獲得免疫系とは? わかりやすく解説

Weblio 辞書 > 辞書・百科事典 > 百科事典 > 獲得免疫系の意味・解説 

獲得免疫系

出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2022/07/31 15:33 UTC 版)

獲得免疫系(かくとくめんえきけい、acquired immune system)または適応免疫系(てきおうめんえきけい、adaptive immune system)とは、免疫系のサブシステムであり、病原体を排除またはその増殖を防止する特殊で全身的な細胞やプロセスで構成されている。獲得免疫系は、脊椎動物に見られる2つの主要な免疫戦略のうちの1つである(もう1つは自然免疫系)。


注釈

  1. ^ ヘモグロビンS。異常ヘモグロビンの一種で、鎌状赤血球貧血や溶血性貧血等の原因となる。

出典

  1. ^ a b c d e f Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walters P (2002). Molecular Biology of the Cell (4th ed.). New York and London: Garland Science. ISBN 0-8153-3218-1. https://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowTOC&rid=mboc4.TOC&depth=2 
  2. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z Janeway CA, Travers P, Walport M, Shlomchik MJ (2001). Immunobiology (5th ed.). New York and London: Garland Science. ISBN 0-8153-4101-6. https://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowTOC&rid=imm.TOC&depth=10 
  3. ^ The innate and adaptive immune systems. Institute for Quality and Efficiency in Health Care (IQWiG). (4 August 2016). https://www.ncbi.nlm.nih.gov/books/NBK279396/#_i2255_theadaptiveimmunesys_ 
  4. ^ Microbiology and Immunology On-Line Textbook”. University of South Carolina School of Medicine. 2008年9月2日時点のオリジナルよりアーカイブ。2021年11月17日閲覧。
  5. ^ a b c d e f g h i j k Janeway CA, Travers P, Walport M, Shlomchik MJ (2005). Immunobiology. (6th ed.). Garland Science. ISBN 0-443-07310-4 
  6. ^ a b c Understanding the Immune System How It Works”. NIH Publication No. 03-5423. National Institute of Allergy and Infectious Diseases National Cancer Institute, U.S. Department of Health and Human Services National Institutes of Health (2003年9月). 2007年1月3日時点のオリジナルよりアーカイブ。2021年11月18日閲覧。
  7. ^ Spencer LA, Weller PF (2010). “Eosinophils and Th2 immunity: contemporary insights”. Immunology and Cell Biology 88 (3): 250-256. doi:10.1038/icb.2009.115. PMC 3589820. PMID 20065995. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589820/. 
  8. ^ Szabo PA, Levitin HM, Miron M, Snyder ME, Senda T, Yuan J, Cheng YL, Bush EC, Dogra P, Thapa P, Farber DL, Sims PA (October 2019). “Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease”. Nature Communications 10 (1): 4706. Bibcode2019NatCo..10.4706S. doi:10.1038/s41467-019-12464-3. PMC 6797728. PMID 31624246. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797728/. 
  9. ^ Magen A, Nie J, Ciucci T, Tamoutounour S, Zhao Y, Mehta M, Tran B, McGavern DB, Hannenhalli S, Bosselut R (December 2019). “+ T Cells” (英語). Cell Reports 29 (10): 3019-3032.e6. doi:10.1016/j.celrep.2019.10.131. PMC 6934378. PMID 31801070. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934378/. 
  10. ^ Weinstein JS, Hernandez SG, Craft J (May 2012). “T cells that promote B-Cell maturation in systemic autoimmunity”. Immunological Reviews 247 (1): 160-171. doi:10.1111/j.1600-065x.2012.01122.x. PMC 3334351. PMID 22500839. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334351/. 
  11. ^ Flajnik, Martin F. (19 March 2018). “A cold-blooded view of adaptive immunity”. Nature Reviews Immunology 18 (7): 438-453. doi:10.1038/s41577-018-0003-9. PMC 6084782. PMID 29556016. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084782/. 
  12. ^ Kasamatsu, Jun (January 2013). “Evolution of innate and adaptive immune systems in jawless vertebrates” (英語). Microbiology and Immunology 57 (1): 1-12. doi:10.1111/j.1348-0421.2012.00500.x. ISSN 0385-5600. PMID 22924515. 
