein VP4 binds to and remodels actin bundles of the epithelial brush border into actin bodies”. J. Virol. 80 (8): 3947-56. doi:10.1128/JVI.80.8.3947-3956.2006. PMC 1440440. PMID 16571811. http://jvi.asm.org/cgi/content/full/80/8/3947. 
  37. ^ Arias CF, Isa P, Guerrero CA, Méndez E, Zárate S, López T, Espinosa R, Romero P, López S (2002). “Molecular biology of rotavirus cell entry”. Arch. Med. Res. 33 (4): 356-61. doi:10.1016/S0188-4409(02)00374-0. PMID 12234525. 
  38. ^ a b Jayaram H, Estes MK, Prasad BV (April 2004). “Emerging themes in rotavirus cell entry, genome organization, transcription and replication”. Virus Research 101 (1): 67-81. doi:10.1016/j.virusres.2003.12.007. PMID 15010218. 
  39. ^ Hoshino Y, Jones RW, Kapikian AZ (2002). “Characterization of neutralization specificities of outer capsid spike protein VP4 of selected murine, lapine, and human rotavirus strains”. Virology 299 (1): 64-71. doi:10.1006/viro.2002.1474. PMID 12167342. 
  40. ^ 白土(堀越)東子、武田直和「ノロウイルスと血液型抗原」『ウイルス』第57巻第2号、2007年、181-190頁、doi:10.2222/jsv.57.181、NAID 10020283626。 
  41. ^ Van Trang N, Vu HT, Le NT, Huang P, Jiang X, Anh DD (2014). “Association between norovirus and rotavirus infection and histo-blood group antigen types in Vietnamese children”. Journal of Clinical Microbiology 52 (5): 1366-74. doi:10.1128/JCM.02927-13. PMC 3993640. PMID 24523471. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993640/. 
  42. ^ a b c Bishop RF (1996). “Natural history of human rotavirus infection”. Arch. Virol. Suppl. 12: 119-28. PMID 9015109. 
  43. ^ Beards GM, Campbell AD, Cottrell NR, Peiris JS, Rees N, Sanders RC, Shirley JA, Wood HC, Flewett TH (1 February 1984). “Enzyme-linked immunosorbent assays based on polyclonal and monoclonal antibodies for rotavirus detection” (PDF). J. Clin. Microbiol. 19 (2): 248-54. PMC 271031. PMID 6321549. http://jcm.asm.org/cgi/reprint/19/2/248. 
  44. ^ Hua J, Mansell EA, Patton JT (1993). “Comparative analysis of the rotavirus NS53 gene: conservation of basic and cysteine-rich regions in the protein and possible stem-loop structures in the RNA”. Virology 196 (1): 372-8. doi:10.1006/viro.1993.1492. PMID 8395125. 
  45. ^ Arnold MM (2016). “The Rotavirus Interferon Antagonist NSP1: Many Targets, Many Questions”. Journal of Virology 90 (11): 5212-5. doi:10.1128/JVI.03068-15. PMID 27009959. 
  46. ^ Kattoura MD, Chen X, Patton JT (1994). “The rotavirus RNA-binding protein NS35 (NSP2) forms 10S multimers and interacts with the viral RNA polymerase”. Virology 202 (2): 803-13. doi:10.1006/viro.1994.1402. PMID 8030243. 
  47. ^ Taraporewala ZF, Patton JT (2004). “Nonstructural proteins involved in genome packaging and replication of rotaviruses and other members of the Reoviridae”. Virus Res. 101 (1): 57-66. doi:10.1016/j.virusres.2003.12.006. PMID 15010217. 
  48. ^ Poncet D, Aponte C, Cohen J (1 June 1993). “Rotavirus protein NSP3 (NS34) is bound to the 3' end consensus sequence of viral mRNAs in infected cells” (PDF). J. Virol. 67 (6): 3159-65. PMC 237654. PMID 8388495. http://jvi.asm.org/cgi/reprint/67/6/3159. 
  49. ^ López, S; Arias, CF (August 2012). “Rotavirus-host cell interactions: an arms race.”. Current Opinion in Virology 2 (4): 389-98. doi:10.1016/j.coviro.2012.05.001. PMID 22658208. 
  50. ^ a b Hyser JM, Estes MK (January 2009). “Rotavirus vaccines and pathogenesis: 2008”. Current Opinion in Gastroenterology 25 (1): 36-43. doi:10.1097/MOG.0b013e328317c897. PMC 2673536. PMID 19114772. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0267-1379&volume=25&issue=1&spage=36. 
