Insulin
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
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Subheadings:
Tree Number(s): D06.472.699.587.200.500.625, D12.644.548.586.200.500.625
MeSH Unique ID: D007328
Entry Terms:
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
- Insulin A Chain
- Sodium Insulin
- Insulin, Sodium
- Novolin
- Iletin
- Insulin B Chain
- Chain, Insulin B
See Also:
Pharmacologic Action: