山口正義 (生理学者)とは? わかりやすく解説

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山口正義 (生理学者)

出典: フリー百科事典『ウィキペディア(Wikipedia)』 (2023/08/09 19:13 UTC 版)

山口 正義(やまぐち まさよし)は、日本、アメリカ合衆国薬学者生物系薬学医療系薬学)。学位は薬学博士静岡薬科大学)。静岡県立大学大学院生活健康科学研究科教授、米国 エモリー大学 医学部客員教授 および Adjunct Professor, カリフォルニア大学 ロスアンジェルス校 (UCLA) 医学部 客員教授、ハワイ大学がんセンター 教授などを歴任。USERN (The Universal Scientific Education and Research Network)のAdvisory Board メンバーを務める。さらに、米国において1886年に創立された Sigma Xi (The Scientific Research Honor Society)の Full Member に登録された。


  1. ^ http://researchmap.jp/my-1102443
  2. ^ Masayoshi Yamaguch, M. Neale Weitzmann: The estrogen 17β-estradiol and phytoestrogen genistein mediate differential effects on osteoblastic NF-κB activity.International Journal of Molecular Medicine, 23:297-301 (2009)
  3. ^ Ofotokun, Kehmia Titanji, Tatyana Vikulina, Susanne Roser-Page, Masayoshi Yamaguchi, Majd Zayzafoon, Ifor R. Williams, M. Neale Weitzmann:Role of T cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss.Nature Communications 6:8282 (2015) DOI: 10.1038/ncomms9282
  4. ^ Masayoshi Yamaguchi, Tomiyasu Murata: Involvement of regucalcin in lipid metabolism and diabetes. Metabolism Clinical and Experimental, 62:1045-1051 (2013)
  5. ^ Masayoshi Yamaguchi, Tomiyasu Murata, Mamoru Shoji, M. Neale Weitzmann:The flavonoid p-hydroxycinnamic acid mediates anticancer effects on MDA-MB-231 human breast cancer cells in vitro: Implications for suppression of bone metastases.International Journal of Oncology, 47: 1563-1571 (2015)
  6. ^ Masayoshi Yamaguchi, Satoru Osuka, M. Neale Weitzmann, Bassel F. El-Rayes, Mamoru Shoji , Tomiyasu Murata: Prolonged survival in pancreatic cancer patients with increased regucalcin gene expression: Overexpression of regucalcin suppresses the proliferation in human pancreatic cancer MIA PaCa-2 cells in vitro. International Journal of Oncology, 48:1955-1964 (2016)
  7. ^ https://www.researchgate.net/scientific-contributions/38112273_Masayoshi_Yamaguchi
  8. ^ Yamaguchi M, Hankinson O (2018) 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin suppresses the growth of human liver cancer HepG2 cells in vitro: Involvement of cell signaling factors. Int J Oncol 53:1657-1666
  9. ^ Masayoshi Yamaguchi, Satoru Osuka, Oliver Hankinson, Tomiyasu Murata: Prolonged survival of renal cancer patients is concomitant with a higher regucalcin gene expression in the tumor tissues: Overexpression of regucalcin depresses the growth of human renal cell carcinoma cells in vitro. International Journal of Oncology, 54: 188-198(2019)
  10. ^ https://www.hawaii.edu/directory/
  11. ^ a b https://orcid.org/0000-0002-8511-110X
  12. ^ a b https://www.uhcancercenter.org/yamaguchi-masayoshi
  13. ^ "Research", Masayoshi Yamaguchi Archived 2011年8月7日, at the Wayback Machine. Emory University.
  14. ^ Masayoshi Yamaguchi, Takeo Yamamoto: Purification of calcium binding substance from soluble fraction of normal rat liver. Chemical & Pharmaceutical Bulletin,26:1915-1918 (1978)
  15. ^ Masayoshi Yamaguchi, Seiichi Mori: Effects of Ca2+ and Zn2+ on 5’-nucleotidase activity in rat liver plasma membranes: Hepatic calcium-binding protein (regucalcin) reverses the Ca2+ effect. Chemical & Pharmaceutical Bulletin, 36:321-325 (1988).
  16. ^ Masayoshi Yamaguchi: Novel protein RGPR-p117: its role as the regucalcin gene transcription factor. Molecular and Cellular Biochemistry, 327: 53-63 (2009)
  17. ^ Yamaguchi: Book title: Regucalcin: Genomics, Cell Regulation and Disease. Nova Science Publishers, Inc., New York, USA, 2012
