ヒトコロナウイルスOC43とは? わかりやすく解説

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ヒトコロナウイルスOC43

出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2021/08/15 09:10 UTC 版)

ヒトコロナウイルスOC43(HCoV-OC43, Human coronavirus OC43)は、ヒトに感染するコロナウイルス[1]。ベータコロナウイルス属(第2群コロナウイルス)のエンベコウイルス亜属、ベータコロナウイルス1というウイルス種に含まれる[2]ライノウイルスヒトコロナウイルス229EHKU1NL63などと同様に、ヒトに風邪を引き起こす[3][4]


  1. ^ Lim, Yvonne Xinyi; Ng, Yan Ling; Tam, James P.; Liu, Ding Xiang (2016-07-25). “Human Coronaviruses: A Review of Virus–Host Interactions”. Diseases 4 (3): 26. doi:10.3390/diseases4030026. ISSN 2079-9721. PMC 5456285. PMID 28933406. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456285/. "See Table 1." 
  2. ^ Taxonomy browser (Betacoronavirus 1)”. www.ncbi.nlm.nih.gov. 2020年2月29日閲覧。
  3. ^ Lau, Susanna K. P.; Lee, Paul; Tsang, Alan K. L.; Yip, Cyril C. Y.; Tse, Herman; Lee, Rodney A.; So, Lok-Yee; Lau, Y.-L. et al. (2011). “Molecular Epidemiology of Human Coronavirus OC43 Reveals Evolution of Different Genotypes over Time and Recent Emergence of a Novel Genotype due to Natural Recombination”. Journal of Virology 85 (21): 11325–37. doi:10.1128/JVI.05512-11. PMC 3194943. PMID 21849456. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194943/. 
  4. ^ E. R. Gaunt,1 A. Hardie,2 E. C. J. Claas,3 P. Simmonds,1 and K. E. Templeton. Epidemiology and Clinical Presentations of the Four Human Coronaviruses 229E, HKU1, NL63, and OC43 Detected over 3 Years Using a Novel Multiplex Real-Time PCR Method down-pointing small open triangle. J Clin Microbiol. 2010 August; 48(8): 2940–2947.
  5. ^ Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). “Coronavirus Genomics and Bioinformatics Analysis”. Viruses 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185738/. "In all members of Betacoronavirus subgroup A, a haemagglutinin esterase (HE) gene, which encodes a glycoprotein with neuraminate O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1)." 
  6. ^ Li, Fang (2016-09-29). “Structure, Function, and Evolution of Coronavirus Spike Proteins”. Annual Review of Virology 3 (1): 237–261. doi:10.1146/annurev-virology-110615-042301. ISSN 2327-056X. PMC 5457962. PMID 27578435. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457962/. "BCoV S1-NTD does not recognize galactose as galectins do. Instead, it recognizes 5-N-acetyl-9-O-acetylneuraminic acid (Neu5,9Ac2) (30, 43). The same sugar receptor is also recognized by human coronavirus OC43 (43, 99). OC43 and BCoV are closely related genetically, and OC43 might have resulted from zoonotic spillover of BCoV (100, 101)." 
  7. ^ Vijgen, Leen; Keyaerts, Els; Lemey, Philippe; Maes, Piet; Van Reeth, Kristien; Nauwynck, Hans; Pensaert, Maurice; Van Ranst, Marc (2006). “Evolutionary History of the Closely Related Group 2 Coronaviruses: Porcine Hemagglutinating Encephalomyelitis Virus, Bovine Coronavirus, and Human Coronavirus OC43”. Journal of Virology 80 (14): 7270–7274. doi:10.1128/JVI.02675-05. PMC 1489060. PMID 16809333. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489060/. 
  8. ^ ヒトに感染するコロナウイルス
  9. ^ Severance EG, Bossis I, Dickerson FB, et al. (2008). “Development of a nucleocapsid-based human coronavirus immunoassay and estimates of individuals exposed to coronavirus in a U.S. metropolitan population”. Clin Vaccine Immunol. doi:10.1128/CVI.00124-08. PMID 18945884. 
  10. ^ Weimin Zhou 1, Wen Wang, Huijuan Wang, Roujian Lu, Wenjie Tan (2013). “First infection by all four non-severe acute respiratory syndrome human coronaviruses takes place during childhood”. BMC Infect Dis. 13: 433. doi:10.1186/1471-2334-13-433. PMID 3848659. 
  11. ^ a b K. A. Callow et al. (1990). “The time course of the immune response to experimental coronavirus infection of man.”. Epidemiol Infect. 105 (2): 435–446. doi:10.1017/s0950268800048019. PMID 2170159. 
  12. ^ a b Arthur WD Edridge, et al. (2020). “Coronavirus protective immunity is short-lasting”. MedRxic. doi:10.1101/2020.05.11.20086439. 
  13. ^ ヒトコロナウイルス(HCoV)感染症の季節性について―病原微生物検出情報(2015~2019年)報告例から(国立感染症研究所)
  14. ^ Wevers, Brigitte A.; Van Der Hoek, Lia (2009). “Recently Discovered Human Coronaviruses”. Clinics in Laboratory Medicine 29 (4): 715–24. doi:10.1016/j.cll.2009.07.007. PMID 19892230. 