  51. ^ Afrikanova I, Miozzo MC, Giambiagi S, Burrone O (1996). “Phosphorylation generates different forms of rotavirus NSP5”. J. Gen. Virol. 77 (9): 2059-65. doi:10.1099/0022-1317-77-9-2059. PMID 8811003. オリジナルの2012年5月26日時点におけるアーカイブ。. https://archive.is/20120526030014/http://vir.sgmjournals.org/cgi/reprint/77/9/2059. 
  52. ^ Rainsford EW, McCrae MA (2007). “Characterization of the NSP6 protein product of rotavirus gene 11”. Virus Res. 130 (1-2): 193-201. doi:10.1016/j.virusres.2007.06.011. PMID 17658646. 
  53. ^ Mohan KV, Atreya CD (2001). “Nucleotide sequence analysis of rotavirus gene 11 from two tissue culture-adapted ATCC strains, RRV and Wa”. Virus Genes 23 (3): 321-9. doi:10.1023/A:1012577407824. PMID 11778700. 
  54. ^ Desselberger U. Rotavirus: basic facts. In Rotaviruses Methods and Protocols. Ed. Gray, J. and Desselberger U. Humana Press, 2000, pp. 1-8. ISBN 0-89603-736-3
  55. ^ Patton JT. Rotavirus RNA replication and gene expression. In Novartis Foundation. Gastroenteritis Viruses, Humana Press, 2001, pp. 64-81. ISBN 0-471-49663-4
  56. ^ Claude M. Fauquet; J. Maniloff; Desselberger, U. (2005). Virus taxonomy: classification and nomenclature of viruses: 8th report of the International Committee on Taxonomy of Viruses. Amsterdam: Elsevier/Academic Press. pp. 489. ISBN 0-12-249951-4 
  57. ^ a b Greenberg HB, Estes MK (May 2009). “Rotaviruses: from pathogenesis to vaccination”. Gastroenterology 136 (6): 1939-51. doi:10.1053/j.gastro.2009.02.076. PMC 3690811. PMID 19457420. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690811/. 
  58. ^ a b Greenberg HB, Clark HF, Offit PA (1994). “Rotavirus pathology and pathophysiology”. Curr. Top. Microbiol. Immunol. 185: 255-83. PMID 8050281. 
  59. ^ Baker M, Prasad BV (2010). “Rotavirus cell entry”. Current Topics in Microbiology and Immunology. Current Topics in Microbiology and Immunology 343: 121-48. doi:10.1007/82_2010_34. ISBN 978-3-642-13331-2. PMID 20397068. 
  60. ^ Silvestri LS, Taraporewala ZF, Patton JT (2004). “Rotavirus replication: plus-sense templates for double-stranded RNA synthesis are made in viroplasms”. Journal of Virology 78 (14): 7763-74. doi:10.1128/JVI.78.14.7763-7774.2004. PMC 434085. PMID 15220450. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC434085/. 
  61. ^ Patton JT, Vasquez-Del Carpio R, Spencer E (2004). “Replication and transcription of the rotavirus genome”. Curr. Pharm. Des. 10 (30): 3769-77. doi:10.2174/1381612043382620. PMID 15579070. 
  62. ^ Ruiz MC, Leon T, Diaz Y, Michelangeli F (2009). “Molecular biology of rotavirus entry and replication”. TheScientificWorldJournal 9: 1476-97. doi:10.1100/tsw.2009.158. PMID 20024520. 
  63. ^ Butz AM, Fosarelli P, Dick J, Cusack T, Yolken R (1993). “Prevalence of rotavirus on high-risk fomites in day-care facilities”. Pediatrics 92 (2): 202-5. PMID 8393172. 
  64. ^ a b Dennehy PH (2000). “Transmission of rotavirus and other enteric pathogens in the home”. Pediatr. Infect. Dis. J. 19 (10 Suppl): S103-5. doi:10.1097/00006454-200010001-00003. PMID 11052397. 
  65. ^ a b Grimwood K, Lambert SB (February 2009). “Rotavirus vaccines: opportunities and challenges”. Human Vaccines 5 (2): 57-69. doi:10.4161/hv.5.2.6924. PMID 18838873. http://www.landesbioscience.com/journals/hv/abstract.php?id=6924. 
  66. ^ Hochwald C, Kivela L (1999). “Rotavirus vaccine, live, oral, tetravalent (RotaShield)”. Pediatr. Nurs. 25 (2): 203-4, 207. PMID 10532018. 
  67. ^ Maldonado YA, Yolken RH (1990). “Rotavirus”. Baillieres Clin. Gastroenterol. 4 (3): 609-25. doi:10.1016/0950-3528(90)90052-I. PMID 1962726. 
