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ERCC4

出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2023/02/04 13:45 UTC 版)

ERCC4（excision repair cross-complementation group 4）もしくはXPF（xeroderma pigmentosum complementation group F）は、ヒトではERCC4遺伝子にコードされるタンパク質である。ERCC4はERCC1とともにERCC1-XPF複合体を形成し、DNA修復やDNA組換えに関与する^[5]^[6]。

出典

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175595 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022545 - Ensembl, May 2017
^ Human PubMed Reference:
^ Mouse PubMed Reference:
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^ “The Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF Complex.”. J Biol Chem 290 (33): 20541–20555. (August 2015). doi:10.1074/jbc.M114.635169. ISSN 1083-351X. PMC 4536458. PMID 26085086.
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