ガルノン
ガルノン
出典: フリー百科事典『ウィキペディア（Wikipedia）』 (2022/07/26 09:40 UTC 版)
ガルノン(Galnon)は、ガラニン受容体GALRの選択的アゴニストである[1][2]。動物実験では、抗てんかん薬、抗不安薬、食欲減退薬、健忘の効果が見られた[3][4][5][6][7]。
- ^ Saar K, Mazarati AM, Mahlapuu R, Hallnemo G, Soomets U, Kilk K, Hellberg S, Pooga M, Tolf BR, Shi TS, Hökfelt T, Wasterlain C, Bartfai T, Langel U (May 2002). “Anticonvulsant activity of a nonpeptide galanin receptor agonist”. Proceedings of the National Academy of Sciences of the United States of America 99 (10): 7136–41. doi:10.1073/pnas.102163499. PMC 124541. PMID 12011470.
- ^ Sollenberg U, Bartfai T, Langel U (June 2005). “Galnon--a low-molecular weight ligand of the galanin receptors”. Neuropeptides 39 (3): 161–3. doi:10.1016/j.npep.2004.12.019. PMID 15944006.
- ^ Abramov U, Florén A, Echevarria DJ, Brewer A, Manuzon H, Robinson JK, Bartfai T, Vasar E, Langel U (February 2004). “Regulation of feeding by galnon”. Neuropeptides 38 (1): 55–61. doi:10.1016/j.npep.2004.01.001. PMID 15003717.
- ^ Badie-Mahdavi H, Behrens MM, Rebek J, Bartfai T (June 2005). “Effect of galnon on induction of long-term potentiation in dentate gyrus of C57BL/6 mice”. Neuropeptides 39 (3): 249–51. doi:10.1016/j.npep.2004.12.010. PMID 15944018.
- ^ Rajarao SJ, Platt B, Sukoff SJ, Lin Q, Bender CN, Nieuwenhuijsen BW, Ring RH, Schechter LE, Rosenzweig-Lipson S, Beyer CE (October 2007). “Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon”. Neuropeptides 41 (5): 307–20. doi:10.1016/j.npep.2007.05.001. PMID 17637475.
- ^ Kozlovsky N, Matar MA, Kaplan Z, Zohar J, Cohen H (March 2009). “The role of the galaninergic system in modulating stress-related responses in an animal model of posttraumatic stress disorder”. Biological Psychiatry 65 (5): 383–91. doi:10.1016/j.biopsych.2008.10.034. PMID 19095221.
- ^ Narasimhaiah R, Kamens HM, Picciotto MR (May 2009). “Effects of galanin on cocaine-mediated conditioned place preference and ERK signaling in mice”. Psychopharmacology 204 (1): 95–102. doi:10.1007/s00213-008-1438-7. PMC 2872184. PMID 19099295.
[続きの解説]
「ガルノン」の続きの解説一覧
- 1 ガルノンとは
- 2 ガルノンの概要
- ガルノンのページへのリンク