  68. ^ Glass RI, Parashar UD, Bresee JS, Turcios R, Fischer TK, Widdowson MA, Jiang B, Gentsch JR (July 2006). “Rotavirus vaccines: current prospects and future challenges”. Lancet 368 (9532): 323-32. doi:10.1016/S0140-6736(06)68815-6. PMID 16860702. 
  69. ^ Offit PA (2001). Gastroenteritis viruses. New York: Wiley. pp. 106-124. ISBN 0-471-49663-4 
  70. ^ Ward R (March 2009). “Mechanisms of protection against rotavirus infection and disease”. The Pediatric Infectious Disease Journal 28 (3 Suppl): S57-9. doi:10.1097/INF.0b013e3181967c16. PMID 19252425. 
  71. ^ Ramsay M, Brown D (2000). Desselberger, U.; Gray, James. eds. Rotaviruses: methods and protocols. Totowa, NJ: Humana Press. p. 217. ISBN 0-89603-736-3 Free ebook [1]
  72. ^ Hrdy DB (1987). “Epidemiology of rotaviral infection in adults”. Rev. Infect. Dis. 9 (3): 461-9. doi:10.1093/clinids/9.3.461. PMID 3037675. 
  73. ^ Rodríguez-Díaz J, García-Mantrana I, Vila-Vicent S, Gozalbo-Rovira R, Buesa J, Monedero V, Collado MC (2017). “Relevance of secretor status genotype and microbiota composition in susceptibility to rotavirus and norovirus infections in humans”. Scientific Reports 7: 45559. doi:10.1038/srep45559. PMC 5372083. PMID 28358023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372083/. 
  74. ^ “Rotavirus viremia and extraintestinal viral infection in the neonatal rat model”. Journal of Virology 80 (10): 4820-32. (2006). doi:10.1128/JVI.80.10.4820-4832.2006. PMC 1472071. PMID 16641274. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472071/. 
  75. ^ Farnworth ER (June 2008). “The evidence to support health claims for probiotics”. The Journal of Nutrition 138 (6): 1250S-4S. PMID 18492865. http://jn.nutrition.org/cgi/pmidlookup?view=long&pmid=18492865. 
  76. ^ Ouwehand A, Vesterlund S (2003). “Health aspects of probiotics”. IDrugs 6 (6): 573-80. PMID 12811680. 
  77. ^ Arya SC (1984). “Rotaviral infection and intestinal lactase level”. J. Infect. Dis. 150 (5): 791. doi:10.1093/infdis/150.5.791. PMID 6436397. 
  78. ^ a b Patel MM, Tate JE, Selvarangan R, Daskalaki I, Jackson MA, Curns AT, Coffin S, Watson B, Hodinka R, Glass RI, Parashar UD (October 2007). “Routine laboratory testing data for surveillance of rotavirus hospitalizations to evaluate the impact of vaccination”. The Pediatric Infectious Disease Journal 26 (10): 914-9. doi:10.1097/INF.0b013e31812e52fd. PMID 17901797. 
  79. ^ The Pediatric ROTavirus European CommitTee (PROTECT) (2006). “The paediatric burden of rotavirus disease in Europe”. Epidemiol. Infect. 134 (5): 908-16. doi:10.1017/S0950268806006091. PMC 2870494. PMID 16650331. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870494/. 
  80. ^ Goode, Jamie; Chadwick, Derek (2001). Gastroenteritis viruses. New York: Wiley. p. 14. ISBN 0-471-49663-4 
  81. ^ Fischer TK, Gentsch JR (2004). “Rotavirus typing methods and algorithms”. Reviews in Medical Virology 14 (2): 71-82. doi:10.1002/rmv.411. PMID 15027000. 
  82. ^ Alam NH, Ashraf H (2003). “Treatment of infectious diarrhea in children”. Paediatr. Drugs 5 (3): 151-65. doi:10.2165/00128072-200305030-00002. PMID 12608880. 
  83. ^ Sachdev HP (1996). “Oral rehydration therapy”. Journal of the Indian Medical Association 94 (8): 298-305. PMID 8855579. 
  84. ^ World Health Organization, UNICEF. “Joint Statement: Clinical Management of Acute Diarrhoea”. 2012年5月3日閲覧。
  85. ^ Ahmadi E, Alizadeh-Navaei R, Rezai MS (2015). “Efficacy of probiotic use in acute rotavirus diarrhea in children: A systematic review and meta-analysis”. Caspian J Intern Med 6 (4): 187-95. 
