クロストリジウム・ディフィシル腸炎
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2024/02/25 13:38 UTC 版)
クロストリジウム・ディフィシル腸炎（クロストリジウム・ディフィシルちょうえん、英語: Clostridium difficile colitis）（CD腸炎）または偽膜性大腸炎（ぎまくせいだいちょうえん、英語: Pseudomembranous colitis）は、芽胞産生性偏性嫌気性細菌であるクロストリディオイデス・ディフィシル（Clostridioides difficile）の異常増殖の結果として生じる大腸炎である[1][2]。クロストリジウム・ディフィシル関連下痢症 (C. difficile associated diarrhea, CDAD) と呼ばれる炎症性下痢症の原因となる[3]。潜在性のC. difficile 感染症 (CDI) は、しばしばインフルエンザ様症状と共通点があり、炎症性腸疾患患者の場合には腸炎の再燃を思わせる[4]。C. difficile が産生する毒素は腹痛を伴う巨大結腸症（中毒性巨大結腸症）や下痢を引き起こし、重篤となる場合もある[3]。
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