  18. ^ Masayoshi Yamaguchi: Book title: The Role of Regucalcin in Cell Homeostasis and Disorder.Nova Science Publishers, Inc., New York, USA, Chapter 1-18, pp.1-275, 2017.
  19. ^ Masayoshi Yamaguchi: Suppressive role of regucalcin in liver cell proliferation: Involvement in carcinogenesis. Cell Proliferation, 46:243-253 (2013)
  20. ^ Masayoshi Yamaguchi: Involvement of regucalcin as a suppressor protein in human carcinogenesis: Insight into the the gene therapy. Journal of Cancer Research and Clinical Oncology, 141:1333-1341 (2015)
  21. ^ Yamaguchi, M.; Osuka, S.; Hankinson, O.; Murata, T. Prolonged survival of renal cancer patients is concomitant with a higher regucalcin gene expression in the tumor tissues: Overexpression of regucalcin depresses the growth of human renal cell carcinoma cells in vitro. Int. J. Oncol. 2019, 54, 188-198.
  22. ^ Nitschkowski D, Marwitz S, Kotanidou SA, Reck M, Kugler C, Rabe KF, Ammerpohi O, Goldmann T (2019) Live and let die: epigenetic modifications of Survivin and Regucalcin in non-small cell lung cancer tissues contribute to malignancy. Clin Epigenetics 11:157, doi.org/10.1186/s13148-019-0770-6.
  23. ^ Masayoshi Yamaguchi, Tomiyasu Murata:Involvement of regucalcin gene promoter region-related protein-117, a transcription factor, in human obesity (Review).Biomedical Reports 6:374-378 (2017).
  24. ^ 山口正義:骨の健康と食因子-骨粗鬆症の予防と修復へのアプローチ、食品素材研究会、東京、2010年
  25. ^ Masayoshi Yamaguchi: Book title: Biomedical Osteoporosis Treatment. Nova Science Publishers, Inc., New York, USA, 2013.
  26. ^ Composition for stimulating osteogenesis and preventing reduction of bone salt. United States Patent. Patent Number: 5,935,996 Registered: August 10, 1999, Inventor: Masayoshi Yamaguchi (Japan), Assignee: Masayoshi Yamaguchi (Japan)
  27. ^ Method for suppressing proliferation and/or inducing apoptosis of cancer cells. USA Patent Number: US 9937216 B2, Registered: April 10, 2018 , Inventor: Masayoshi Yamaguchi (Japan)Assignee: Maruhachi Muramatu, Inc. (Japan)
  28. ^ Model Animal with Overexpression of Regucalcin, United States Patent Patent No.: US7,355,093 B2, Registered: April 8, 2008, Inventor: Masayoshi Yamaguchi, Assignee: Japan Science and Technology Agency (Japan)
  29. ^ Rat model with overexpression of regucalcin. European Patent. Patent Number 1437043 (England, France, Deutch, Switherland, Italy, Netherland). Registered: January 5, 2011, Inventor: Masayoshi Yamaguchi (Japan), Assignee: Japan Science and Technology Agency (Japan)
  30. ^ https://researchmap.jp/read0179985
  31. ^ Endocrinology & Metabolic Syndrome (2011- 2020)
  32. ^ International Journal of Diabetes and Clinical Research (2014-)
  33. ^ https://benthamscience.com/journal/217/editorial-board
  34. ^ https://www.amazon.com/Masayoshi-Yamaguchi/e/B0039X63C4%3Fref=dbs_a_mng_rwt_scns_share
  35. ^ https://wwlifetimeachievement.com/2017/07/20/masayoshi-yamaguchi/
  36. ^ https://www.24-7pressrelease.com/press-release/441521/dr-masayoshi-yamaguchi-named-a-lifetime-achiever-by-marquis-whos-who
  37. ^ http://www.interpaper.org/MEMBERS.htm
  38. ^ https://usern.tums.ac.ir/
  39. ^ https://vdgood.org
  40. ^ https://www.sigmaxi.org/members/member-directoryfn=Masayoshi&ln=Yamaguchi&disc=0&chap=Membership%20At%20Large&match=False
  41. ^ 学位論文書誌データベース
  42. ^ https://manoa.hawaii.edu/directory/index.php
  43. ^ https://www.kinokuniya.co.jp/f/dsg-01-9784879910028


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