  86. ^ Guarino A1, Ashkenazi S, Gendrel D, Lo Vecchio A, Shamir R, Szajewska H (2014). “European Society for Pediatric Gastroenterology, Hepatology, and Nutrition/European Society for Pediatric Infectious Diseases evidence-based guidelines for the management of acute gastroenteritis in children in Europe: update 2014.”. J Pediatr Gastroenterol Nutr 59 (1): 132-52. doi:10.1097/mpg.0000000000000375. 
  87. ^ Ramig RF (August 2007). “Systemic rotavirus infection”. Expert Review of Anti-infective Therapy 5 (4): 591-612. doi:10.1586/14787210.5.4.591. PMID 17678424. 
  88. ^ ロタウイルス感染に関連した急性脳症の 1例 日大医学雑誌 Vol.67 (2008) No.5 P304-308
  89. ^ O'Ryan M (2007). “Rotarix (RIX4414): an oral human rotavirus vaccine”. Expert review of vaccines 6 (1): 11-9. doi:10.1586/14760584.6.1.11. PMID 17280473. 
  90. ^ Matson DO (2006). “The pentavalent rotavirus vaccine, RotaTeq”. Seminars in paediatric infectious diseases 17 (4): 195-9. doi:10.1053/j.spid.2006.08.005. PMID 17055370. 
  91. ^ 谷口 孝喜：ヒトロタウイルスワクチン ウイルス Vol.62 (2012) No.1 p.87-96
  92. ^ Soares-Weiser K, Maclehose H, Bergman H, et al. (2012). Soares-Weiser, Karla. ed. “Vaccines for preventing rotavirus diarrhoea: vaccines in use”. Cochrane Database Syst Rev 11: CD008521. doi:10.1002/14651858.CD008521.pub3. PMID 23152260. 
  93. ^ 河島尚志、渡邉知愛子、五百井寛明、「ロタウイルスの最近の話題」 モダンメディア 2006年12月号（第52巻12号）
  94. ^ Rota Council (2016). Rotavirus: Common, Severe, Devastating, Preventable. http://rotacouncil.org/resources/White-paper-FINAL-v2.pdf 
  95. ^ ロタウイルス最新ワクチンに高い有効性、アフリカの子どもに希望の光 AFP（2017年3月23日）2017年3月27日閲覧
  96. ^ Ward RL, Clark HF, Offit PA (September 2010). “Influence of potential protective mechanisms on the development of live rotavirus vaccines”. The Journal of Infectious Diseases 202 (Suppl): S72-9. doi:10.1086/653549. PMID 20684721. http://www.jid.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=20684721. 
  97. ^ Tate JE, Patel MM, Steele AD, Gentsch JR, Payne DC, Cortese MM, Nakagomi O, Cunliffe NA, Jiang B, Neuzil KM, de Oliveira LH, Glass RI, Parashar UD (April 2010). “Global impact of rotavirus vaccines”. Expert Review of Vaccines 9 (4): 395-407. doi:10.1586/erv.10.17. PMID 20370550. 
  98. ^ Tate, Jacqueline E.; Parashar, Umesh D. (2014). “Rotavirus Vaccines in Routine Use”. Clinical Infectious Diseases 59 (9): 1291-1301. http://cid.oxfordjournals.org/content/59/9/1291. 
  99. ^ Richardson, V; Hernandez-Pichardo J; Quintanar-Solares M; et al. (2010). “Effect of Rotavirus Vaccination on Death From Childhood Diarrhea in Mexico”. The New England Journal of Medicine 362 (4): 299-305. doi:10.1056/NEJMoa0905211. PMID 20107215. 
  100. ^ Patel M, Pedreira C, De Oliveira LH, etal (August 2012). “Duration of protection of pentavalent rotavirus vaccination in Nicaragua”. Pediatrics 130 (2): e365-72. doi:10.1542/peds.2011-3478. PMID 22753550. 
  101. ^ Tate JE, Mutuc JD, Panozzo CA, Payne DC, Cortese MM, Cortes JE, Yen C, Esposito DH, Lopman BA, Patel MM, Parashar UD (January 2011). “Sustained decline in rotavirus detections in the United States following the introduction of rotavirus vaccine in 2006.”. Pediatric Infectious Disease Journal 30 (1 Supplement): S30-4. doi:10.1097/INF.0b013e3181ffe3eb.. PMID 21183838. 
  102. ^ Patel MM, Parashar UD, eds. (January 2011). “Real World Impact of Rotavirus Vaccination”. Pediatric Infectious Disease Journal 30 (Supplement): S1. doi:10.1097/INF.0b013e3181fefa1f. PMID 21183833. http://journals.lww.com/pidj/toc/2011/01001 2012年5月8日閲覧。. 
