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EXO1
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/12/10 02:26 UTC 版)
EXO1（exonuclease 1）は、ヒトではEXO1遺伝子にコードされる酵素である[5][6][7]。
- ^ a b c GRCh38: Ensembl release 89: ENSG00000174371 - Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039748 - Ensembl, May 2017
- ^ Human PubMed Reference:
- ^ Mouse PubMed Reference:
- ^ “Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1”. Nucleic Acids Res 26 (16): 3762–8. (September 1998). doi:10.1093/nar/26.16.3762. PMC 147753. PMID 9685493.
- ^ a b “Human exonuclease I interacts with the mismatch repair protein hMSH2”. Cancer Res 58 (20): 4537–42. (November 1998). PMID 9788596.
- ^ a b “Entrez Gene: EXO1 exonuclease 1”. 2022年12月24日閲覧。
- ^ “Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance.”. J. Biol. Chem. 274 (25): 17893–900. (June 1999). doi:10.1074/jbc.274.25.17893. PMID 10364235.
- ^ a b c “Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae”. Mol. Biol. Cell 11 (7): 2221–33. (2000). doi:10.1091/mbc.11.7.2221. PMC 14915. PMID 10888664.
- ^ a b “Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility”. Genes Dev. 17 (5): 603–14. (2003). doi:10.1101/gad.1060603. PMC 196005. PMID 12629043.
- ^ “Temporally and biochemically distinct activities of Exo1 during meiosis: double-strand break resection and resolution of double Holliday junctions”. Mol. Cell 40 (6): 1001–15. (2010). doi:10.1016/j.molcel.2010.11.032. PMC 3061447. PMID 21172664.
- ^ “Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase”. Cell 149 (2): 334–47. (2012). doi:10.1016/j.cell.2012.03.023. PMC 3377385. PMID 22500800.
- ^ “Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice”. Nucleic Acids Res 50 (14): 8093–8106. (2022). doi:10.1093/nar/gkac616. PMC 9371890. PMID 35849338.
- ^ Rasmussen, L J; Rasmussen M; Lee B; Rasmussen A K; Wilson D M; Nielsen F C; Bisgaard H C (June 2000). “Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis”. Mutat. Res. 460 (1): 41–52. doi:10.1016/S0921-8777(00)00012-4. ISSN 0027-5107. PMID 10856833.
- ^ a b Schmutte, C; Sadoff M M; Shim K S; Acharya S; Fishel R (August 2001). “The interaction of DNA mismatch repair proteins with human exonuclease I”. J. Biol. Chem. 276 (35): 33011–8. doi:10.1074/jbc.M102670200. ISSN 0021-9258. PMID 11427529.
[続きの解説]
- EXO1のページへのリンク
