酸化ストレス
(oxidative stress から転送)
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/05/05 04:48 UTC 版)
酸化ストレス（さんかストレス、英: Oxidative stress）とは、活性酸素が産生され障害作用を発現する生体作用と、生体システムが活性酸素を直接解毒したり、生じた障害を修復したりする生体作用との間で、均衡が崩れた状態のことである。生体組織の通常の酸化還元状態が乱されると、過酸化物やフリーラジカルが産生され、タンパク質、脂質そしてDNAが障害されることで、様々な細胞内器官が障害を受ける。
- ^ “Oxidative Stress and ADHD: A Meta-Analysis”. J Atten Disord 19 (11): 915–24. (November 2015). doi:10.1177/1087054713510354. PMC 5293138. PMID 24232168.
- ^ “Atherosclerosis and oxidative stress”. Histol. Histopathol. 23 (3): 381–90. (March 2008). doi:10.14670/HH-23.381. PMID 18072094.
- ^ “Role of oxidative stress in Parkinson's disease”. Exp Neurobiol 22 (1): 11–7. (March 2013). doi:10.5607/en.2013.22.1.11. PMC 3620453. PMID 23585717.
- ^ “Increased oxidative stress and impaired antioxidant response in Lafora disease”. Mol. Neurobiol. 51 (3): 932–46. (2015). doi:10.1007/s12035-014-8747-0. hdl:10261/123869. PMID 24838580.
- ^ “Oxidative stress and heart failure”. Mol. Cell. Biochem. 147 (1–2): 77–81. (1995). doi:10.1007/BF00944786. PMID 7494558.
- ^ “Oxidative stress mediates cardiac infarction aggravation induced by intermittent hypoxia”. Fundam Clin Pharmacol 27 (3): 252–61. (June 2013). doi:10.1111/j.1472-8206.2011.01015.x. PMID 22145601.
- ^ “N-acetyl cysteine restores brain glutathione loss in combined 2-cyclohexene-1-one and D-amphetamine-treated rats: relevance to schizophrenia and bipolar disorder”. Neurosci. Lett. (3): 149–53. (July 2011). doi:10.1016/j.neulet.2011.05.027. PMID 21621586.
- ^ “Free radicals and antioxidants in normal physiological functions and human disease”. Int. J. Biochem. Cell Biol. 39 (1): 44–84. (2007pmid=16978905). doi:10.1016/j.biocel.2006.07.001.
- ^ “Red blood cells, platelets and polymorphonuclear neutrophils of patients with sickle cell disease exhibit oxidative stress that can be ameliorated by antioxidants”. Br. J. Haematol. 132 (1): 108–13. (January 2006). doi:10.1111/j.1365-2141.2005.05834.x. PMID 16371026.
- ^ de Diego-Otero Y, Romero-Zerbo Y, el Bekay R, Decara J, Sanchez L, Rodriguez-de Fonseca F, del Arco-Herrera I. (March 2009). “Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency.”. Neuropsychopharmacology 34 (4): 1011–26. doi:10.1038/npp.2008.152. PMID 18843266.
- ^ “Oxidative stress in lichen planus”. Acta Dermatovenerol Alp Pannonica Adriat 19 (1): 3–11. (2010). PMID 20372767.
- ^ “Oxidative stress in the blood of patients with active localized vitiligo”. Acta Dermatovenerol Alp Pannonica Adriat 17 (1): 12–6. (March 2008). PMID 18454264.
- ^ “Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism”. Am. J. Clin. Nutr. 80 (6): 1611–7. (December 2004). doi:10.1093/ajcn/80.6.1611. PMID 15585776.
- ^ “Oxidative stress and antioxidant parameters in patients with major depressive disorder compared to healthy controls before and after antidepressant treatment: results from a meta-analysis”. J Clin Psychiatry 76 (12): 1658–67. (December 2015). doi:10.4088/JCP.14r09179. PMID 26579881.
- ^ “Oxidative stress levels are raised in chronic fatigue syndrome and are associated with clinical symptoms”. Free Radic. Biol. Med. 39 (5): 584–9. (September 2005). doi:10.1016/j.freeradbiomed.2005.04.020. PMID 16085177.
- ^ “Plasma antioxidant capacity is reduced in Asperger syndrome”. J Psychiatr Res 46 (3): 394–401. (March 2012). doi:10.1016/j.jpsychires.2011.10.004. PMID 22225920.
- ^ “How neutrophils kill microbes”. Annu. Rev. Immunol. 23: 197–223. (2005). doi:10.1146/annurev.immunol.23.021704.115653. PMC 2092448. PMID 15771570.
- ^ “Stress-response hormesis and aging: "that which does not kill us makes us stronger"”. Cell Metab. 7 (3): 200–3. (March 2008). doi:10.1016/j.cmet.2008.01.001. PMID 18316025.
- ^ “Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple”. Free Radic. Biol. Med. 30 (11): 1191–212. (2001). doi:10.1016/S0891-5849(01)00480-4. PMID 11368918.
- ^ “Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli”. Cell Prolif. 24 (2): 203–14. (1991). doi:10.1111/j.1365-2184.1991.tb01150.x. PMID 2009322.
- ^ “Metals, toxicity and oxidative stress”. Curr. Med. Chem. 12 (10): 1161–208. (2005). doi:10.2174/0929867053764635. PMID 15892631.
- ^ 酸化ストレスを感知する仕組みを解明～何重にも張り巡らされたストレス感知のための巧妙な仕組み～東北大学プレスリリース（2019年7月17日）2020年1月13日閲覧
[続きの解説]
「酸化ストレス」の続きの解説一覧
- 1 酸化ストレスとは
- 2 酸化ストレスの概要
- 3 外部リンク
「oxidative stress」の例文・使い方・用例・文例
- oxidative stressのページへのリンク