  103. ^ Steele, A. Duncan; Armah, George E.; Page, Nicola A. et al., eds (2010). “Rotavirus Infection in Africa: Epidemiology, Burden of Disease, and Strain Diversity”. Journal of Infectious Diseases 202 (Suppl 1): S1-S265. http://jid.oxfordjournals.org/content/202/Supplement_1.toc. 
  104. ^ Nelson, E. Anthony S.; Widdowson, Marc-Alain; Kilgore, Paul E. et al., eds (2009). “Rotavirus in Asia: Updates on Disease Burden, Genotypes and Vaccine Introduction”. Vaccine 27 (Suppl 5): F1-F138. http://www.sciencedirect.com/science/journal/0264410X/27/supp/S5. 
  105. ^ World Health Organization (December 2009). “Rotavirus vaccines: an update”. Weekly Epidemiological Record 51-52 (84): 533-540. http://www.who.int/wer/2009/wer8451_52.pdf 2012年5月8日閲覧。. 
  106. ^ UK Department of Health: New vaccine to help protect babies against rotavirus. Retrieved on 10 November, 2012
  107. ^ Karafillakis E, Hassounah S, Atchison C (2015). “Effectiveness and impact of rotavirus vaccines in Europe, 2006-2014”. Vaccine 33 (18): 2097-107. doi:10.1016/j.vaccine.2015.03.016. PMID 25795258. 
  108. ^ “Rotavirus Deaths & Rotavirus Vaccine Introduction Maps - ROTA Council”. rotacouncil.org. 2016年7月12日時点のオリジナルよりアーカイブ。2016年7月29日閲覧。
  109. ^ Moszynski P (2011). “GAVI rolls out vaccines against child killers to more countries”. BMJ (Clinical Research Ed.) 343: d6217. doi:10.1136/bmj.d6217. PMID 21957215. http://www.bmj.com/cgi/pmidlookup?view=long&pmid=21957215. 
  110. ^ Leung AK, Kellner JD, Davies HD (2005). “Rotavirus gastroenteritis”. Adv. Ther. 22 (5): 476-87. doi:10.1007/BF02849868. PMID 16418157. 
  111. ^ Parashar UD, Gibson CJ, Bresse JS, Glass RI (2006). “Rotavirus and severe childhood diarrhea”. Emerging Infect. Dis. 12 (2): 304-6. doi:10.3201/eid1202.050006. PMC 3373114. PMID 16494759. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373114/. 
  112. ^ Tate JE, Burton AH, Boschi-Pinto C, Steele AD, Duque J, Parashar UD (February 2012). “2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis”. Lancet Infect Dis 12 (2): 136-141. doi:10.1016/S1473-3099(11)70253-5. PMID 22030330. 
  113. ^ Rheingans RD, Heylen J, Giaquinto C (2006). “Economics of rotavirus gastroenteritis and vaccination in Europe: what makes sense?”. Pediatr. Infect. Dis. J. 25 (1 Suppl): S48-55. doi:10.1097/01.inf.0000197566.47750.3d. PMID 16397429. 
  114. ^ Ryan MJ, Ramsay M, Brown D, Gay NJ, Farrington CP, Wall PG (1996). “Hospital admissions attributable to rotavirus infection in England and Wales”. J. Infect. Dis. 174 (Suppl 1): S12-8. doi:10.1093/infdis/174.Supplement_1.S12. PMID 8752285. 
  115. ^ Atchison CJ, Tam CC, Hajat S, van Pelt W, Cowden JM, Lopman BA (March 2010). “Temperature-dependent transmission of rotavirus in Great Britain and The Netherlands”. Proceedings of the Royal Society B: Biological Sciences 277 (1683): 933-42. doi:10.1098/rspb.2009.1755. PMC 2842727. PMID 19939844. http://rspb.royalsocietypublishing.org/cgi/pmidlookup?view=long&pmid=19939844. 
  116. ^ Levy K, Hubbard AE, Eisenberg JN (December 2009). “Seasonality of rotavirus disease in the tropics: a systematic review and meta-analysis”. International Journal of Epidemiology 38 (6): 1487-96. doi:10.1093/ije/dyn260. PMC 2800782. PMID 19056806. http://ije.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=19056806. 
  117. ^ Koopmans M, Brown D (1999). “Seasonality and diversity of Group A rotaviruses in Europe”. Acta Paediatrica Supplement 88 (426): 14-9. doi:10.1111/j.1651-2227.1999.tb14320.x. PMID 10088906. 
  118. ^ Anderson EJ, Weber SG (February 2004). “Rotavirus infection in adults”. The Lancet Infectious Diseases 4 (2): 91-9. doi:10.1016/S1473-3099(04)00928-4. PMID 14871633. http://linkinghub.elsevier.com/retrieve/pii/S1473309904009284. 
  119. ^ Hopkins RS, Gaspard GB, Williams FP, Karlin RJ, Cukor G, Blacklow NR (1984). “A community waterborne gastroenteritis outbreak: evidence for rotavirus as the agent”. American Journal of Public Health 74 (3): 263-5. doi:10.2105/AJPH.74.3.263. PMC 1651463. PMID 6320684. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1651463/. 
  120. ^ Bucardo F, Karlsson B, Nordgren J, etal (2007). “Mutated G4P[8 rotavirus associated with a nationwide outbreak of gastroenteritis in Nicaragua in 2005”]. J. Clin. Microbiol. 45 (3): 990-7. doi:10.1128/JCM.01992-06. PMC 1829148. PMID 17229854. http://jcm.asm.org/cgi/content/full/45/3/990. 
  121. ^ Linhares AC, Pinheiro FP, Freitas RB, Gabbay YB, Shirley JA, Beards GM (1981). “An outbreak of rotavirus diarrhea among a non-immune, isolated South American Indian community”. Am. J. Epidemiol. 113 (6): 703-10. PMID 6263087. 
  122. ^ Hung T, Chen GM, Wang CG, etal (1984). “Waterborne outbreak of rotavirus diarrhea in adults in China caused by a novel rotavirus”. Lancet 1 (8387): 1139-42. doi:10.1016/S0140-6736(84)91391-6. PMID 6144874. 
  123. ^ Fang ZY, Ye Q, Ho MS, etal (1989). “Investigation of an outbreak of adult diarrhea rotavirus in China”. J. Infect. Dis. 160 (6): 948-53. doi:10.1093/infdis/160.6.948. PMID 2555422. 
  124. ^ Kelkar SD, Zade JK (2004). “Group B rotaviruses similar to strain CAL-1, have been circulating in Western India since 1993”. Epidemiol. Infect. 132 (4): 745-9. doi:10.1017/S0950268804002171. PMC 2870156. PMID 15310177. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870156/. 
  125. ^ Ahmed MU, Kobayashi N, Wakuda M, Sanekata T, Taniguchi K, Kader A, Naik TN, Ishino M, Alam MM, Kojima K, Mise K, Sumi A (2004). “Genetic analysis of group B human rotaviruses detected in Bangladesh in 2000 and 2001”. J. Med. Virol. 72 (1): 149-55. doi:10.1002/jmv.10546. PMID 14635024. 
  126. ^ Penaranda ME, Ho MS, Fang ZY, etal (1 October 1989). “Seroepidemiology of adult diarrhea rotavirus in China, 1977 to 1987” (PDF). J. Clin. Microbiol. 27 (10): 2180-3. PMC 266989. PMID 2479654. http://jcm.asm.org/cgi/reprint/27/10/2180. 
  127. ^ Desselberger U, Iturriza-Gomera, Gray JJ (2001). Gastroenteritis viruses. New York: Wiley. pp. 127-128. ISBN 0-471-49663-4 
  128. ^ a b Martella V, Bányai K, Matthijnssens J, Buonavoglia C, Ciarlet M (January 2010). “Zoonotic aspects of rotaviruses”. Veterinary Microbiology 140 (3-4): 246-55. doi:10.1016/j.vetmic.2009.08.028. PMID 19781872. 
  129. ^ Müller H, Johne R (2007). “Rotaviruses: diversity and zoonotic potential—a brief review”. Berl. Munch. Tierarztl. Wochenschr. 120 (3-4): 108-12. PMID 17416132. 
  130. ^ Cook N, Bridger J, Kendall K, Gomara MI, El-Attar L, Gray J (2004). “The zoonotic potential of rotavirus”. J. Infect. 48 (4): 289-302. doi:10.1016/j.jinf.2004.01.018. PMID 15066329. 
  131. ^ Light JS, Hodes HL (1943). “Studies on epidemic diarrhea of the new-born: Isolation of a Filtrable Agent Causing Diarrhea in Calves”. Am. J. Public Health Nations Health 33 (12): 1451-4. doi:10.2105/AJPH.33.12.1451. PMC 1527675. PMID 18015921. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1527675/. 
  132. ^ Mebus CA, Wyatt RG, Sharpee RL, etal (1 August 1976). “Diarrhea in gnotobiotic calves caused by the reovirus-like agent of human infantile gastroenteritis” (PDF). Infect. Immun. 14 (2): 471-4. PMC 420908. PMID 184047. http://iai.asm.org/cgi/reprint/14/2/471. 