  13. ^ Alder MN, Rogozin IB, Iyer LM, Glazko GV, Cooper MD, Pancer Z (December 2005). “Diversity and function of adaptive immune receptors in a jawless vertebrate”. Science 310 (5756): 1970-1973. Bibcode2005Sci...310.1970A. doi:10.1126/science.1119420. PMID 16373579. 
  14. ^ Mikonranta L, Mappes J, Kaukoniitty M, Freitak D (March 2014). “Insect immunity: oral exposure to a bacterial pathogen elicits free radical response and protects from a recurring infection”. Frontiers in Zoology 11 (1): 23. doi:10.1186/1742-9994-11-23. PMC 3975449. PMID 24602309. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975449/. 
  15. ^ Sadd BM, Schmid-Hempel P (June 2006). “Insect immunity shows specificity in protection upon secondary pathogen exposure” (英語). Current Biology 16 (12): 1206-1210. doi:10.1016/j.cub.2006.04.047. PMID 16782011. 
  16. ^ Pham LN, Dionne MS, Shirasu-Hiza M, Schneider DS (March 2007). “A specific primed immune response in Drosophila is dependent on phagocytes”. PLOS Pathogens 3 (3): e26. doi:10.1371/journal.ppat.0030026. PMC 1817657. PMID 17352533. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1817657/. 
  17. ^ Hernández López J, Schuehly W, Crailsheim K, Riessberger-Gallé U (June 2014). “Trans-generational immune priming in honeybees”. Proceedings. Biological Sciences 281 (1785): 20140454. doi:10.1098/rspb.2014.0454. PMC 4024302. PMID 24789904. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024302/. }
  18. ^ Roth O, Joop G, Eggert H, Hilbert J, Daniel J, Schmid-Hempel P, Kurtz J (March 2010). “Paternally derived immune priming for offspring in the red flour beetle, Tribolium castaneum”. The Journal of Animal Ecology 79 (2): 403-413. doi:10.1111/j.1365-2656.2009.01617.x. PMID 19840170. 
  19. ^ a b Dong Y, Taylor HE, Dimopoulos G (July 2006). “AgDscam, a hypervariable immunoglobulin domain-containing receptor of the Anopheles gambiae innate immune system”. PLOS Biology 4 (7): e229. doi:10.1371/journal.pbio.0040229. PMC 1479700. PMID 16774454. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479700/. 
  20. ^ Meki IK, Kariithi HM, Parker AG, Vreysen MJ, Ros VI, Vlak JM, van Oers MM, Abd-Alla AM (November 2018). “RNA interference-based antiviral immune response against the salivary gland hypertrophy virus in Glossina pallidipes”. BMC Microbiology 18 (Suppl 1): 170. doi:10.1186/s12866-018-1298-1. PMC 6251114. PMID 30470195. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251114/. 
  21. ^ Rubio M, Maestro JL, Piulachs MD, Belles X (June 2018). “Conserved association of Argonaute 1 and 2 proteins with miRNA and siRNA pathways throughout insect evolution, from cockroaches to flies”. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1861 (6): 554?60. doi:10.1016/j.bbagrm.2018.04.001. hdl:10261/168051. PMID 29656113. 
  22. ^ International Human Genome Sequencing Consortium (October 2004). “Finishing the euchromatic sequence of the human genome”. Nature 431 (7011): 931-945. Bibcode2004Natur.431..931H. doi:10.1038/nature03001. PMID 15496913. 
  23. ^ Mi S, Lee X, Li X, Veldman GM, Finnerty H, Racie L, LaVallie E, Tang XY, Edouard P, Howes S, Keith JC, McCoy JM (February 2000). “Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis”. Nature 403 (6771): 785-789. Bibcode2000Natur.403..785M. doi:10.1038/35001608. PMID 10693809. 
  24. ^ Villarreal, Luis P.. “The Viruses That Make Us: A Role For Endogenous Retrovirus In The Evolution Of Placental Species”. University of California, Irvine (lecture notes). 2007年7月15日時点のオリジナルよりアーカイブ。2008年2月3日閲覧。
