Bub3とは? わかりやすく解説

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BUB3

出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2023/07/16 08:39 UTC 版)

BUB3(budding uninhibited by benzimidazoles 3)は、ヒトではBUB3遺伝子にコードされるタンパク質である[5][6]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000154473 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000066979 - Ensembl, May 2017
  3. ^ Human PubMed Reference:
  4. ^ Mouse PubMed Reference:
  5. ^ a b c “The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase”. The Journal of Cell Biology 142 (1): 1–11. (July 1998). doi:10.1083/jcb.142.1.1. PMC 2133037. PMID 9660858. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133037/. 
  6. ^ Entrez Gene: BUB3 BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)”. 2023年6月25日閲覧。
  7. ^ a b c Morgan, David O (2007). The cell cycle: principles of control. London: Published by New Science Press in association with Oxford University Press. ISBN 978-0-87893-508-6 
  8. ^ a b c “Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis”. Genes & Development 14 (18): 2277–82. (September 2000). doi:10.1101/gad.827500. PMC 316933. PMID 10995385. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316933/. 
  9. ^ “Two different mitotic checkpoint inhibitors of the anaphase-promoting complex/cyclosome antagonize the action of the activator Cdc20”. Proceedings of the National Academy of Sciences of the United States of America 105 (27): 9181–5. (July 2008). Bibcode2008PNAS..105.9181E. doi:10.1073/pnas.0804069105. PMC 2453698. PMID 18591651. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453698/. 
  10. ^ “Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1”. Molecular Cell 2 (2): 163–71. (August 1998). doi:10.1016/S1097-2765(00)80126-4. PMID 9734353. 
  11. ^ a b c “Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores”. The EMBO Journal 20 (23): 6648–59. (December 2001). doi:10.1093/emboj/20.23.6648. PMC 125326. PMID 11726501. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC125326/. 
  12. ^ Jin, Dong-Yan, ed (November 2009). “Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosis”. PLOS ONE 4 (11): e7701. Bibcode2009PLoSO...4.7701L. doi:10.1371/journal.pone.0007701. PMC 2765619. PMID 19888327. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765619/. 
  13. ^ “Regulation of APC-Cdc20 by the spindle checkpoint”. Current Opinion in Cell Biology 14 (6): 706–14. (December 2002). doi:10.1016/S0955-0674(02)00382-4. PMID 12473343. 
  14. ^ Khanin, Raya, ed (August 2009). “Reverse engineering of the spindle assembly checkpoint”. PLOS ONE 4 (8): e6495. Bibcode2009PLoSO...4.6495D. doi:10.1371/journal.pone.0006495. PMC 2714964. PMID 19652707. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714964/. 
  15. ^ “Crystal structure of the spindle assembly checkpoint protein Bub3”. Journal of Molecular Biology 344 (4): 885–92. (December 2004). doi:10.1016/j.jmb.2004.09.094. PMID 15544799. 
  16. ^ “Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2”. The Journal of Cell Biology 154 (5): 925–36. (September 2001). doi:10.1083/jcb.200102093. PMC 2196190. PMID 11535616. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2196190/. 
  17. ^ “The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1”. Biochemical and Biophysical Research Communications 298 (5): 720–30. (November 2002). doi:10.1016/S0006-291X(02)02522-6. PMID 12419313. 
  18. ^ a b “WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase”. FEBS Letters 575 (1–3): 23–9. (September 2004). doi:10.1016/j.febslet.2004.07.089. PMID 15388328. 
  19. ^ “Kinetochore-microtubule interactions "in check" by Bub1, Bub3 and BubR1: The dual task of attaching and signalling”. Cell Cycle 7 (12): 1763–8. (June 2008). doi:10.4161/cc.7.12.6180. PMID 18594200. 


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