  133. ^ Rubenstein D, Milne RG, Buckland R, Tyrrell DA (1971). “The growth of the virus of epidemic diarrhoea of infant mice (EDIM) in organ cultures of intestinal epithelium”. British journal of experimental pathology 52 (4): 442-45. PMC 2072337. PMID 4998842. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2072337/. 
  134. ^ a b Woode GN, Bridger JC, Jones JM, Flewett TH, Davies HA, Davis HA, White GB (1 September 1976). “Morphological and antigenic relationships between viruses (rotaviruses) from acute gastroenteritis in children, calves, piglets, mice, and foals” (PDF). Infect. Immun. 14 (3): 804-10. PMC 420956. PMID 965097. http://iai.asm.org/cgi/reprint/14/3/804. 
  135. ^ a b Flewett TH, Woode GN (1978). “The rotaviruses”. Arch. Virol. 57 (1): 1-23. doi:10.1007/BF01315633. PMID 77663. 
  136. ^ Flewett TH, Bryden AS, Davies H, Woode GN, Bridger JC, Derrick JM (1974). “Relation between viruses from acute gastroenteritis of children and newborn calves”. Lancet 2 (7872): 61-3. doi:10.1016/S0140-6736(74)91631-6. PMID 4137164. 
  137. ^ Matthews RE (1979). “Third report of the International Committee on Taxonomy of Viruses. Classification and nomenclature of viruses”. Intervirology 12 (3-5): 129-296. doi:10.1159/000149081. PMID 43850. 
  138. ^ Beards GM, Brown DW (March 1988). “The antigenic diversity of rotaviruses: significance to epidemiology and vaccine strategies”. European Journal of Epidemiology 4 (1): 1-11. doi:10.1007/BF00152685. PMID 2833405. 
  139. ^ Urasawa T, Urasawa S, Taniguchi K (1981). “Sequential passages of human rotavirus in MA-104 cells”. Microbiol. Immunol. 25 (10): 1025-35. doi:10.1111/j.1348-0421.1981.tb00109.x. PMID 6273696. 
  140. ^ Ward RL, Bernstein DI (January 2009). “Rotarix: a rotavirus vaccine for the world”. Clinical Infectious Diseases 48 (2): 222-8. doi:10.1086/595702. PMID 19072246. http://www.cid.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=19072246. 
  141. ^ “Rotavirus vaccine for the prevention of rotavirus gastroenteritis among children. Recommendations of the Advisory Committee on Immunization Practices (ACIP)”. MMWR Recomm Rep 48 (RR-2): 1-20. (1999). PMID 10219046. 
  142. ^ Kapikian AZ (2001). “A rotavirus vaccine for prevention of severe diarrhoea of infants and young children: development, utilization and withdrawal”. Novartis Found. Symp.. Novartis Foundation Symposia 238: 153-71; discussion 171-9. doi:10.1002/0470846534.ch10. ISBN 9780470846537. PMID 11444025. 
  143. ^ Bines JE (2005). “Rotavirus vaccines and intussusception risk”. Curr. Opin. Gastroenterol. 21 (1): 20-5. PMID 15687880. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0267-1379&volume=21&issue=1&spage=20. 
  144. ^ Bines J (2006). “Intussusception and rotavirus vaccines”. Vaccine 24 (18): 3772-6. doi:10.1016/j.vaccine.2005.07.031. PMID 16099078. 
  145. ^ Dennehy PH (2008). “Rotavirus vaccines: an overview”. Clin. Microbiol. Rev. 21 (1): 198-208. doi:10.1128/CMR.00029-07. PMC 2223838. PMID 18202442. http://cmr.asm.org/cgi/content/full/21/1/198?view=long&pmid=18202442. 
  146. ^ “Meeting of the immunization Strategic Advisory Group of Experts, April 2009—conclusions and recommendations”. Relevé Épidémiologique Hebdomadaire / Section D'hygiène Du Secrétariat De La Société Des Nations = Weekly Epidemiological Record / Health Section of the Secretariat of the League of Nations 84 (23): 220-36. (June 2009). PMID 19499606. http://www.who.int/mediacentre/news/releases/2009/rotavirus_vaccines_20090605/en/index.html. 

