プロリンラセマーゼとは - わかりやすく解説 Weblio辞書

ウィキペディア

索引トップ用語の索引ランキングカテゴリー

プロリンラセマーゼ

出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2013/03/02 12:04 UTC 版)

プロリンラセマーゼ(Proline racemase、EC 5.1.1.4)は、以下の化学反応を触媒する酵素である。

出典

^ Fisher LM, Albery WJ, Knowles JR (May 1986). “Energetics of proline racemase: racemization of unlabeled proline in the unsaturated, saturated, and oversaturated regimes”. Biochemistry 25 (9): 2529-37. doi:10.1021/bi00357a037. PMID 3755058.
^ Reina-San-Martin B, Degrave W, Rougeot C, Cosson A, Chamond N, Cordeiro-Da-Silva A, Arala-Chaves M, Coutinho A, Minoprio P (August 2000). “A B-cell mitogen from a pathogenic trypanosome is a eukaryotic proline racemase”. Nat. Med. 6 (8): 890-7. doi:10.1038/78651. PMID 10932226.
^ Chamond N, Goytia M, Coatnoan N, Barale JC, Cosson A, Degrave WM, Minoprio P (October 2005). “Trypanosoma cruzi proline racemases are involved in parasite differentiation and infectivity”. Mol. Microbiol. 58 (1): 46-60. doi:10.1111/j.1365-2958.2005.04808.x. PMID 16164548.
^ Goytia M, Chamond N, Cosson A, Coatnoan N, Hermant D, Berneman A, Minoprio P (2007). “Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens”. PLoS ONE 2 (9): e885. doi:10.1371/journal.pone.0000885. PMC 1964878. PMID 17849014.
^ Chamond N, Cosson A, Coatnoan N, Minoprio P (June 2009). “Proline racemases are conserved mitogens: characterization of a Trypanosoma vivax proline racemase”. Mol. Biochem. Parasitol. 165 (2): 170-9. doi:10.1016/j.molbiopara.2009.02.002. PMID 19428664.
^ Cardinale GJ, Abeles RH (November 1968). “Purification and mechanism of action of proline racemase”. Biochemistry 7 (11): 3970-8. doi:10.1021/bi00851a026. PMID 5722267.
^ PDB 1W61 and PDB 1W62; Buschiazzo A, Goytia M, Schaeffer F, Degrave W, Shepard W, Gregoire C, Chamond N, Cosson A, Berneman A, Coatnoan N, Alzari PM, Minoprio P (February 2006). “Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase”. Proc. Natl. Acad. Sci. U.S.A. 103 (6): 1705-10. doi:10.1073/pnas.0509010103. PMC 1413642. PMID 16446443.
^ Albery WJ, Knowled JR (May 1986). “Energetics and mechanism of proline racemase”. Biochemistry 25 (9): 2572-7. doi:10.1021/bi00357a043. PMID 3718964.