ニトロゲナーゼ
(Nitrogenase から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/05/03 07:47 UTC 版)
ニトロゲナーゼ (nitrogenase, EC 1.18.6.1) はリゾビウム (Rhizobium) 属（根粒菌）など窒素固定を行う細菌が持っている酵素。大気中の窒素をアンモニアに変換する反応を触媒する。全体構造は活性中心を有するニトロゲナーゼ二量体およびニトロゲナーゼ二量体に電子を供与するニトロゲナーゼ還元酵素からなる。極めて酸素に弱く、酸素に触れると数分間で不可逆的に失活する。そのため、本酵素を有する生物にはそれぞれ空気中の酸素からニトロゲナーゼを隔離する機構が見られる。
- ^ a b 田宮信雄、八木達彦(1991)コーン・スタンプ生化学 第5版
- ^ a b c d e R. H. Burris (1991) Nitrogenases, J. Biol. Chem., 266 (15), 9339-9342
- ^ J. M. Rivera-Ortiz and R. H. Burris (1975) J. Bacteriol., 123, 537-545
- ^ Rasmussen, L. J., Peters, G. K., and Burris, R. H. (1989) Phykos 28, 64-79
- ^ Yoneyama, T., Yamada, N., Kojima, H., and Yazaki, J. (1984) Plant Cell Physiol., 25, 1561-1565
- ^ L. E. Mortenson, (1964) Biochim. Biophys. Acta, 81, 473-478
- ^ Shah, V. K., Stacey, G., and Brill, W. J. (1983) J. Biol. Chem. 258, 12064-12068
- ^ B. Fodor, G. Rakhely, A. T. Kovacs and K. L. Kovacs (2001) Transposon mutagenesis in purple sulfur photosynthetic bacteria: identification of hypF, encoding a protein capable of processing [NiFe] hydrogenases in alpha, beta, and gamma subdivisions of the proteobacteria, Appl. Environ. Microbiol., 67, 2476-2483
- ^ Young, J. P. W. 1992. Phylogenetic classification of nitrogen-fixing organisms, p. 43-86. In G. Stacey, R. H. Burris, and H. J. Evans (ed.), Biological nitrogen fixation. Chapman and Hall, New York, N.Y.
- ^ a b 桜井英博、柴岡弘郎、清水碩(1997)植物生理学入門、培風館
- ^ a b c Luis M. Rubio and Paul W. Ludden (2005) Maturation of Nitrogenase: a Biochemical Puzzle, J. Bacteriol., 187, 405-414
- ^ Bishop, P. E., D. M. L. Jarlenski, and D. R. Hetherington. 1980. Evidence for an alternative nitrogen fixation system in Azotobacter vinelandii. Proc. Natl. Acad. Sci. USA 77:7342-7346
- ^ Bishop, P. E., R. Premakumar, D. R. Dean, M. R. Jacobson, J. R. Chisnell, T. M. Rizzo, and J. Kopczynski. 1986. Nitrogen fixation by Azotobacter vinelandii strains having deletions in structural genes for nitrogenase. Science 232:92-94
- ^ Davis, R., L. Lehman, R. Petrovich, V. K. Shah, G. P. Roberts, and P. W. Ludden. 1996. Purification and characterization of the alternative nitrogenase from the photosynthetic bacterium Rhodospirillum rubrum. J. Bacteriol. 178, 1445-1450.
- ^ Schneider, K., A. Muller, U. Schramm, and W. Klipp. 1991. Demonstration of a molybdenum- and vanadium-independent nitrogenase in a nifHDKdeletion mutant of Rhodobacter capsulatus. Eur. J. Biochem. 195:653-661.
- ^ Thiel, T. 1993. Characterization of genes for an alternative nitrogenase in the cyanobacterium Anabaena variabilis. J. Bacteriol. 175:6276-6286
- ^ Arnold, W., A. Rump, W. Klipp, U. B. Priefer, and A. Puhler. 1988. Nucleotide sequence of a 24,206-base-pair DNA fragment carrying the entire nitrogen fixation gene cluster of Klebsiella pneumoniae. J. Mol. Biol. 203: 715-738.
- ^ Ribbe, M., D. Gadkari, and O. Meyer. 1997. N2 fixation by Streptomyces thermoautotrophicus involves a molybdenum-dinitrogenase and a manganese-superoxide oxidoreductase that couple N2 reduction to the oxidation of superoxide produced from O2 by a molybdenum-CO dehydrogenase. J. Biol. Chem. 272:26627-26633
- ^ a b Carnahan. J. E.. Mortenson. L. E.. Mower. H. F.. and Castle. J. E. (1960) Biochim. Biophys. Acta 38, 188-189
- ^ a b Carnahan. J. E.. Mortenson. L. E.. Mower. H. F.. and Castle. J. E. (1960) Biochim. Biophys. Acta 44, 520-535
- ^ Mortenson, L. E. (1965) in Non-Heme Iron Proteins: Role in Energy Conversion (San Pietro, A., ed) pp. 243-259, Antioch Press, Yellow Springs OH
- ^ Winter, H. C., and Burris, R. H. (1968) J. Biol. Chem. 243,940-944
- ^ Orme-Johnson, W. H., Hamilton, W. D., Ljones, T., Tso, M.-Y. W., Burris, R. H., Shah, V. K., and Brill, W. J. (1972) Proc. Natl. Acad. Sci. U. S. A. 69, 3142-3145
- ^ Zumft, W. G., and Mortenson, L. E. (1975) Biochim. Biophys. Acta 416, 1-52
- ^ John W Peters and Robert K Szilagyi (2006) Exploring new frontiers of nitrogenase structure and mechanism. Current Opinion in Chemical Biology, 10:101-108
- ^ Dos Santos, P. C., D. R. Dean, Y. Hu, and M. W. Ribbe. 2004. Formation and insertion of the nitrogenase iron-molybdenum cofactor. Chem. Rev. 104:1159-1173
- ^ Imperial, J., V. K. Shah, R. A. Ugalde, P. W. Ludden, and W. J. Brill. 1987. Iron-molybdenum cofactor synthesis in Azotobacter vinelandii Nif- mutants. J. Bacteriol. 169:1784-1786.
- ^ Roberts, G. P., MacNeil, T., MacNeil, D., andBrill, W. J. (1978) J. Bacteriol. 136, 267-279
- ^ Rangaraj, P., C. Ruttimann-Johnson, V. K. Shah, and P. W. Ludden. 2000. Biosynthesis of the iron-molybdenum and iron-vanadium cofactors of the nif- and vnf-encoded nitrogenases, p. 55-79. In E. W. Triplett (ed.), Prokaryotic nitrogen fixation: a model system for analysis of a biochemical process. Horizon Scientific Press, Wymondham, United Kingdom.
- ^ Kennedy, C., and D. Dean. 1992. The nifU, nifS and nifV gene products are required for activity of all three nitrogenases of Azotobacter vinelandii. Mol. Gen. Genet. 231:494-498.
- ^ Ludden, P. W., and Burns, R. H. (1976) Science 194,424-426
- ^ Ludden, P. W., and Roberts, G. P. (1989) Curr. Top. Cell. Regul. 30,23-56
- ^ Postgate, J. R. (1982) The Fundamentals of Nitrogen Fixation, Cambridge University Press, London
- ^ Bergmann, B., Gallon, J, R., Rai, A. N., and Stal, L. J., (1997) N2 fixation by non-heterocystous cyanobacteria. FEMS. Microbiol. Rev., 19, 139-185
[続きの解説]
「ニトロゲナーゼ」の続きの解説一覧
- Nitrogenaseのページへのリンク
