WNTとは? わかりやすく解説

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WNT

出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2010/05/03 02:32 UTC 版)

WNT



Wntシグナル経路

(WNT から転送)

出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2024/02/05 19:57 UTC 版)

Wntシグナル経路(ウィント-シグナルけいろ、: Wnt signaling pathway)は、細胞表面受容体を介して細胞内へシグナルを伝達するタンパク質によって開始されるシグナル伝達経路の1つである。Wntという名称は、winglessint-1という2つの遺伝子の名称に由来する「かばん語」である[1]。Wntシグナル経路は、近接する細胞間のコミュニケーション(傍分泌)または細胞自身に対するコミュニケーション(自己分泌)のいずれかを利用する。この経路は動物で進化的に高度に保存されており、ショウジョウバエからヒトまで類似した経路が存在する[2][3]


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