  25. ^ Villarreal, Luis P. (Oct 2001). “Persisting Viruses Could Play Role in Driving Host Evolution”. ASM News. オリジナルの2009-05-08時点におけるアーカイブ。. https://web.archive.org/web/20090508113235/http://newsarchive.asm.org/oct01/feature1.asp. 
  26. ^ a b c Uematsu S, Akira S (May 2007). “Toll-like receptors and Type I interferons”. The Journal of Biological Chemistry 282 (21): 15319-15323. doi:10.1074/jbc.R700009200. PMID 17395581. 
  27. ^ Kuross SA, Rank BH, Hebbel RP (April 1988). “Excess heme in sickle erythrocyte inside-out membranes: possible role in thiol oxidation”. Blood 71 (4): 876-882. doi:10.1182/blood.V71.4.876.876. PMID 3355895. https://doi.org/10.1182/blood.V71.4.876.876. 
  28. ^ Arese P, Turrini F, Schwarzer E (2005). “Band 3/complement-mediated recognition and removal of normally senescent and pathological human erythrocytes”. Cellular Physiology and Biochemistry 16 (4?6): 133-146. doi:10.1159/000089839. PMID 16301814. 
  29. ^ Williams TN, Mwangi TW, Roberts DJ, Alexander ND, Weatherall DJ, Wambua S, Kortok M, Snow RW, Marsh K (May 2005). “An immune basis for malaria protection by the sickle cell trait”. PLOS Medicine 2 (5): e128. doi:10.1371/journal.pmed.0020128. PMC 1140945. PMID 15916466. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140945/. 
  30. ^ Schofield L, Grau GE (September 2005). “Immunological processes in malaria pathogenesis”. Nature Reviews. Immunology 5 (9): 722-735. doi:10.1038/nri1686. PMID 16138104. 
  31. ^ a b Flajnik MF, Kasahara M (January 2010). “Origin and evolution of the adaptive immune system: genetic events and selective pressures”. Nature Reviews. Genetics 11 (1): 47-59. doi:10.1038/nrg2703. PMC 3805090. PMID 19997068. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805090/. 
  32. ^ Hibino T, Loza-Coll M, Messier C, Majeske AJ, Cohen AH, Terwilliger DP, Buckley KM, Brockton V, Nair SV, Berney K, Fugmann SD, Anderson MK, Pancer Z, Cameron RA, Smith LC, Rast JP (December 2006). “The immune gene repertoire encoded in the purple sea urchin genome”. Developmental Biology 300 (1): 349?65. doi:10.1016/j.ydbio.2006.08.065. PMID 17027739. https://authors.library.caltech.edu/35195/2/mmc1.pdf. 
  33. ^ Pancer Z, Amemiya CT, Ehrhardt GR, Ceitlin J, Gartland GL, Cooper MD (July 2004). “Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey”. Nature 430 (6996): 174-180. Bibcode2004Natur.430..174P. doi:10.1038/nature02740. hdl:2027.42/62870. PMID 15241406. https://hdl.handle.net/2027.42/62870. 
  34. ^ Rogozin IB, Iyer LM, Liang L, Glazko GV, Liston VG, Pavlov YI, Aravind L, Pancer Z (June 2007). “Evolution and diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase”. Nature Immunology 8 (6): 647-656. doi:10.1038/ni1463. PMID 17468760. 
  35. ^ Boehm T (May 2011). “Design principles of adaptive immune systems”. Nature Reviews. Immunology 11 (5): 307-317. doi:10.1038/nri2944. PMID 21475308. 





英和和英テキスト翻訳>> Weblio翻訳
英語⇒日本語日本語⇒英語
  
  •  獲得免疫系のページへのリンク

辞書ショートカット

すべての辞書の索引

「獲得免疫系」の関連用語

獲得免疫系のお隣キーワード
検索ランキング

   

英語⇒日本語
日本語⇒英語
   



獲得免疫系のページの著作権
Weblio 辞書 情報提供元は 参加元一覧 にて確認できます。

   
ウィキペディアウィキペディア
All text is available under the terms of the GNU Free Documentation License.
この記事は、ウィキペディアの獲得免疫系 (改訂履歴)の記事を複製、再配布したものにあたり、GNU Free Documentation Licenseというライセンスの下で提供されています。 Weblio辞書に掲載されているウィキペディアの記事も、全てGNU Free Documentation Licenseの元に提供されております。

©2024 GRAS Group, Inc.RSS