ステリルスルファターゼ
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/10/14 23:10 UTC 版)
ステリルスルファターゼ(Steryl-sulfatase)またはステロイドスルファターゼ(Steroid sulfatase)は、ステロイドの代謝に関連するスルファターゼ酵素である。STS遺伝子によりコードされる[1]。かつては、アリルスルファターゼC(arylsulfatase C)とも呼ばれた。系統名は、ステリル硫酸 スルホヒドロラーゼ(steryl-sulfate sulfohydrolase)である[2][3][4]。
- ^ a b “Entrez Gene: STS steroid sulfatase (microsomal), arylsulfatase C, isozyme S”. 2022年10月14日閲覧。
- ^ “The steroid sulphatase of Patella vulgata”. Biochimica et Biophysica Acta 15 (2): 300-1. (October 1954). doi:10.1016/0006-3002(54)90078-5. PMC 1274509. PMID 13208702.
- ^ “The synthesis and hydrolysis of sulfate esters”. Advances in Enzymology and Related Areas of Molecular Biology. Advances in Enzymology - and Related Areas of Molecular Biology. 22. (1960). 205-35. doi:10.1002/9780470122679.ch5. ISBN 9780470122679. PMID 13744184
- ^ “The enzymic hydrolysis of steroid conjugates. I. Sulphatase and β-glucuronidase activity of molluscan extracts”. The Biochemical Journal 63 (4): 705-10. (August 1956). doi:10.1042/bj0630705. PMC 1216242. PMID 13355874.
- ^ a b “The Regulation of Steroid Action by Sulfation and Desulfation”. Endocrine Reviews 36 (5): 526-63. (October 2015). doi:10.1210/er.2015-1036. PMC 4591525. PMID 26213785.
- ^ “The Important Roles of Steroid Sulfatase and Sulfotransferases in Gynecological Diseases”. Frontiers in Pharmacology 7: 30. (2016). doi:10.3389/fphar.2016.00030. PMC 4757672. PMID 26924986.
- ^ “Systemic distribution of steroid sulfatase and estrogen sulfotransferase in human adult and fetal tissues”. The Journal of Clinical Endocrinology and Metabolism 87 (12): 5760-8. (December 2002). doi:10.1210/jc.2002-020670. PMID 12466383.
- ^ “Characterization of point mutations in patients with X-linked ichthyosis. Effects on the structure and function of the steroid sulfatase protein”. The Journal of Biological Chemistry 272 (33): 20756-63. (August 1997). doi:10.1074/jbc.272.33.20756. PMID 9252398.
- ^ “Mutations in X-linked ichthyosis disrupt the active site structure of estrone/DHEA sulfatase”. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1739 (1): 1-4. (December 2004). doi:10.1016/j.bbadis.2004.09.003. PMID 15607112.
- ^ “Medical and neurobehavioural phenotypes in carriers of X-linked ichthyosis-associated genetic deletions in the UK Biobank”. Journal of Medical Genetics 57 (10): 692-698. (Mar 2020). doi:10.1136/jmedgenet-2019-106676. PMC 7525778. PMID 32139392.
- ^ a b “SULFATION PATHWAYS: Steroid sulphatase inhibition via aryl sulphamates: clinical progress, mechanism and future prospects”. Journal of Molecular Endocrinology 61 (2): T233-T252. (August 2018). doi:10.1530/JME-18-0045. PMID 29618488.
- ^ “Estrogen O-sulfamates and their analogues: Clinical steroid sulfatase inhibitors with broad potential”. The Journal of Steroid Biochemistry and Molecular Biology 153: 160-9. (September 2015). doi:10.1016/j.jsbmb.2015.03.012. PMID 25843211.
- ^ “Inhibition of steroid sulfatase activity by danazol”. Acta Obstetricia et Gynecologica Scandinavica Supplement 123: 107-11. (1984). doi:10.3109/00016348409156994. PMID 6238495.
- ^ “Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health”. Journal of Medicinal Chemistry 58 (19): 7634-58. (October 2015). doi:10.1021/acs.jmedchem.5b00386. PMC 5159624. PMID 25992880.
[続きの解説]
「ステリルスルファターゼ」の続きの解説一覧
- 1 ステリルスルファターゼとは
- 2 ステリルスルファターゼの概要
- 3 関連項目
- ステリルスルファターゼのページへのリンク
