マクロファージ炎症性タンパク質
(Macrophage Inflammatory Protein から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/12/31 10:12 UTC 版)
マクロファージ炎症性タンパク質（マクロファージえんしょうせいタンパクしつ、英: macrophage inflammatory protein、略称: MIP）は、ケモカインと呼ばれる走化性サイトカインのファミリーの1つである。ヒトではMIP-1α、MIP-1βと呼ばれる2つの主要なメンバーが存在し、現在では公式にはそれぞれCCL3、CCL4と呼ばれている[3]。古い文献では、ヒトCCL3に関してはLD78α、AT 464.1、GOS19-1、ヒトCCL4に関してはAT 744、Act-2、LAG-1、HC21、G-26などの名称が用いられている[4]。その他のMIPとして、MIP-2、MIP-3、MIP-5が存在する。
- ^ “Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants”. The Journal of Biological Chemistry 274 (23): 16077–84. (June 1999). doi:10.1074/jbc.274.23.16077. PMID 10347159.
- ^ “High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR”. Science 263 (5154): 1762–7. (March 1994). Bibcode: 1994Sci...263.1762L. doi:10.1126/science.8134838. PMID 8134838.
- ^ a b c d “Chemokines: a new classification system and their role in immunity”. Immunity 12 (2): 121–7. (February 2000). doi:10.1016/S1074-7613(00)80165-X. PMID 10714678.
- ^ a b c d e “Macrophage inflammatory protein-1”. Cytokine & Growth Factor Reviews 13 (6): 455–81. (December 2002). doi:10.1016/S1359-6101(02)00045-X. PMID 12401480.
- ^ “Resolution of the two components of macrophage inflammatory protein 1, and cloning and characterization of one of those components, macrophage inflammatory protein 1 beta”. The Journal of Experimental Medicine 168 (6): 2251–9. (December 1988). doi:10.1084/jem.168.6.2251. PMC 2189160. PMID 3058856.
- ^ a b “Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme”. The EMBO Journal 29 (23): 3952–66. (December 2010). doi:10.1038/emboj.2010.256. PMC 3020635. PMID 20959807.
- ^ “Examination of the function of RANTES, MIP-1alpha, and MIP-1beta following interaction with heparin-like glycosaminoglycans”. The Journal of Biological Chemistry 275 (16): 11721–7. (April 2000). doi:10.1074/jbc.275.16.11721. PMID 10766793.
- ^ a b c Murphy, Kenneth; Weaver, Casey (2017). Janeway's Immunobiology. New York: Garland Science, Taylor & Francis Group, LLC. pp. 456. ISBN 978-0-8153-4505-3
- ^ “Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q”. Nucleic Acids Research 18 (11): 3261–70. (June 1990). doi:10.1093/nar/18.11.3261. PMC 330932. PMID 1972563.
- ^ a b “Macrophage inflammatory protein-1”. The International Journal of Biochemistry & Cell Biology 36 (10): 1882–6. (October 2004). doi:10.1016/j.biocel.2003.10.019. PMID 15203102.
- ^ “Macrophage inflammatory protein-2 as mediator of inflammation in acute liver injury”. World Journal of Gastroenterology 23 (17): 3043–3052. (May 2017). doi:10.3748/wjg.v23.i17.3043. PMC 5423041. PMID 28533661.
- ^ “Identification of inflammatory mediators associated with metastasis of oral squamous cell carcinoma in experimental and clinical studies: systematic review”. Clinical & Experimental Metastasis 36 (6): 481–492. (December 2019). doi:10.1007/s10585-019-09994-x. PMID 31559586.
- ^ a b “Dendritic cell biology and regulation of dendritic cell trafficking by chemokines”. Springer Seminars in Immunopathology 22 (4): 345–69. (December 2000). doi:10.1007/s002810000053. PMID 11155441.
- ^ “The CCR6-CCL20 axis in humoral immunity and T-B cell immunobiology”. Immunobiology 224 (3): 449–454. (May 2019). doi:10.1016/j.imbio.2019.01.005. PMID 30772094.
- ^ “CCL19 and CCR7 Expression, Signaling Pathways, and Adjuvant Functions in Viral Infection and Prevention”. Frontiers in Cell and Developmental Biology 7: 212. (2019-10-01). doi:10.3389/fcell.2019.00212. PMC 6781769. PMID 31632965.
- ^ “CC-chemokine CCL15 expression and possible implications for the pathogenesis of IgE-related severe asthma”. Mediators of Inflammation 2012: 475253. (2012). doi:10.1155/2012/475253. PMC 3508751. PMID 23258953.
[続きの解説]
「マクロファージ炎症性タンパク質」の続きの解説一覧
- 1 マクロファージ炎症性タンパク質とは
- 2 マクロファージ炎症性タンパク質の概要
- 3 MIP-3
- マクロファージ炎症性タンパク質のページへのリンク