[続きの解説]

「ロタウイルス」の続きの解説一覧

英和和英テキスト翻訳>> Weblio翻訳
英語⇒日本語日本語⇒英語
  

辞書ショートカット

カテゴリ一覧

全て

＋ ビジネス

＋ 業界用語

＋ コンピュータ

＋ 電車

＋ 自動車・バイク

＋ 船

＋ 工学

＋ 建築・不動産

＋ 学問

＋ 文化

＋ 生活

＋ ヘルスケア

＋ 趣味

＋ スポーツ

＋ 生物

＋ 食品

＋ 人名

＋ 方言

＋ 辞書・百科事典

すべての辞書の索引

あいうえお
かきくけこ
さしすせそ
たちつてと
なにぬねの
はひふへほ
まみむめも
やゆよ
らりるれろ
わをん
がぎぐげご
ざじずぜぞ
だぢづでど
ばびぶべぼ
ぱぴぷぺぽ
ＡＢＣＤＥ
ＦＧＨＩＪ
ＫＬＭＮＯ
ＰＱＲＳＴ
ＵＶＷＸＹ
Ｚ
１２３４５
６７８９０
記号

Weblioのサービス

「ロタウイルス」の関連用語

1
ロタウイルスの型
ウィキペディア小見出し辞書
78% |||||

2
下痢ウイルス
微生物用語
56% |||||

3
構造タンパク質
ウィキペディア小見出し辞書
54% |||||

4
ロタウイルスNSP3
ウィキペディア小見出し辞書
52% |||||

5
複製
ウィキペディア小見出し辞書
52% |||||

6
牛ロタウイルス病
百科事典
52% |||||

7
ロタウィルス
新語時事用語辞典
52% |||||

8
ウイルス性
ウィキペディア小見出し辞書
38% |||||

9
非構造タンパク質
ウィキペディア小見出し辞書
38% |||||

10
下痢症
国際保健用語
32% |||||

ロタウイルスのお隣キーワード

ロゾーラ

ロゾー郡 (ミネソタ州)

ロタ

ロタ (スペイン)

ロタ (チリ)

ロタウィルス

ロタウイルス

ロタウイルスワクチン

ロタキサン

ロタナ・ジェット

ロタリンギア

ロタンダ

ロターリオ

検索ランキング

   

 英語⇒日本語
日本語⇒英語		    


ロタウイルスのページの著作権
Weblio 辞書 情報提供元は 参加元一覧 にて確認できます。

   
新語時事用語辞典新語時事用語辞典
Copyright © 2024 新語時事用語辞典 All Rights Reserved.
デジタル大辞泉デジタル大辞泉
(C)Shogakukan Inc.
株式会社 小学館
微生物管理機構微生物管理機構
Microbes Control Organization Ver 1.0 (C)1999-2024 Fumiaki Taguchi
ウィキペディアウィキペディア
All text is available under the terms of the GNU Free Documentation License.
この記事は、ウィキペディアのロタウイルス (改訂履歴)の記事を複製、再配布したものにあたり、GNU Free Documentation Licenseというライセンスの下で提供されています。 Weblio辞書に掲載されているウィキペディアの記事も、全てGNU Free Documentation Licenseの元に提供されております。

©2024 GRAS Group, Inc.RSS