  15. ^ Mahony, James B. (2007). “Coronaviruses”. In Murray, Patrick R.; Baron, Ellen Jo; Jorgensen, James H. et al.. Manual of Clinical Microbiology (9th ed.). Washington D.C.: ASM Press. pp. 1414–23. ISBN 978-1-55581-371-0 
  16. ^ Pyrc, K.; Berkhout, B.; Van Der Hoek, L. (2007). “Antiviral Strategies Against Human Coronaviruses”. Infectious Disorders Drug Targets 7 (1): 59–66. doi:10.2174/187152607780090757. PMID 17346212. 
  17. ^ 2015年山形市近郊で流行したコロナウイルスOC43 感染症(日本外来小児科学会 2015 仙台)
  18. ^ Ana B Gorini da Veiga et al. (28 July 2020). “More than just a common cold: Endemic coronaviruses OC43, HKU1, NL63, and 229E associated with severe acute respiratory infection and fatality cases among healthy adults”. J Med Virol. doi:10.1002/jmv.26362. PMID 32720706. 
  19. ^ Hélène Jacomy, Pierre J Talbot (2003 Oct 10). “Vacuolating encephalitis in mice infected by human coronavirus OC43”. Virology. 315 (1): 20-33. doi:10.1016/s0042-6822(03)00323-4. 
  20. ^ Morfopoulou, Sofia; Brown, Julianne R.; Davies, E. Graham; Anderson, Glenn; Virasami, Alex; Qasim, Waseem; Chong, Wui K.; Hubank, Michael et al. (2016). “Human Coronavirus OC43 Associated with Fatal Encephalitis”. New England Journal of Medicine 375 (5): 497–498. doi:10.1056/NEJMc1509458. ISSN 0028-4793. 
  21. ^ N Arbour et al. (2000 Oct). “Neuroinvasion by human respiratory coronaviruses”. J Virol. 74 (19): 8913-21. doi:10.1128/jvi.74.19.8913-8921.2000. 
  22. ^ R S Murray et al. (1992 May). “Detection of coronavirus RNA and antigen in multiple sclerosis brain”. Ann Neurol. 31 (5): 525-33. doi:10.1002/ana.410310511. 
  23. ^ A Cristallo et al. (1997 Apr). “Human coronavirus polyadenylated RNA sequences in cerebrospinal fluid from multiple sclerosis patients”. New Microbiol. 20 (2): 105-14. PMID 9208420. 
  24. ^ F Lahrtz et al. (1998 May 1). “Chemokines and chemotaxis of leukocytes in infectious meningitis”. J Neuroimmunol. 85 (1): 33-43.. doi:10.1016/s0165-5728(97)00267-1. PMID 9626995. 
  25. ^ Vijgen, Leen; Keyaerts, Els; Lemey, Philippe; Maes, Piet; Van Reeth, Kristien; Nauwynck, Hans; Pensaert, Maurice; Van Ranst, Marc (2006). “Evolutionary History of the Closely Related Group 2 Coronaviruses: Porcine Hemagglutinating Encephalomyelitis Virus, Bovine Coronavirus, and Human Coronavirus OC43”. Journal of Virology 80 (14): 7270–7274. doi:10.1128/JVI.02675-05. PMC 1489060. PMID 16809333. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489060/. 
  26. ^ a b Our Coronavirus Predicament Isn’t All That New(The Russian flu pandemic of 1889 might have actually been caused by a foe that has become all too familiar.) - Bloomberg Opinion(2020年5月16日)
  27. ^ “Transmissibility and geographic spread of the 1889 influenza pandemic”. PNAS 107 (19): 8778–8781. (11 May 2010). Bibcode2010PNAS..107.8778V. doi:10.1073/pnas.1000886107. PMC 2889325. PMID 20421481. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889325/. 
  28. ^ “Influenza A virus recycling revisited”. Bulletin of the World Health Organization (Geneva: World Health Organization) 77 (10): 820–828. (1999). PMC 2557748. PMID 10593030. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557748/. 
  29. ^ A brief history of the coronavirus family – including one pandemic we might have missed - The Conversation
  30. ^ a b c Vijgen, Leen; Keyaerts, Els; Moës, Elien; Thoelen, Inge; Wollants, Elke; Lemey, Philippe; Vandamme, Anne-Mieke; Van Ranst, Marc (2005). “Complete Genomic Sequence of Human Coronavirus OC43: Molecular Clock Analysis Suggests a Relatively Recent Zoonotic Coronavirus Transmission Event”. Journal of Virology 79 (3): 1595–1604. doi:10.1128/JVI.79.3.1595-1604.2005. PMC 544107. PMID 15650185. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544107/. 
  31. ^ Overraskende opdagelse: Coronavirus har tidligere lagt verden ned
  32. ^ PANDÉMIE DE GRIPPE RUSSE : UNE COVID DU XIXE SIÈCLE ?
  33. ^ “Past Influenza pandemics and their effect in Malta”. Malta Medical Journal 17 (3): 16–19. (2005). https://www.um.edu.mt/library/oar/handle/123456789/651 2020年3月25日閲覧. "1889-90 pandemic – The Asiatic Flu [...] by the end of March 1890. The case fatality rate approximated 4.0% [Table 1]. A resurgence of the infection became apparent in January-May 1892 with a total of 2017 reported cases and 66 deaths [case fatality rate 3.3%]" 
  34. ^ The Pandemic’s Future — and Ours


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